Cancer Carcinogenicity

Carcinogens Cancer-producing agents Skin Respiratory Bladder/urinary tract Liver Nasal Bone marrow Coal tar pitch dust crude anthracene dust mineral oil mist arsenic. Asbestos polycyclic aromatic hydrocarbons nickel ore arsenic bis-(chloromethyl) ether mustard gas. p-naphthylamine benzidine 4-am i nodi pheny lam ine. Vinyl chloride monomer. Mustard gas nickel ore. Benzene. 

If OSHA, the National Toxicology Program (NTP), or tire International Agency for Research on Cancer (lARC) listed the compound as a carcinogen (cancer causing agent), it must be indicated as such on Uie MSDS. 

Le Marchand, L., Sivaraman, L. et al. (1998). Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens. Cancer Res., 58(21), 4858-63. 

Wattenberg LW. 1975. Effects of dietary constituents on the metabolism of chemical carcinogens. Cancer Res 35(11) 3326—3331. 

Parodi, S., S.DeFlora, M.Cavanna, and others. 1981. DNA-damaging activity in vivo and bacterial mutagenicity of sixteen hydrazine derivatives as related quantitatively to their carcinogenicity. Cancer Res. 41 1469-1482. 

Williams, G.M. (1976a). Carcinogen-induced DNA repair in primary rat liver cell cultures a possible screen for chemical carcinogens. Cancer Lett. (Shannon, Ire.) 1 231-236. Williams, G.M. (1976b). The detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures. Cancer Res. 37 1845-1851. 

Zeiger E. 1987. Carcinogenicity of mutagens Predictive capability of the Salmonella mutagenesis assay for rodent carcinogenicity. Cancer Res 47(5) 1287-1296. 

Milo, G. E., I. Noyes, J. Donahoe, and S. Weisbrode. 1981. Neoplastic transformation of human epithelial cells in vitro after exposure to chemical carcinogens. Cancer Res 41(12 Pt 1 ) 5096—102. 

Numerous sodium compounds are hazardous as carcinogens (cancer-causing) and as toxins (poisons) in plants and animals. On the other hand, we benefit greatly from the many compounds containing the element sodium. We could not live without it. 

Many compounds of carbon, particularly the hydrocarbons, are not only toxic but also carcinogenic (cancer-causing), but the elemental forms of carbon, such as diamonds and graphite, are not considered toxic. 

Cannizzaro reaction An internal oxidation-reduction reaction of aldehydes, carbamide Urea, carcinogenic Cancer causing. 

FA088 Soni, K. B., M. Lahiri, P. Chackradeo, S. V. Bhide, and R. Kuttan. Protective effect of food additives on aflatoxin-induced mutagenicity and hepato-carcinogenicity. Cancer Lett 1997 115(2) 129-133. 

Some fused benzene rings have been implicated as carcinogens (cancer-causing agents). Several of these are found in tobacco smoke. 

Williams, G.M., Elliot, J.M., and Weisburger, J.H. (1973). Carcinoma after malignant conversion in vitro of epithehal-like cells from rat liver following exposure to chemical carcinogens, Cancer Res. 33, 606. 

Brambilla, G, Carlo, P, Finollo, R., Bignone, F.A., Ledda, A. Cajelli, E. (1983) Viscometric detection of liver DNA fragmentation in rats treated with minimal doses of chemical carcinogens. Cancer Res., 43, 202-209... 

Ishikawa, T., Kodama, K., Ide, F. Takayama, S. (1982) Demonstration of in vivo DNA repair synthesis in mouse skin exposed to various chemical carcinogens. Cancer Res., 42, 5216— 5221... 

PNA (polynuclear aromatic) any of numerous complex hydrocarbon compounds consisting of three or more benzene rings in a compact molecular arrangement. Some types of PNA s are known to be carcinogenic (cancer causing). 

TAR/TPM Total particulate matter. An all-purpose term for particle-phase constituents of tobacco smoke, many of which are carcinogenic (cancer-causing) or otherwise toxic. 

Becker, F.F., Ed., Ethology Chemical and Physical Carcinogens, Cancer 1, Plenum Press, New York, 1982, p. 292. 

Ames, B.N., The detection of environmental mutagens and potential carcinogens, Cancer, 1984, chap. 53, pp. 2034-2040. 

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