Bioconjugation, polymer

Knoop RJI, de Geus M, Habraken GJM, Koning CE, Menzel H et al (2010) Stimuli responsive peptide bioconjugated polymer nanoparticles. Macromolecules 43 4126-4132... 

Finally, azide-aUcyne click chemistry has been used to attach Choi, modified with a propargyl group, to poly(3-azidomethyl-3-methyloxetane), prepared by a cationic ROP [177]. High conversion of the azide groups is achieved with excess of Chol-propargyl. As mentioned, there are a number of methods to attach Choi (and/or menthol), with OH functionalities, to synthetic polymers so as to combine the properties of the two. The same synthetic methods should be applicable to other (functional) terpenes, which would certainly expand the family of terpene-based bioconjugate polymers. 

E. Arce, P. M. Nieto, V. Diaz, R. Garcia Castro, A. Bemad, and J. Rojo, Glycodendritic structures based on Boltom hyperbranched polymers and their interactions with Lens culinaris lectin, Bioconjug. Chem., 14 (2003) 817-823. 

Haensler, J., and Szoka Jr., F.C., Polyamidoamine cascade polymers mediate efficient transfection of cells in culture, Bioconjugate Chemistry, 1993, 4, 372-379. 

Bellocq NC, Pun SH, Jensen GS, Davis ME (2003) Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 14 1122-1132... 

Foster S, Duvall CL, Crownover EF et al (2010) Intracellular delivery of a protein antigen with an endosomal-releasing polymer enhances CD8 T-cell production and prophylactic vaccine efficacy. Bioconjug Chem 21 2205-2212... 

Veronese FM, Schiavon O, Pasut G, Mendichi R, Andersson L, Tsirk A, Ford J, Wu G, Kneller S, Davies J, Duncan R (2005) PEG-doxorubicin conjugates influence of polymer structure on drug release, in vitro cytotoxicity, biodistribution, and antitumor activity. Bioconjug Chem 16 775-784... 

Kumar, P., Agarwal, S.K., and Gupta, K.C. (2004) N-(3-Trifluoroethanesulfonyloxypropyl)-anthraqui-none-2-carboxamide a new heterobifunctional reagent for immobilization of biomolecules on a variety of polymer surfaces. Bioconjugate Chem. 15, 7-11. 

Slinkin, M.A., Klibanov, A.L., and Torchilin, V.P. (1991) Terminal-modified polylysine-based chelating polymers Highly efficient coupling to antibody with minimal loss in immunoreactivity. Bioconjugate Chem. 2, 342-348. 

Trubetskoy, V.S., Narula, J., Khaw, B.A., and Torchilin, V.P. (1993) Chemically optimized antimyosin Fab conjugates with chelating polymers Importance of the nature of the protein-polymer single site covalent bond for biodistribution and infarction localization. Bioconjugate Chem. 4, 251-255. 

Yan, M., Cai, S.X., Wybourne, M.N., and Keana, J.F.W. (1994) N-Hydroxysuccinimide ester functionalized perfluorophenyl azides as novel photoactivatable heterobifunctional cross-linking reagents. The covalent immobilization of biomolecules to polymer surfaces. Bioconjugate Chem. 5, 151-157. 

Hong S, Leroueil PR, Janus EK, et al. (2006). Interaction of polycationic polymers with supported lipid bilayers and cells nanoscale hole formation and enhanced membrane permeability. Bioconjug. Chem. 17 728-34. 

T. Shimoboji, E. Larenas, T. Fowler, A. S. Hoffman, and P. S. Stayton, Temperature-induced switching of enzyme activity with smart polymer-enzyme conjugates. Bioconjugate CherrL 14 (3), 517(2003). 

Wolfert MA, Dash PR, Nazarova O, et al. Polyelectrolyte vectors for gene delivery influence of cationic polymer on biophysical properties of complexes formed with DNA. Bioconjug Chem 1999 10(6) 993-1004. 

Maeda, H., Seymour L. W., and Miyamoto, Y. Conjugates of anticancer agents and polymers advantages of macromolecular therapeutics in vivo. Bioconjugate Chem., 1992, 3, 351-361. 

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