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Biologies toxicities

Thompson, D. C. Thompson, J. A. Sugumaran, M. Moldeus, P. Biological toxical consequences of quinone methide formation. Chem.-Biol. Interact. 1993, 86, 129-162. [Pg.288]

There is a good correlation between organic matters and contents of various Cd forms. Organic matters can make Cadmium activate in the soils and lead to, biological toxicity. [Pg.96]

This study is an overview focused on the application of the main analytical strategies based on chemical analysis and biological toxicity assays for pesticides, to be used as a combined approach for the evaluation of pesticides in wastewaters. [Pg.54]

Carbon tetrachloride is a solvent that is chemically inert, highly resistant to oxidation, but biologically toxic. Despite its chemical stability, P450 is able to convert carbon tetrachloride to several reactive species. Reduced P450 transfers an electron to chloride leading to the elimination of a chloride anion and the generation of the reactive trichloromethyl radical (10). Trichloromethyl radical can undergo a second one-electron reduction to... [Pg.112]

Measurement or estimation of health impacts under TSCA would be premature, since relatively little has been done to regulate new or existing chemicals that could result in health benefits. The principal exception to this generalization is the ban on aerosol uses of CFCs, whose chronic effects on human health derive from their environmental impact rather than direct biological toxicity. Compared with other environmental laws, such as the Clean Air Act, the regulatory accomplishments of TSCA are somewhat insubstantial. [Pg.178]

Enhanced resistance to biologically toxic or bacteriostatic substances ... [Pg.251]

Biological toxicity tests are widely used for evaluating the toxicants contained in the waste. Most toxicity bioassays have been developed for liquid waste. Applications of bioassays in wastewater treatment plants fall into four categories [19]. The first category involves the use of bioassays to monitor the toxicity of wastewaters at various points in the collection system, the major goal being the protection of biological treatment processes from toxicant action. [Pg.17]

Preference is obviously for a simple chemical assay for PSP. Unfortunately the more specific the chemical test, the narrower is the window of compounds it can assay. The Paralytic Shellfish Poison is not just Saxitoxin (STX) as originally believed, but is a mixture of compounds closely related to STX Q) and the mix varies widely with location and with time ( ). It would seem, therefore that a chemical assay should determine at least the ratios of the several compounds, and that the relative toxicity of each of the compounds must be known. An effective assay must evaluate the actual biological toxicity of the shellfish being tested. For the chemical assay this requires the summated toxicity of all the... [Pg.193]

Siloxanes are the most extensively used synthetic biomaterial due to several reasons such as flexibility, chemical and biological inertness, low capacity to bring about blood clotting, overall low degree of biological toxicity, and good stability within biological environments. [Pg.597]

Absorption is necessary for the chemical to exert a systemic biological/toxic effect and involves crossing membranes. Membranes are semipermeable phospholipid/protein bilayers. The phospholipids and proteins are of variable structure, and the membrane is selectively permeable. The physicochemical characteristics of foreign molecules that are important include size/shape, lipid solubility, structure, and charge/polarity. [Pg.71]

The above factors should be borne in mind when attempts are made to reduce a complex biological toxic reaction in vivo to a simple test using cultured cells in vitro. The latter may prove useful, but results derived using them should be extrapolated to man with great caution. [Pg.120]

Ahtiainen, J., Nakari, T. and Silvonen, J. (1996) Toxicity of TCF and ECF pulp bleaching effluents assessed by biological toxicity tests, in M.R. Servos, K.R. Munkittrick, J.Ef. Carey and G.J. Van Der Kraak (eds.), Environmental Fate and Effects of Pulp and Paper Mill Effluents, St-Lucie Press, FL, pp. 33-40. [Pg.34]

Aluminium is an environmentally abundant element and has no known biological function in living cells. On the other hand, A1 exhibits biological toxicity as demonstrated in experimental models." " Intake and output of aluminium for the healthy population from various sources, biological monitoring of occupational aluminium exposure in serum and speciation analysis of the amount and composition of A1 species with high and low molecular masses, have been reviewed by several groups. Besides the use of mass spectrometric and non-mass spectrometric techniques (e.g., ETAAS after separation of human serum proteins ) ESI-MS-MS analysis has also been performed to identify the A1 species. [Pg.347]

Early studies showed a correlation between the biological toxicities of Cry proteins and their abilities to bind to midgut brush border membrane vesicles (BBMV) of susceptible larvae [69-71]. Toxin binding to membrane is a two-stage process involving reversible and irreversible steps, with irreversible binding generally associated with membrane insertion [69,70,72,73]. [Pg.219]

The safety of a lipid product will in part be a reflection of 1) the purity of the compounds administered 2) biological toxicity of the basic chemical ingredients and 3) reactions to structural presentations of the lipid. Noncompendial lipid materials will necessitate significant toxicology testing. [Pg.985]

At least 11 metals are biologically toxic, as shown in Table I along with their threshold limit values (1,2,3) arsenic, beryllium, bismuth, cadmium, mercury, nickel, lead, antimony, selenium, tin, and vanadium. For these and other metals, the biological toxicity for long-term, low-level exposures is not known. Other metals such as manganese and iron are... [Pg.147]

Less than 0.1 pm in diameter, ultra-fine particles (UFPs). These particles demonstrate very high deposition in human alveoli and have very high surface areas (relative to mass) that can lead to biological toxicity. These particles are small enough to penetrate protective membranes and enter the bloodstream, from where they are deposited all over the body. [Pg.487]


See other pages where Biologies toxicities is mentioned: [Pg.49]    [Pg.15]    [Pg.735]    [Pg.62]    [Pg.236]    [Pg.39]    [Pg.54]    [Pg.142]    [Pg.347]    [Pg.168]    [Pg.170]    [Pg.23]    [Pg.55]    [Pg.55]    [Pg.370]    [Pg.59]    [Pg.1236]    [Pg.438]    [Pg.1296]    [Pg.1]    [Pg.142]    [Pg.4897]    [Pg.147]    [Pg.148]    [Pg.124]    [Pg.2452]    [Pg.2564]    [Pg.607]    [Pg.321]    [Pg.231]    [Pg.169]   
See also in sourсe #XX -- [ Pg.467 , Pg.468 , Pg.469 ]




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Biologic systems mercury toxicity

Biological Activity and Mode of Toxic Action

Biological Effects and Toxicity

Biological Factors Affecting Toxicity

Biological Strategies Against Oxygen Toxicity Antioxidants, Etc

Biological action toxic

Biological activity toxicity studies

Biological and Toxic Weapons

Biological effect, toxicity measurement

Biological hazards from toxic materials

Biological markers, lead toxicity

Biological toxicity tests

Biologies toxicity mechanisms

Cell biology, toxic

Metal biologically toxic

RECOGNIZING LABORATORY HAZARDS TOXIC SUBSTANCES AND BIOLOGICAL AGENTS

Selective toxicity biological concept

Toxic materials biological

Toxic metals biological effects

Toxicants biological entry routes

Toxicants elimination, from biological systems

Toxicity biological activity

Toxicity biological availability

Toxicity studies biological data

Toxicity study evaluation biological significance

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