Lectins carbohydrate-binding proteins

Kauss, H., and D. J. Bowles Some Properties of Carbohydrate-binding Proteins (Lectins) Solubilized from Cell Walls of Phaseolus aureus. Planta (Berl.) 130, 169 (1976). 

Lectins are carbohydrate-binding proteins involved in cell adhesion and other biologic processes. 

Several carbohydrate-binding proteins have been isolated from Sambucus nigra and two haemagglutinins have been isolated from its bark. Its seeds contain a lectin that is related to the immunological properties of the bark. One of its carbohydrate-binding proteins, called nigrin, is made of two subunits and is reported to cause red blood cells to clump. 5... 

Analytical tools have been developed in order to identify carbohydrate structures as well as carbohydrate-binding proteins and to understand their underlying structure-function relationships of protein-carbohydrate and carbohydrate-carbohydrate interactions lectin arrays [16], glycan microarrays [17, 18], glyco-nanoparticles [19], frontal affinity chromatography [20] and carbohydrate tools for metabolic labeling [21]. 

Gorelik E, Galili U, Raz A. On the role of cell surface carbohydrates and their binding proteins (lectins) in tumor metastasis. Cancer Metast Rev 2001 20 245-277. 

Specific detection of oligosaccharides is possible using lectins, carbohydrate-binding proteins from very different sources. A se-... 

In addition, there is a large group of carbohydrate binding proteins called lectins (from the latin lectus to select).24 174 177 178... 

Lectins are carbohydrate-binding proteins that have been obtained mainly from plants,1128,138 although lectin-like proteins have also been found in micro-organisms and animals,139 including mammals.140 141 Some of the properties of the lectins, and their utility as carbohydrate-specific reagents have been reviewed.1128,138,138... 

The use of neoglycoproteins as affinants can be extended to the purification of such other classes of carbohydrate-binding protein as lectins, glycosylhydrolases, and glycosyltransferases. Some of the procedures that have been developed to prepare neoglycoproteins have been adapted to attach carbohydrates directly to Sepharose11,23,89,135, 177,178 and (2-aminoethyl)-Bio-Gel.59,81,87 These materials have been... 

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