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Gene delivery targeting

Bone tissue Gene delivery Targeted delivery of antiarthritic drug with Chandrasekar... [Pg.969]

Trepel M, Grifman M, Weitzman MD et al. Molecular adaptors for vascular-targeted adenoviral gene delivery. Hum Gene Ther 2000 11 1971-1981. [Pg.530]

Lemkine GF, Goula D, Becker N, Paleari L, Levi G, Demeneix BA (1999) Optimisation of polyethylenimine-based gene delivery to mouse brain. J Drug Target 7 305-312... [Pg.21]

Kircheis R, Schuller S, Brunner S, Ogris M, Heider KH, Zauner W, Wagner E (1999) Polycation-based DNA complexes for tumor-targeted gene delivery in vivo. J Gene Med 1 111-120... [Pg.22]

Fisher KD, Ulbrich K, Subr V, Ward CM, Mautner V, Blakey D, Seymour LW (2000) A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression. Gene Ther 7 1337-1343... [Pg.22]

Hughes JA, Rao GA (2005) Targeted polymers for gene delivery. Expert Opin Drug Deliv 2 145-157... [Pg.23]

Boeckle S, Wagner E (2006) Optimizing targeted gene delivery chemical modification of viral vectors and synthesis of artificial virus vector systems. AAPS J 8 E731-E742... [Pg.23]

Bellocq NC, Pun SH, Jensen GS, Davis ME (2003) Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. Bioconjug Chem 14 1122-1132... [Pg.23]

Koppu S, Oh YJ, Edrada-Ebel R, Blatchford DR, Tetley L, Tate RJ, Dufes C (2010) Tumor regression after systemic administration of a novel tumor-targeted gene delivery system carrying a therapeutic plasmid DNA. J Control Release 143 215-221... [Pg.24]

Chiu SJ, Ueno NT, Lee RJ (2004) Tumor-targeted gene delivery via anti-HER2 antibody (trastuzumab, Herceptin) conjugated polyethylenimine. J Control Release 97 357-369... [Pg.24]

Moffatt S, Wiehle S, Cristiano RJ (2005) Tumor-specific gene delivery mediated by a novel peptide-polyethylenimine-DNA polyplex targeting aminopeptidase N/CD13. Hum Gene Ther 16 57-67... [Pg.25]

Nishikawa M, Yamauchi M, Morimoto K, Ishida E, Takakura Y, Hashida M (2000) Hepato-cyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi- functional gene delivery system. Gene Ther 7 548-555... [Pg.25]

Huang R, Ke W, Liu Y, Jiang C, Pei Y (2008) The use of lactoferrin as a ligand for targeting the polyamidoamine-based gene delivery system to the brain. Biomaterials 29 238-246... [Pg.25]

Elfinger M, Maucksch C, Rudolph C (2007) Characterization of lactoferrin as a targeting ligand for nonviral gene delivery to airway epithelial cells. Biomaterials 28 3448-3455... [Pg.26]

Interest in dendritic polymers (dendrimers) has grown steadily over the past decade due to use of these molecules in numerous industrial and biomedical applications. One particular class of dendrimers, Starburst polyamidoamine (PAMAM) polymers, a new class of nanoscopic, spherical polymers that appears safe and nonimmunogenic for potential use in a variety of therapeutic applications for human diseases. This chapter will focus on investigations into PAMAM dendrimers for in vitro and in vivo nonviral gene delivery as these studies have progressed from initial discoveries to recent animal trials. In addition, we will review other applications of dendrimers where the polymers are surface modified. This allows the opportunity to target-deliver therapeutics or act as competitive inhibitors of viral or toxin attachment to cells. [Pg.441]

D. P. McIntosh, X.-Y. Tan, P. Oh, and J. E. Schnitzer. Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo A pathway to overcome cell barriers to drug and gene delivery. Proc. Natl. Acad. Sci. USA 99 1996-2001 (2002). [Pg.613]


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See also in sourсe #XX -- [ Pg.951 ]




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