Beta-proteins

DM Standley, JR Gunn, RA Friesner, AE McDermott. Tertiary structure prediction of mixed alpha/beta proteins via energy minimization. Proteins 33 240-252, 1998. 

SAUNDERS P T, SHARPE R M, WILLIAMS K, MACPHERSON S, URQUART H, IRVINE D S, MILLAR M R (2001) Differential expression of oestrogen receptor alpha and beta proteins in the testes and male reproductive system of human and non-human primates. Mol Hum Reprod. 7 227-36. 

Davis, J.B., McMurray, H.F. and Schubert, D. (1992). The amyloid beta-protein of Alzheimer s disease is chemotactic for mononuclear phagocytes. Biochem. Biophys. Res. Commun. 189, 1096-1100. 

Harper JD, Lieber CM, Lansbury PT Jr. Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer s disease amyloid-beta protein. Chem Biol 1997 4 951-959. 

Lomakin A, Teplow DB, Kirschner DA, Benedek GB. Kinetic theory of fibrillogenesis of amyloid beta-protein. Proc Natl Acad Sci USA 1997 94 7942-7947. 

Lomakin A, Chung DS, Benedek GB, Kirschner DA, Teplow DB. On the nucleation and growth of amyloid beta protein fibrils detection of nuclei... 

Walsh DM, Lomakin A, Benedek GB, Condron MM, Teplow DB. Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate. J Biol Chem 1997 272 22364-22372. 

Isobe I, Michikawa M, Yanagisawa K. Enhancement of MTT, a tetrazolium salt, exocytosis by amyloid beta-protein and chloroquine in cultured rat astrocytes. Neurosci Lett 1999 266 129-132. 

Abe K, Saito H. Amyloid beta protein inhibits cellular MTT reduction not by suppression of mitochondrial succinate dehydrogenase but by acceleration of MTT formazan exocytosis in cultured rat cortical astrocytes. Neurosci Res 1998 31 295-305. 

Van Nostrand WE, Melchor JP, Ruffini L. Pathologic amyloid beta-protein cell surface fibril assembly on cultured human cerebrovascular smooth muscle cells. J Neurochem 1998 70 216-223. 

Frackowiak J, Mazur Kolecka B, Wisniewski HM, Potempska A, Carroll RT, Emmerling MR, Kim KS. Secretion and accumulation of Alzheimer s beta-protein by cultured vascular smooth muscle cells from old and young dogs. Brain Res 1995 676 225-230. 

Prior R, D DU, Frank R, Prikulis I, Pavlakovic G. Experimental deposition of Alzheimer amyloid beta-protein in canine leptomeningeal vessels. Neuroreport 1995 6 1747-1751. 

Tomiyama T, Shoji A, Kataoka K, Suwa Y, Asano S, Kaneko H, Endo N. Inhibition of amyloid beta protein aggregation neurotoxicity by rifampicin. Its possible function as a hydroxyl radical scavenger. J Biol Chem 1996 271 6839-6844. 

Sheinerman, F. B. Brooks, C. L., Molecular picture of folding of a small alpha/beta protein., Proc. Natl Acad. Sci. USA Feb 1998, 95, 1562-1567. 

Selkoe, D. J. (1996). Amyloid beta-protein and the genetics of Alzheimer s disease. J. Biol. Chem. 271, 18295-8. 

Lomakin, A., Chung, D. S., Benedek, G. B., Kirschner, D. A., and Teplow, D. B. (1996). On the nucleation and growth of amyloid beta-protein fibrils Detection of nuclei and quantitation of rate constants. Proc. Natl. Acad. Sci. USA 93, 1125-1129. 

Arispe, N., Rojas, E., and Pollard, H. B. (1993). Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes Blockade by tromethamine and aluminum. Proc. Natl. Acad. Sci. USA 90, 567-571. 

Flock, D., Colacino, S., Colombo, G., and Di Nola, A. (2006). Misfolding of the amyloid beta-protein A molecular dynamics study. Proteins 62, 183-192. 

Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., Teplow, D. B., and Selkoe, D. J. (1999). Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical... 

Lashuel, H. A., Petre, B. M., Wall, J., Simon, M., Nowak, R. J., Walz, T., and Lansbury, P. T., Jr. (2002). Alpha-synuclein, especially the Parkinson s disease-associated mutants, forms pore-like annular and tubular protofibrils./. Mol. Biol. 322,1089-1102. LeVine, H. (1993). Thioflavine T interaction with synthetic Alzheimer s disease beta-amyloid peptides Detection of amyloid aggregation in solution. Protein Sci. 2, 404—410. Lin, H., Bhatia, R., and Lai, R. (2001). Amyloid beta protein forms ion channels Implications for Alzheimer s disease pathophysiology. FASEB J. 15, 2433-2444. Lorenzo, A., and Yankner, B. A. (1994). Beta-amyloid neurotoxicity requires fibril formation and is inhibited by Congo red. Proc. Natl. Acad. Sci. USA 91, 12243-12247. Luhrs, T., Ritter, C., Adrian, M., Riek-Loher, D., Bohrmann, B., Dobeli, H., Schubert, D., and Riek, R. (2005). 3D structure of Alzheimer s amyl o id-( be la) (1—12) fibrils. Proc. Natl. Acad. Sci. USA 102, 17342-17347. 

Tomiyama, T., Asano, S., Suwa, Y., Morita, T., Kataoka, K., Mori, H., andEndo, N. (1994). Rifampicin prevents the aggregation and neurotoxicity of amyloid beta protein in vitro. Biochem. Biophys. Res. Commun. 204, 76-83. 

Burke, M. J., and Rougvie, M. A. (1972). Cross-beta protein structures. I. Insulin fibrils. 

Castano, E. M., Ghiso, J., Prelli, F., Gorevic, P. D., Migheli, A., and Frangione, B. (1986). In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer s disease beta-protein. Biochan. Biophys. Res. Commun. 141, 782-789. 

Halverson, K., Fraser, P. E., Kirschner, D. A., and Lansbury, P. T., Jr. (1990). Molecular determinants of amyloid deposition in Alzheimer s disease Conformational studies of synthetic beta-protein fragments. Biochemistry 29, 2639-2644. 

Kirschner, D. A., Inouye, H., Duffy, L. K., Sinclair, A., Lind, M., and Selkoe, D.J. (1987). Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro. Proc. Natl. Acad. Sci. USA 84, 6953-6957. 

Fibrous Proteins Amyloids. Prions and Beta Proteins... 

Walsh, D.M., Klyubin, I., Fadeeva, J.V., Cullen, W.K., Anwyl, R., Wolfe, M.S., Rowan, M.J., and Selkoe, D.J., Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo, Nature, 416,535, 2002. 

Lu, D. C. et al. A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor. Nat. Medicine 2000, 6, 397—404. 

Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, et al. 2001. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a foreign body. J Neurochem 78 121-128. 

Yoshikai, S., Sasaki, H., Doh-ura, K., Furuya, H., Sakaki, Y. (1990) Genomic organization of the human amyloid beta-protein precursor gene. Gene, 87, 257-263. 

Tanzi, R.E., Vania, G., Romano, D.M., et al. (1992) Assessment of amyloid beta-protein precursor protein gene mutations in a large set of familial and sporadic Alzheimer disease cases. Am. J. Hum. Genet., 51, 273-282. 

Suzuki, N., Cheung, T.T., Cai, X.-D., et al. (1994) An increased percentage of long amyloid beta protein secreted by fanrUial amyloid beta protein precursor (beta-APP-717) mutants. Science, 264,1336-1340. 

Kang, D.E., Pietrzik, C.U., Baum, L., et al. (2000) Modulation of amyloid beta-protein clearance and Alzheimer s disease susceptibility by the LDL receptor-related protein pathway. J. Clin. Invest., 106, 1159-1166. 

Citron, M., Westaway, D., Xia, W., et al. (1997) Mutant presenilins of Alzheimer s disease increase production of 42-residue amyloid beta-protein in both transfected ceUs and transgenic mice. Nat. Med., 3, 67-72. 

Vitali, A., Piccini, A., Borghi, R., et al. (2004) Soluble amyloid beta-protein in increased in frontotemporal dementia with tau gene mutations. J. Alzheimer Dis., 6, 45-51. 

Luo, H.M., Deng, H., Xiao, F., et al. (2004) Down-regulation amyloid beta-protein 42 production by interfering with transcript of presenUin 1 gene with siRNA. Acta Pharmacol. Sin., 25, 1613-1618. 

Nicoll, J.A.R., Roberts, G.W., Graham, D.l. (1995) ApoUpoprotein E epsUon-4 allele is associated with deposition of amyloid beta-protein foUowing head injury. Nat. Med., 1, 135-137. 

Tokuda, T., Tamaoka, A., Matsuno, S., et al. (2001) Plasma levels of amyloid-beta proteins do not differ between subjects taking statins and those not taking statins. Arm. Neurol., 49, 546-547. 

Mann, D.M., Iwatsubo, T., Pickering-Brown, S.M., Owen, F., Saido, T.C., Perry, R.H. (1997) Preferential deposition of amyloid beta protein (Abeta) in the form of Abeta40 in Alzheimer s disease associated with a gene dosage effect of the apolipoprotein E E4 aUele. Neurosci. Lett., 221, 81-84. 

Morishima-Kawashima, M., Oshima, N., Ogata, H., et al. (2000) Effect of apoUpoprotein E allele epsUon 4 on the initial phase of amyloid beta-protein accumulation in the human brain. Am. J. Pathol, 157, 2093-2099. 

Chauhan A, Chauhan VPS, Brockerhoff H, Wisniewski HM (1991) Action of amyloid beta-protein on protein kinase C activity. Life Sci 49 1555-1562 Chen PL, Chen CF, Chen Y, Xiao J, Sharp ZD, Lee WH (1998) The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesul-fonate treatment. Proc Natl Acad Sd USA 95 5287-5292 Chen CY, Faller DV (1999) Selective inhibition of protein kinase C isoenzymes by Fas ligation.) Biol Chem 274 15320-15328... 

Farris, W., Mansourian, S., Chang, Y., Linsley, L., Eckman, E. A., Frosch, M. P., Eckman, C. B., Tanzi, R. E., Selkoe, D. J., and Guennette, S. (2005). Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proc. Natl. Acad. Sci. USA 100, 4162—4167. 

---