Chemical carcinogens suspected

Pipetting. All liquid transfer operations are performed with mechanical pipetting aids. Figure 3 also see the Source table (6). Oral pipetting is not performed in a laboratory engaged in research work with chemical carcinogens, suspect carcinogens, or other toxic substances (7). 

Armour, M.A., Disposal methods for some known or suspect chemical carcinogens, in Recent Advances of Chemistry and Molecular Biology in Cancer Research, Dai, Q., Armour, M.A., and Zheng, Q., Eds., Springer-Verlag, Heidelberg, 1993, p. 315 Armour, M.A., Chemical treatment methods to minimize waste, in Pollution Prevention and Waste Minimization in Laboratories, Reinhardt, P.A. et al., Eds., Lewis Publishers, Boca Raton, FL, 1995, p. 283. 

Collection of chemical carcinogens, all waste products, animal carcasses and other materials from the laboratory should be performed by designated personnel on a scheduled basis or when necessary. The suspect or carcinogenic materials should not be placed on uncontrolled loading docks for pickup by general refuse collection personnel. At the National Institutes of Health, the special collection of hazardous materials, including chemical carcinogens, is done by personnel of the Fire Department. In the instance of one of the NCI contractor sites, Frederick Cancer Research Center, located at a military post, personnel from the safety offices perform this service. 

Specific temperatures for the incineration of all known or suspected chemical carcinogens have not been determined. Work conducted at the National Center for Toxicological Research Laboratories (NCTRL), Food and Drug Administration, Jefferson, Arkansas 72079 has shown that 2-Acetylaminofluorene may be... 

Design features of facilities used for research on regulated chemical carcinogens or suspect chemicals are generally similar to those used for work with infectious microorganisms or the requirements recently promulgated for recombinant DNA research (8). 

Entrances to facilities used for research with chemical carcinogens must be controlled at points of access. Access points where chemical carcinogens or suspect chemicals are used must be posted with appropriate signs DANGER—CHEMICAL CARCINOGEN-AUTHORIZED PERSONNEL ONLY. A shower should be available within the facility to personnel working with known or suspect chemical... 

The facility must be designed to control access. Signs should designate restricted areas. Clothing requirements for entry should be identified. There should be directional air control with adequate ventilation rates. Primary containment equipment such as chemical fume hoods, a Class I or Class II (Type B) biological safety cabinet, or a glove box system should be available for use with known or suspect chemical carcinogens or other toxic substances. 

U.S. Department of Health, Education, and Welfare, National Institutes of Health. Disposal of suspected or known chemical carcinogenic material at NIH. Manual Issuance 3032-2. NIH - 1511-1. 

The following pages provide, in brief, lists of known carcinogens, suspected carcinogens, and probable carcinogens. Proper use and careful management of chemical substances protect human health and safety and the living environment. 

DFG MAK Confirmed Animal Carcinogen, Suspected Human Carcinogen SAFETY PROFILE Confirmed carcinogen. Poison by ingestion. Moderately toxic by inhalation and skin contact. Experimental reproductive effects. A skin and severe eye irritant. Mutation data reported. Moderately flammable by heat, flames (sparks), or powerful oxidizers. See also v LLYL COMPOUNDS and CHLORINATED HYDROCARBONS, ALIPHATIC. When heated to decomposition it yields highly toxic Cr. To fight fire, use water (as a blanket), spray, mist, dry chemical. 

Several agencies have compiled lists of chemicals that are either established or suspected human carcinogens. The most widely used list is that of the IARCJ9 Other lists of chemical carcinogens include... 

Scorecard. The pollution information site. Health effects—carcinogens. Suspected carcinogens, www.scorecard.org/health-effects/chemicals.tcl7short hazard name=cancer all p=t... 

A draft cancer risk policy for California (17) expresses as a goal that the risk from exposure to a chemical carcinogen in drinking water should not exceed one person affected per million population exposed. Analytical techniques for known or suspected carcinogens must be refined to enable detection at levels that are relevant to this risk assessment policy. 

Toxicology LD50 (IP, rat) 403 mg/kg, (subcut., mouse) 830 mg/kg mod. toxic by ing., IP, subcut. routes CNS depressant inh. can probably cause si. nose/throat irritation, mild CNS depression high doses can cause unconsciousness, death probable skin and si. eye irritant may be si. absorbed thru skin liq. may cause temporary corneal damage related chemicals are suspected human carcinogens mutagen TSCA iisted... 

Pipetting must always be performed using mechanical systems. Oral pipetting of known or suspected chemical carcinogens, their solutions, or of toxic compounds, should not, under any circumstances be allowed. 

Grdinic, V. Jaksevac-Miksa, M. Stefanini-Oresic, L. Ion-exchange resin as reaction medium for microdetection of some chemical carcinogens and cancer suspect agents. Acta Pharm. Jugoslavica 1984, 34, 87-92. 

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