Axon guidance

Negishi M, Oinuma I, Katoh H (2005) Plexins axon guidance and signal transduction. Cell Mol Life Sci 62 1363-1371... 

Neuropilin-1 (NRP1), a molecule that had been previously shown to be implicated in axon guidance as a receptor for members of collapsin/semaphorin family, has been characterized as a which interacts with the heparin-binding VEGF isoforms. 

LRP5 and 6 are not required for Wnt/non-(3-catenin signaling instead a protein called Ryk (derailed in Drosophila) is the best characterized coreceptor for the Fz proteins in non-(3-catenin signaling. Ryk/derailed was first implicated in axon guidance, but could conceivably play a more general role in all forms of Wnt/non-P-catenin signaling controlling cell shape, movement, and polarity. 

Axon Reflex Axonal Guidance Axonal Membrane Azole... 

Ranscht B. Cadherins molecular codes for axon guidance and synapse formation. Int J Dev Neurosci 2000 18[7] 643— 651. 

Gallo G. Axon guidance GTPases help axons reach their targets. Curr Biol 1998 8 R80-82. 

Fig. 5. (a) Schematic of the scaffold design showing the inner and outer scaffolds, (b and c) Inner scaffolds seeded with NSCs. (Scale bars 200 pm and 50 tm, respectively.) The outer section of the scaffold was created by means of a solid-liquid phase separation technique that produced long, axially oriented pores for axonal guidance as well as radial pores to allow fluid transport and inhibit the ingrowth of scar tissue (d scale bar, 100 pm), (e) Schematic of surgical insertion of the implant into the spinal cord. [Reproduced with permission from Teng et al. (2002).]... 

To perform its unique functional role each neuron must regulate a host of intracellular activities, that occur in axons and dendrites distant from the cell nucleus. For example, axonal guidance during development, or remodeling of dendritic spines in response to local input, each involves many different complex control systems that are highly localized and largely autonomous. [ 1 ]. 

Dickson, B. J. Molecular mechanisms of axon guidance. Science 298 1959-1964,2002. 

Tessier-Lavigne, M. and Goodman, C. S. The molecular biology of axon guidance. Science 274 1123-1133,1996. 

Somatic motor and sensory neurons that give rise to PNS axons maintain large fractions of their total protoplasmic bulk within the CNS. Many of the extracellular matrix components and axonal guidance molecules involved in... 

PDGFR platelet-derived growth factor receptor RAGS repulsive axon guidance signal... 

Serafini, T., Colamarino, S.A., Leonardo, E.D., Wang, H., Bedding-ton, R., Skarnes, W.C., and Tessier-Lavigne, M. (1996) Netrin-1 is required for commissural axon guidance In the developing vertebrate nervous system. Cell 87 1001-1014. 

Lee, H., Engel, U., Rusch, J., Scherrer, S., Sheard, K., and Van Vactor, D. (2004). The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance. Neuron 42, 913-926. 

Pulsinelli WA, Brierly JB, Plum F (1982) Temporal profile of neuronal damage in a model of transient brain ischemia. Ann Neurol 11 491-498 Quinn CC, Gray GE, Hockfield S (1999) A family of proteins implicated in axon guidance and outgrowth. J Neurobiol 41 158-164... 

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