Calcium therapy

Dextrose and insulin (with or without sodium bicarbonate) are typically given at the time of calcium therapy in order to redistribute potassium into the intracellular space. Dextrose 50% (25 g in 50 mL) can be given by slow IV push over 5 minutes or dextrose 10% with 20 units of regular insulin can be given by continuous TV infusion over 1 to 2 hours. The onset of action for this combination is 30 minutes and the duration of clinical effects... 

Applications of cation and anion resins are varied and include purification of sugar, identification of drugs and biomacromolecules, concentration of uranium, calcium therapy to help increase the amount of calcium in our bones (i.e., increase the bone density), and use as therapeutic agents for the control of bile acid and gastric acidity. In the latter use, a solid polyamide (Colestid) is diluted and taken with orange juice, which facilitates removal of bile acids from the body. This removal helps the body to produce more bile acid from cholesterol, thus effectively reducing the cholesterol level. 

Fracture In Paget patients, treatment regimens of etidronate exceeding the recommended daily maximum dose of 20 mg/kg or continuous administration for periods greater than 6 months may be associated with an increased risk of fracture. Hypocalcemia Hypocalcemia has occurred with pamidronate therapy. Rare cases of symptomatic hypocalcemia (including tetany) occurred during pamidronate treatment. If hypocalcemia occurs, consider short-term calcium therapy. Hypocalcemia must be corrected before therapy initiation with alendronate and risedronate. Also effectively treat other disturbances of mineral metabolism (eg, vitamin D deficiency). 

The basis of the treatment of fluoride poisoning is intravenous or intramuscular calcium therapy [61,62]. 

Tuberculosis Antihypertensives Antidepressants Vitamins Calcium therapy Antiepileptics Antihelmintics Antifungals... 

Calcium therapy. Patients are routinely given calcium-containing solutions during cardiac surgery, and may have transient hypercalcaemia afterwards. 

C. Calcium antagonist poisoning. Start with doses as described above. High-dose calcium therapy has been reported effective in some oases of severe calcium channel blocker overdose. As much as 12 g of calcium chloride has been given over 2 hours. Administer calcium as multiple boluses (eg, 1 g every 10-20 minutes) or as a continuous infusion (eg, 20-50 mg/kg/h). 

Dalton BR, Zuege DJ, Shahpori R, Laupland KB. Concomitant ceftriaxone and high-concentration intravenous calcium therapy in adult critical care patients a matched cohort study. Aim Pharmacother 2010 44(7-8) 1158-63. 

Gluconic acid calcium salt In calcium therapy In animal nutrition Heaney et al. (1977) and Perkins (1978)... 

Vitamin D withdrawal is an obvious treatment for D toxicity (219). However, because of the 5—7 d half-life of plasma vitamin D and 20—30 d half-life of 25-hydroxy vitamin D, it may not be immediately successful. A prompt reduction in dietary calcium is also indicated to reduce hypercalcemia. Sodium phytate can aid in reducing intestinal calcium transport. Calcitonin glucagon and glucocorticoid therapy have also been reported to reduce semm calcium resulting from D intoxication (210). 

Heterocycles, calcium channels blockers, as auxiliary agents in resistant tumor therapy 97YZ455. 

Dihydropyridines not only are intermediates for the synthesis of pyridines, but also are themselves an important class of N-heterocycles an example is the coenzyme NADH. Studies on the function of NADH led to increased interest in the synthesis of dihydropyridines as model compounds. Aryl-substituted dihy-dropyridines have been shown to be physiologically active as calcium antagonists. Some derivatives have found application in the therapy of high blood pressure and angina pectoris. For that reason the synthesis of 1,4-dihydropyridines has been the subject of intensive research and industrial use. The Hantzsch synthesis has thus become an important reaction. 

When alendronate and risedronate are administered, serum calcium levels are monitored before, during, and after therapy. 

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