Biomimetics adhesive

Q.M. (2010) Ultra-low fouling and functionalizable zwitterionic coatings grafted onto SiO2 via a biomimetic adhesive group for sensing and detection in complex media. Biosensors cf Bioelectronics, 25 (10), 2276-2282. 

Thus, studying the adhesive characteristics and the adhesion mechanisms of aquatic organisms is a promising approach toward the development of future biomimetic adhesives with an extended spectrum of properties, which may find application in the medical and dental or technical fields. Further understanding of underwater adhesion mechanisms in biological systems wiU also lead to con-... 

A second goal of this chapter is to provide a summary of recent efforts to develop biomimetic adhesive S3 tems. A growing number of researchers are motivated to develop biomimetic adhesive S3 tems that are inspired by their natural counterparts, believing that the exceptional adhesive properties... 

G. V. Shah and M. Sitti, Modeling and Design of Biomimetic Adhesives Inspired by Gecko Foot-Hairs, in IEEE International Conference on Robotics and Biomimetics. 2004. 

Biomimetics is an important strategy for the fabrication of modern biomaterials that provides solutions which closely resemble those of living systems. In the area of biomimetic supramolecular chemistry, a surface-grafted PMOEP polymer has recently been found to impart mesoporous silica with switchable ion channel transport properties. This was enabled by the dual protonation and Ca chelation ability of the polymer phosphate groups. A series of studies made use of PMAEP-based copolymers in the fabrication of biomimetic adhesives which were inspired by the sandcastle worm that produces peptide polyelectrolytes rich in phosphorylated serine. These adhesives were aimed at providing molecular solutions to... 

Li, G. Chenga, G. Xue, H. Chena, S. Zhang, F Jiang, S. Ultra low fouling zwitterionic polymers with a biomimetic adhesive group. Biomaterials 2008, 29, 4592-4597. 

Numerous biomimetic adhesives inspired by mussels haven been validated by in vitro or in vivo testing. Examples are adhesive-coated scaffolds tailor-made for the vascular system that promote cell proliferation (Ku and Park, 2010), adhesives for the immobilization of pancreatic transplants on the liver surface (Bilic et al., 2010), adhesive-coated biological meshes (eg, for hernia repair Murphy et al., 2010), scaffolds (eg, for Achilles tendon repair Brodie et al., 2011) or titanium implants (eg, for osteoblast proliferation promotion Hwang et al., 2010), and sealant for fetal membrane repair (Brubaker et al., 2010). 

Bitton, R., Bianco-Peled, H., 2008. Novel biomimetic adhesives based on algae glue. Macromol. Biosci. 8, 393—400. 

Jo, S.H., Sohn, J.S., 2014. Biomimetic adhesive materials containing cyanoacryl group for medical application. Molecules 19, 16779—16793. 

B.P., Dalsin, J.L., Messersmith, P.B., 2006. Biomimetic adhesive polymers based on mussel adhesive proteins. In Biological Adhesives. Springer. 

To engineer bioactivity in materials we now commonly incorporate biologically motivated, biomimetic adhesion-promoting sites. Most frequently we also add factors, such as growth factors, to promote or suppress growth. It is also now established that we can, at least in part, mimic the less specific interactions of, for example, heparin, in this case with polyelectrolytes, in biomaterials design. 

Figure 10.4 Diversity of chemistiy structures utilized to create biomimetic adhesive polymers. Catechol side chain (A) modification alters its interfacial binding strength and reactivity. Substitution can be achieved by replacing -H at the para position with chloro-(B), nitro- (C) and hydrojyl (D) groups or a hydro)yl group at the meta position (E). The benzene ring can be substituted with a pyridine group (F). Linking the catechol with a polymer can be achieved via reaction of the amino acid (G), acid (H), or amine (I) groups. Catechol modified with a bromide propionamide Initiator to initiate polymerization (J) or functionalized with polymerizable methacrylamide (K), vinyl (L), and M-carboxyanhydride (NCA, M) groups.

Li, G., Xue, H., Gao, C., Zhang, R, Jiang, S. (2010). Nonfouling polyampholytes from an ion-pair comonomer with biomimetic adhesive groups. Macromolecules, 43, 14-16. 

First-Generation Biomimetic Adhesive Supports Short Oligopeptides. . . 180... 

Biomimetic adhesives are synthetic adhesives designed to closely mimic the molecular structure and mechanisms of adhesion found in nature. Bioinspired adhesives are synthetic adhesives whose design is inspired in biological concepts, mechanisms, functions, and design features. The aim is not to emulate any particular biological architecture or system, but to use such knowledge as a source of guiding principles and ideas. 

Bogue R (2008) Biomimetic adhesives a review of recent developments. Assembly Automation 28(4) 282-288... 

Lee BP, Dalsin JL, Messersmith PB (2006) Biomimetic adhesives polymers based on mussel adhesive proteins. In Smith AM, Qillow JA (eds) Biological adhesives. Springer, Berlin... 

Bitton R, Bianco-Peled H (2008) Novel biomimetic adhesives based on algae glue. Macromol Biosci 8 393-400 Braunwald NS, Gay W, Tatooles CJ (1966) Evaluation of crosslinked gelatin as a tissue adhesive and hemostatic agent an experimental study. Surgery 60 857-861... 

There are different types of commercially available tissue adhesives, classified into three categories natural or biological, synthetic and semisynthetic, and biomimetic. The biological tissue adhesives such as fibrin glues and collagen are quite effective in select applications. Their drawbacks are high cost and limited availability. The action of biomimetic adhesives is based on... 

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