Powdered cellulose

Hydroxynaphthol Blue tri-Na salt [63451-35-4] M 620.5, m dec on heating, pKE,t <0. Crude material was treated with hot EtOH to remove soluble impurities, then dissolved in 20% aqueous MeOH and chromatographed on a cellulose powder column with propanol EtOH water (5 5 4) as eluent. The upper of three zones was eluted to give the pure dye which was ppted as the monosodium salt trihydrate by adding cone HCl to the concentrated eluate [Ito and Ueno zfna/ysr 95 583 1970. ... 

Porphyrin a (from ox heart) [5162-02-1] M 799.0, m dec on heating. Purified on a cellulose powder column followed by extraction with 17% HCl and fractionation with HCl. [Morell et al. Biochem J 78... 

This Crude product (15.8 g) In water (360 ml) was added to a prehydrogenated suspension of 10% palladium on charcoal (4 g) in water (400 ml), and hydrogenation was continued for 30 minutes. The catalyst was removed and the filtrate was adjusted to pH 7.5 with sodium bicarbonate, then evaporated at low temperature and pressure. The residue was purified by chromatography on a column of cellulose powder, eluting first with butanol/ ethanol/water mixture and then with acetone/isopropanol/water. The main fraction was evaporated at low temperature and pressure to give a 32% yield of the sodium salt of a-carboxybenzylpenicillin as a white powder. The product was estimated by manometric assay with penicillinase to be 58% pure. 

Technique of thin-layer chromatography. Preparation of the plate. In thin-layer chromatography a variety of coating materials is available, but silica gel is most frequently used. A slurry of the adsorbent (silica gel, cellulose powder, etc.) is spread uniformly over the plate by means of one of the commercial forms of spreader, the recommended thickness of adsorbent layer being 150-250 m. After air-drying overnight, or oven-drying at 80-90 °C for about 30 minutes, it is ready for use. 

The extracted crude luciferin was purified by Anderson s benzoy-lation method mentioned above (Anderson, 1935), followed by partition chromatography on a cellulose powder column using a mixture of ethyl acetate-ethanol-water (5 2 3 Tsuji, 1955) as the solvent, again in a hydrogen atmosphere. The luciferin obtained (3 mg) was highly pure by paper chromatography, and appeared suitable for crystallization. I... 

A novel TLC spectrofluorometric method for identification and determination of selenium in different food samples of animal and vegetable origin has been proposed [30]. The procedure involves the digestion of food sample (1 to 5 g) in the presence of cone. HNO3 (5 ml), 70% HCIO4 (10 ml), and FIjO (10 ml) in a 250-ml Kjeldahl flask reduction of Se(VI) into Se(IV) complexation of the isolated selenium with 23-diaminonaphthene (DAN) extraction of the resultant Se—DAN complex with cyclohexane and spectrofluorometric determination followed by confirmation of the presence of Se in the sample by TLC using thin layers of MN-300 cellulose powder. 

Measurements of particle porosity are a valuable supplement to studies of specific surface area, and such data are particularly useful in the evaluation of materials used in direct compression processes. For example, both micromeritic properties were measured for several different types of cellulosic-type excipients [53]. Surface areas by the B.E.T. method were used to evaluate all types of pore structures, while the method of mercury intrusion porosimetry used could not detect pores smaller than 10 nm. The data permitted a ready differentiation between the intraparticle pore structure of microcrystalline and agglomerated cellulose powders. 

In a partition system the stationary phase is a liquid coated onto a solid support (p. 97). Silica gel, kieselguhr (diatomaceous earth) or cellulose powder are the most frequently used. Conditions closely resemble those of counter-current distribution so that in the absence of adsorption by the solid support, solutes move through the system at rates determined by their... 

Liquid ion-exchangers have been discussed in the section on solvent extraction (p. 65). They can be used in column form by coating them on to a solid support such as cellulose powder or Kel-F (polytrifluorochloroethylene). Tris-n-octylamine (TNOA) and bis(2-ethylhexyl)phosphoric acid (HDEHP) behave as strong-base and strong-acid exchangers for anions and cations respectively. 

Wayman et al studied the binding of neomycin to the filtration materials celite, cellulose powder and Seitz filters. Neomycin was found to be adsorbed on all three materials. Acid-washing the cellulose powder failed to desorb all of the neomycin. 

Pesonen, T., Paronen, P., and Ketolainen, Disintegrant properties of an agglomerated cellulose powder, Im. J. Pharm., 57 139-147 (1989). 

Filtrasorb 300 Filtrasorb 300 Activated charcoal Anion-exchange resin Cation-exchange resin Cellulose powder Cellulose triacetate Kaolinite... 

For conventional or normal, in contrast with reversed-phase, LLPC, many materials have been used as the solid support for the stationary liquid. In addition to silica gel, which was the first and is still the most popular material, a variety of other adsorbents that adsorb the polar solvent such as cellulose powder, starch, alumina, and silicic acid have been used. The more recent practice of HPLC has greatly simplified the technique in providing column stability for repeated use and for treatment of large volumes. 

A. Gupta, G.E. Peck, R.W. Miller and K.R. Morris, Influence of ambient moisture on the compaction behavior of microcrystalline cellulose powder undergoing uni-axial compression and roller compaction a comparative study using near-infrared spectroscopy, J. Pharm. Sci., 94(10), 2301-2313 (2005). 

Cellulose powder is now stirred into the cooled solution until the mass can still just be stirred.The contents of the flask are then transferred to a large beaker and more cellulose powder is kneaded in by hand (wear rubber gloves ) until a total of 35 g has been added.The crumbled mixture is dried for 24 h at 50 °C in the vacuum oven. Finally, the dried product is finely ground in a mortar, mixed with 1% of ammonium chloride and 1 % of zinc stearate (as lubricant) and crosslinked (cured) by heating to about 160 C for 10 min in a simple press at 300-400 bar. A thin transparent plate is obtained that is no longer soluble in or attacked by water this is more convincing if a small piece is allowed to stand overnight in a beaker of water. 

Whatman CFll fibrous cellulose powder is prepared for chromatography... 

To obtain individual sialic acids in pure, or almost pure, form, the sialic acid mixture obtained from the procedures just described are subjected to partition chromatography on cellulose powder, using, as the solvent,74107 1 2 1 (v/v/v) 1 -butanol-l-propanol-water. The (less hydrophilic) tri- and di-O-acetylated sialic acids are eluted first, followed by mono-O-acetylated sialic acids, NeuoAc, and Neu5Gc, ac-... 

Celestone syrup contains 0.6 mg betamethasone in each 5 mL. The inactive ingredients for celestone syrup include alcohol cellulose, powdered citric acid, anhydrous FD C red no. 40 FD C yellow no. 6 flavor cherry... 

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