Cancer carcinogens

Finally, some recognition must be made of the term carcinogen since many of the environmental effects noted in this book can lead to cancer. Carcinogens are cancer-causing substances, and there is a growing awareness of the presence of carcinogenic materials in the environment. A classification scheme is provided for such materials (Table 1.1). The number of substances with which a person... 

Some materials cause genetic changes that can cause cancer (carcinogen), mutation (mutagens), and birth defects (teratogens). These effects are often hard to document due to latency periods and synergisms. 

Cancer Carcinogen or Route Animal or Model Dose... 

Dust irritates the respiratory tract and eyes. Swallowing causes irritation and internal damage. Prolonged exposure causes ulceration, damage to liver and kidneys, and even cancer. Carcinogen as dust. Avoid inhaling dust. Avoid contact with eyes and skin.2 TLV-TWA 0.05 mg/m3.3... 

History of Cancer, Carcinogenicity Testing, and Human Causes of Cancer... 

International Agency for Research on Cancer carcinogen classification 3 (possible human carcinogen, based on a single mouse study employing only one air concentration see details above). 

Formaldehyde is a major contributor to many cases of sick building syndrome. It is a very toxic chemical that is corrosive to the skin, eyes, and the respiratory system. Acute or chronic exposure can result in difficulty breathing and even brief exposures can induce asthmatic reactions in sensitized individuals. 13 Exposures to mixtures of formaldehyde and lipophilic chemicals can result in unanticipated toxic effects. 14 Formaldehyde is an animal carcinogen, a suspected human nasal cancer carcinogen 29 and suspected human leukemogen. 3°1... 

The emphasis in this chapter is on the use of animal tests, or bioassays as they are sometimes called, to identify toxicity. Epidemiology has been important in uncovering the effects of subchronic and chronic exposures to some very important chemicals, including those capable of causing cancer. Carcinogens are a special breed of chronic... 

Cancer. Carcinogenicity of PCBs in humans has been investigated in retrospective occupational studies that evaluated cancer mortality in workers exposed during capacitor manufacturing and repairing, and in case-control studies of the general population that examined associations between cancer and serum or adipose tissue levels of PCBs resulting from environmental exposures. Based on indications of... 

Djordjevic, M.V, S.D. Stellman, and E. Zang Doses of nicotine and lung cancer carcinogens delivered to cigarette smokers J. Natl. Cancer Inst. 92 (2000) 106-111 Dobbins, J.T. Jr Elution column preparation of leaf samples for flame photometry. I. Determination of potassium in tobacco J. Assoc. Off. Agr. Chem. 44 (1961) 360-365. 

Inhalation of radon can lead to lung cancer. Carcinogenic potential may increase by smoking. 

Carcinogen. A substance with the ability to cause cancer Carcinogenicity. Ability to cause cancer. 

International Agency for Research on Cancer, Carcinogenicity of Alkylating Cytostatic Drugs Schmahl, D. Kaldor, J.M., Eds. lARC Scientific Publications No. 78, International Agency for Research on Cancer, Lyon, 1986. 

Carroll, K.K., 1982, Dietary fat and Its relationship to human cancer, "Carcinogens and Mutagens In the Environment, Vol. 1, Food Products," H.F. Stich, ed., CRC Press, Boca Raton, FIorlda. 

Commonly Afflicted Organs and Mortality Rates Causes of Cancer—Carcinogens Chemical Agents Tobacco Alcohol... 

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