Body temperature, reduced

Serotonin 5-HTia receptor CNS, endocrine Decrease in body temperature, reduced REM sleep... 

Other symptoms may Include low blood pressure, abnormal breathing, reduced body temperature, reduced body pH, convulsions, collapse and death. 

Acetylsalicylic acid is largely used in medicine as an analgesic (t.e., for removing pain) and as an antipyretic (i.e., for reducing the body temperature). 

Besides behavior and blood pressure, catecholamine neurons also have important roles in other brain functions. Regulation of neuroendocrine function is a well-known action of catecholamines for example, DA agonists reduce semm prolactin concentration, especially in conditions of hypersecretion. Ingestive behavior can be modulated by brain catecholamines, and some appetite-suppressing dmgs are beheved to act via catecholaminergic influences. Catecholamines also participate in regulation of body temperature. 

Humans seek and want thermal comfort, even at work in industrial settings. Clothing, activities, posture, location, and shelter are chosen, adjusted, altered, and sought consciously and unconsciously to reduce discomforts and enable us to focus more on the other tasks of life. Discomfort can contribute to mistakes, productivity decreases, and industrial accidents. " Thermal discomfort results from the physiological strain of thermoregulation. The strain can be in the form of altered body temperatures, sweating and excessive skin moisture, muscle tension and stiffness, shivering, and loss of dexterity. A small... 

Heat stroke A serious acute condition caused by the elevation of the body temperature above the danger level. Symptoms can include redness of the face, reduced sweating, erratic behavior, confusion, dizziness, collapse, or unconsciousness. 

Maytenus spp. Chuchuara or chuchuhuasha from Peru contains an amorphous alkaloid which lowers body temperature and reduces blood pressure. (Raymond-Hamet and Colas, Bull. Acad. M d., 1935,114,139 Perrot, MUlat and Colas, Bull. Sci. Pharmacol., 1937, 44, 325.)... 

The salicylates include aspirin (acetylsalicylic acid) and related drugp, such as magnesium salicylate and sodium salicylate. The salicylates have analgesic (relieves pain), antipyretic (reduces elevated body temperature), and anti-inflammatory effects. All the salicylates are similar in pharmacologic activity however, aspirin has a greater anti-inflammatory effect than the other salicylates. Specific salicylates are listed in the Summary Drug Table Nonnarcotic Analgesics Salicylates and Nonsalicylates. 

Do not abruptly discontinue use of the antiparkinsonism drugs Neuroleptic malignant-like syndrome may occur when the antiparkinsonism drugs are discontinued or the dosage of levodopa is reduced abruptly. The nurse carefully observes the patient and reports the following symptoms muscular rigidity, elevated body temperature, and mental changes... 

TRPVl also plays a central role in intercellular pro-inflammatory feedback loops. An important example is mast cells and sensory nerves. Mast cells release tryptase that, in turn, activates the protease-activated receptor PAR-2 activation of PAR-2 then opens TRPVl via PKC [50]. In keeping with this, PAR-2 agonists reduce the heat activation threshold of TRPVl from 42 °C to below body temperature [51]. Excited nerve endings release SP that, as a positive feedback, binds to neurokinin NKl receptors on mast cells. Mast cells also express TRPVl [52]. Consequently, endovanilloids can act in concert to stimulate mast cells and activate capsaicin-sensitive nerve endings. Of relevance is the finding that PAR-2 is up-regulated in the bladder during experimental cystitis [53]. 

A new product being developed currently is a mattress to treat hypoxia (lack of oxygen) in newborn babies. It is known that reducing the body temperature of the new born has a positive effect therefore they are treated with cold towels, medicine, chilled rooms to keep the temperature. This treatment could be substituted by the treatment with a PCM mattress, thereby optimizing and prolonging the temperature regulating effect. 

Heat can be a problem for professional athletes both in training and at competition. Heat can also be a problem for other people like elderly people, people with some diseases and children. If the body-temperature can be reduced most people would feel more comfortable, perform better, be able to keep concentrate better and for a longer time and the risks of dehydration and fatigue is reduced. New products to address this problem were developed, such as wrist-cooler, a neck-cooler, a cap and a vest (Figure 166). All these... 

Melega, W.R, Lacan, G., Harvey, D.C., Huang, S.C., Phelps, M.E. Dizocilpine and reduced body temperature do not prevent methamphetamine-induced neurotoxicity in the vervet monkey [1 lC]WfN 35,428-positron emission tomography studies. Neurosci. Eett. 258 17, 1998. 

Acute physiological responses to opiate administration occur rapidly and include constricted pupils, decreased pulse rate, reduced body temperature, slowed respiration rate and impaired reflexes. In addition, there is a marked slowing of the digestive system through an altering of the tonus and motility of the stomach and intestines, allowing for greater water absorption. This last effect is not subject to tolerance, and constipation is a common side effect even for chronic users. Indeed, some report that this is the worst side effect of opiate use. 

---