Biomedical analysis

Meyerhoff, M. E. Fu, B. Bakker, E. et al. Polyion-Sensitive Membrane Electrodes for Biomedical Analysis, Anal. Chem. 1996, 68, 168A-175A. [Pg.541]

All main aspects of analytical and bioanalytical sciences is covered by the conference program. AC CA-05 consists of 12 invited lectures and seven symposia General Aspects of Analytical Chemistry, Analytical Methods, Objects of the Analysis,. Sensors and Tests, Separation and Pre-concentration, Pharmaceutical and Biomedical Analysis, History and Methodology of Analytical Chemistry. Conference program includes two special symposia Memorial one, dedicated to Anatoly Babko and Analytical Russian-Germany-Ukrainian symposium (ARGUS-9). [Pg.3]

In biomedical analysis, LC-LC has been used most extensively and successfully in the heart-cut mode for the analysis of drugs and related compounds in matrices Such as plasma, serum or urine. Table 11.1 gives an overview of analytes in biological matrices which have been determined by heart-cut LC-LC systems. A typical example of such an approach is the work of Eklund et al. (16) who determined the free concentration of sameridine, an anaesthetic and analgesic drug, in blood plasma... [Pg.254]

Figure 11.5 Chromatograms of plasma samples obtained with fully automated on-line SPE-LC (a) dmg-ffee human plasma (b) human plasma spiked with omeprazole (100 ng/ml) and phenacetin (internal standard 1000 ng/ml). Reprinted from Journal of Pharmaceutical and Biomedical Analysis, 21, G. Garcia-Encina et al., Validation of an automated liquid chromatograpliic method for omeprazole in human plasma using on-line solid-phase exti action, pp. 371 - 382, copyright 1999, with permission from Elsevier Science.

LCEC has become a widely used analytical technique for biomedical analysis. Several reports appear each month deairibing new LCEC analyses or reporting results obtain-with LCEC. While space does not permit a complete review of all bitwhemical applications, this section will consider applications of LCEC to general classes of compounds to provide an overview of the uses of this technique. For a thorough survey of the literature, a bibliography of LCEC applications is available... [Pg.25]

Solsky, R. L. Ion-Selective Electrodes in Biomedical Analysis, in CRC Critical Reviews in Analytical Chemistry 14, 1 (1982)... [Pg.41]

Wainer, I.W. (1989). The application of achiral/chiral coupled-column high-performance liquid chromatography to biomedical analysis. J. Pharm. Biomed. Anal. 7, 1033-1038. [Pg.344]

Vo-Dinh T., Stokes D.L., Griffin G.D., Volkan M., Kim U.J., Simon M.I., Surface-enhanced Raman scattering (SERS) method and instmmentation for genomics and biomedical analysis, / Raman Spectrosc. 1999 30 785-793. [Pg.254]

S. Ulrich, Solid phase microextraction in biomedical analysis, J. Chromatogr. A, 902, 167 194... [Pg.299]

Ion-selective electrode research for biomedical analysis is no longer the relatively narrow, focused field of identifying and synthesizing ionophores for improved selectivity and the integration of ion-selective electrodes into clinical analyzers and portable instruments. These efforts have matured now to such an extent that they can teach valuable lessons to other chemical sensing fields that are just emerging technologies. [Pg.131]

This field is therefore at an exciting stage. Ion-selective electrodes have a proven track record in terms of clinical and biomedical analysis, with a well-developed theory and a solid history of fundamental research and practical applications. With novel directions in achieving extremely low detection limits and instrumental control of the ion extraction process this field has the opportunity to give rise to many new bioana-lytical measurement tools that may be truly useful in practical chemical analysis. [Pg.132]

General books [213-217], chapters [218], and reviews were published in the 1980s reporting the suitability of CL and BL in chemical analysis [219-222], the specific analytical applications of BL [223], the CL detection systems in the gas phase [224], in chromatography [225, 226], the use of different chemiluminescent tags in immunoassay, and applications in clinical chemistry [227-232] as well as the applications of CL reactions in biomedical analysis [233]. [Pg.32]

Geng, D., Shankar, G., Schantz, A., Rajadhyaksha, M., Davis, H., and Wagner, C. 2005. Validation of immunoassays used to assess immunogenicity to therapeutic monoclonal antibodies. Journal of Pharmaceutical and Biomedical Analysis 39, 364-375. [Pg.202]

The technical elements of biomedical analysis are not the focus of this paper however a brief mention of the areas identified by the OPCW expert group is warranted. A summary of the conclusions as they relate to these areas is presented in table 1. [Pg.127]

Dyson RM, Helg AG, Meisenbach M, Allmendinger T (2000) In situ observation of the progress of a large-scale on-bead reaction. 11th International Symposium on Pharmaceutical and Biomedical Analysis, Basle, Switzerland, p 007... [Pg.202]

A newer addition is in-tube SPME that makes use of an open capillary device and can be coupled online with GC, HPLC, or LC/MS. All these techniques and their utilization in pharmaceutical and biomedical analysis were recently reviewed by Kataoka.45 Available liquid stationary fiber coatings for SPME include polydimethylsiloxane (PDMS) and polyacrylate (PA) for extracting nonpolar and polar compounds, respectively. Also in use for semipolar compounds are the co-polymeric PDMS-DVB, Carboxen (CB)-PDMS, Carbowax (CW)-DVB, and Carbowax-templated resin (CW-TPR). A few examples of in-tube SPME extractions from biological matrices are shown in Table 1.19 and drawn from Li and coworkers.166... [Pg.53]

D.A. Wells, Progress in Pharmaceutical and Biomedical Analysis, Vol. 5, Elsevier, Amsterdam, 2003. [Pg.69]

W. R. G. Baeyens, D. De Keukelaire, and K. Korkidis (Eds.), Luminescence Techniques in Chemical and Biomedical Analysis, Marcel Dekker, New York (1991). [Pg.329]

Fekete S. Rudaz S. Fekete J. Guillaume D. Analysis of recombinant monoclonal antibodies by RPLC Toward a generic method development approach. Journal of Pharmaceutical and Biomedical Analysis, 2012, 70, 158-168. [Pg.67]

Ajayakumar P.V. Chanda D. Pal A. Singh M.P. Samad A. FT-NIR spectroscopy for rapid and simple determination of nimesulide in rabbit plasma for pharmacokinetic analysis. Journal of Pharmaceutical and Biomedical Analysis, 2012, 58 (1), 157-162. [Pg.71]

S.M. Lunte and D.M. Radzik (Eds.), Pharmaceutical and Biomedical Applications of Capillary Electrophoresis, Progress in Pharmaceuical and Biomedical Analysis, Vol. 2, Elsevier Science, Oxford, 1996. [Pg.222]

Espinose-Maansilla, A., Duran-Meras, I. Salinas, E., 1998, Journal of Pharmaceutical and Biomedical. Analysis, 17, 1325-1334. [Pg.311]

Vrije Universiteit Brussel - VUB, Dept. Pharmaceutical and Biomedical Analysis, Laarbeeklaan 103, B-l 090 Brussels, Belgium... [Pg.447]

Y. Vander Heyden (447) Vrije Universiteit Brussel, Faculty of Medicine and Pharmacy Dept. Pharmaceutical and Biomedical Analysis, Laarbeeklaan 103 B-1090, Brussels, Belgium Qingxi Wang (379) Pharmaceutical Research Development, Merck Research Laboratories, West Point, PA 19486 USA Mieng-Hua Wann (569) Purdue Pharma, 444 Saw Mill River Rd, Ardsley, NY 10502 USA... [Pg.678]

As polarity plays an important role in the analysis of small organic compounds such as pharmaceuticals (most organic compounds can be neutral), the introduction of MEKC resulted in a boom of applications in this area. In biomedical analysis with CE, MEKC is the technique of choice for the analysis of drugs in pharmaceutical preparations or in body fluids. Several groups of drugs have been analyzed with considerable success. A typical... [Pg.36]

Amini, A. (2001). Recent developments in chiral capillary electrophoresis and applications of this technique to pharmaceutical and biomedical analysis. Electrophoresis 22(15), 3107-3130. [Pg.164]

Smith, N. W., and Evans, M. B. (1994). Capillary zone electrophoresis in pharmaceutical and biomedical analysis./. Pharm. Biomed. Anal. 12, 579—611. [Pg.308]

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