Chemical handling procedures

Workers should be trained in the hazards that they are potentially exposed to. The handling proeedures that are adopted should ensure that whatever the hazards present, they are adequately eontrolled. Some typieal eontrol proeedures inelude  

Beeause this list is general in nature, the user will have to modify it to be sure that site speeifieity and applieability are taken into aeeount. 

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Chemicals used in the quality control analyses in the shieided glove box (SGB) and ventilation hoods of the Quality Control Laboratory involve small (less than a liter) quantities of some acidic and basic chemicals, including ammonium thiocyanate, stannous chloride, sulfuric, nitric, and hydrochloric acids, ferric sulfate, carrier solutions, ethyl acetate, sodium nitrite, chloroform, sodium hydroxide, and potassium iodide. Material Safety Data Sheets for any processes implemented in the HCF are reviewed in accordance with the SNL ES H Manual to identify any carcinogens or other hazardous materials. Operations in the SGB for preparation of various Mo-99 product dilution samples would require a small bulk supply of sodium hydroxide (0.1 N NaOH). Quality control analysis sample preparation operations require small bulk supplies of the above chemicals. Workers performing quaiify control analysis use chemical handling procedures as required by the Sandia ES H Manual. 

Any spills are contained in a spill tray and cleaned up with a spill kit -Workers performing quality control analysis use basic safe chemical handling procedures as spelled out in the Sandia ES H Manual. 

Casale, Robin J. 2001. Improving Chemical Handling Procedures Can Help Reduce Associated Treatment Problems. Journal AWWA 93, Part 9... 

Scrutiny of all chemical handling procedures including shipping, receiving, storage, use, and waste tracking. 

Strong legal provisions and standard procedures in chemical industry and chemical handling must be in force. 

For the decomposition of organic materials, wet chemical methods are most frequently used. The wide acceptance of these methods is due to the multitude of decomposition reagents available, simple handling procedures and high sample throughput. The error sources listed above can largely be eliminated if wet chemical methods are properly handled. 

Sound practice dictates that storage tanks and process vessels containing hazardous chemicals be properly designed and used only for their intended purpose. They should also have, as a minimum, overflow alarms. Once these conditions are met, it remains to ensure the structural soundness of the containers, to enforce proper hazardous materials handling procedures, and to construct and maintain secondary containment and collection facilities (Shields 1980). 

Rules of laboratory safety and chemical handling are not designed to impede productivity, nor should they instill a fear of chemicals or laboratory procedures. Rather, their purpose is to create a healthy awareness of potential laboratory hazards, to improve the efficiency of each student... 

The experiments in this book have been exhaustively tested for safety and all attempts have been made to use the least hazardous chemicals and procedures possible. However, the author and publisher cannot be held liable for any injury or damage which may occur during the performance of the experiments. It is assumed that before an experiment is initiated, a Material Safety Data Sheet (MSDS) for each chemical used will have been studied by the instructor and students to ensure its safe handling and disposal. 

We have previously described the basic resin handling and washing procedures, as well as nitro group reduction, cyclization with aldehydes to form the benzimidazole ring, and chemical encoding procedures for a related benzimidazole system.18 Reagents and solvents used are available from Aldrich (Milwaukee, WI) and Calbiochem-Novabiochem (San Diego, CA). 

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