Atherosclerosis Risk in Communities study

Carnethon MR, Anthony MS, Cascio WE, Folsom AR, Rautaharju PM, Liao D, Evans GW, Heiss G. A prospective evaluation of the risk of QT prolongation with hormone replacement therapy the atherosclerosis risk in communities study. Ann Epidemiol 2003 13 530-6. 

Gress, T. W., Nieto, F. J., Shahar, E., et al. 2000. Hypertension and antihypertensive therapy as risk factors for type 2 diabetes mellitus. Atherosclerosis Risk in Communities Study. N Engl J Med 342 905-912. 

Liao D, Cooper L, Cai J, Toole JF, Bryan NR, Hutchinson RG, Tyroler HA (1996) Presence and severity of cerebral white matter lesions and hypertension, its treatment, and its control. The ARIC study. Atherosclerosis risk in communities study. Stroke 27 2262-2270... 

This study confirmed the findings of another project, the Atherosclerosis Risk in Communities Study, which found that retinal blood vessel narrowing predicted hypertension within three years. Doctors point out that by knowing the risk of future blood pressure problems, one can immediately take lifestyle modification steps to avoid them. 

Das UN. Can perinatal supplementation of long-chain polyunsaturated fatty acids prevent atopy, bronchial asthma and other in-flanunatory conditions Med. Sci. Monit. 2006 12 RA99-RA111. Beydotm MA, Kaufman JS, Satia JA, Rosamond W, Folsom AR. Plasma n-3 fatty acids and the risk of cognitive decline in older adults the Atherosclerosis Risk in Communities Study. Ant J. CUn. Nutr. 2007 87 1103-1111. 

Offenbacher, S. et al.. Association of coronary heart disease with interleukin 1 gene variants in the Atherosclerosis Risk in Communities Study, in The American College of Cardiology Annual Scientific Session, Abstract No. 1028-166, 2004. 

Fuchs FD, Ch bless LE, Whelton PK, Nieto FJ, Heiss G. Alcohol consumption andtiie incidence of hypertension. The Atherosclerosis Risk in Communities Study. Hypertension (2001)37, 1242-50. 

Muntner, P., He, J., Astor, B.C., Folsom, A.R., and Coresh, J., 2005. Traditional and nontraditional risk factors predict coronary heart disease in chronic kidney disease results from the atherosclerosis risk in communities study. Journal of the American Society of Nephrology. 16 529-538. 

Vitelli LL, Shahar E, Heiss G, et al. Glycosylated hemoglobin level and carotid intimal-medial thickening in nondiabetic individuals. The Atherosclerosis Risk in Communities Study. Diabetes Care 1997 20 1454-1458. 

Diez-Roux AV, Nieto FJ, Tyroler HA, Cmm LD, Szklo M. Social inequalities and atherosclerosis. The atherosclerosis risk in communities study. Am J Epidemiol 1995 141 960-972. 

Hwang SJ, Ballantyne CM, Sharrett AR, Smith LC, Davis CE, Gotto AM Jr, Boerwinkle E (1997) Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases the Atherosclerosis Risk In Communities (ARIC) study. Circulation 96 4219-4225... 

B25. Brown, S. A., Morrisett, J. D., Boerwinkle, E., Hutchinson, R., and Patsch, W., The relationship of Lipoprotein(a) concentrations an apolipoprotein(a) phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler. Thromb. 13, 1558-1566 (1993). 

Sharrett AR, Ballantyne CM, Coady SA, et al. Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein (a), apolipoproteins A-I and B, and HDL density subfractions the Atherosclerosis Risk in Communities (ARIC) study. Circulation 2001 104 1108-13. 

Ma, J., Folsom, A. R., Shahar, E., and Eckfeldt, J. H. (1995). Plasma fatty acid composition as an indicator of habitual dietary fat intake in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study Investigators. Am. J. Clin. Nutr. 62,564-571. 

Chambless LE, Folsom AR, Davis Y et al. Risk factors progression of common carotid atherosclerosis the Atherosclerotic Risk in Communities Study, 1987-1998. Am J Epidemiol 2002 155 38-47. 

Ballantyne CM, Hoogeveen RC, Bang H, Coresh J, Folsom AR, Chambless LE, Myerson M, Wu KK, Sharrett AR, Boerwinkle E (2005) Lipoprotein-associated phosphohpase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study. Arch Intern Med 165 2479-2484. 

Brown SA, Hutchinson R, Morrisett J, Boerwinkle E, Davis CE, Gotto AM, Jr., Patsch W. Plasma lipid, hpoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study. Arterioscler Thromb 1993 13 1139-58. 

The Atherosclerosis Risk in Communities (ARIC) Study design and objectives. The ARIC investigators. Am J Epidemiol 1989 129 687-702. 

Dekker JM, Crow RS, Folsom AR, et al. Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes the ARIC study. Atherosclerosis Risk In Communities. Circulation2000 102(11) 113—20. 

Duncan, B.B., Schmidt, M.I., Chambless, L.E., Folsom, A.R., Carpenter, M., and Heiss, G. 2000. Fibrinogen, other putative markers of inflammation, and weight gain in middle-aged adults—the ARIC study. Atherosclerosis risk in communities. Obes. Res. 8, 279-286. 

The ARIC Investigators, The Atherosclerosis Risk in Communities (ARIC) Study design and objectives. The ARIC investigators. Am. J. Epidemiol., 129, 687, 1989. Francis, S.E. et al., lnterleukin-1 receptor antagonist gene polymorphism and coronary artery disease. Circulation, 99, 861, 1999. 

The Atherosclerosis Risk in Communities (ARIC) study involving 8334 subjects who were free from hypertension at baseline and were assessed after 6 years, found that higher levels of consumption of alcoholic beverages (210 g or more of alcohol per week approximately 3 drinks or more per day) were associated with a higher risk of hypertension. Low to moderate consumption of alcohol (up to 3 drinks/day) was associated with an increase in blood pressure in black, but not in white men. A study in Japanese men found that the effect of alcohol intake on the risk of developing hypertension was dose-dependent, starting at low-to-moderate levels of alcohol (less than 23 g/day). ... 

Wang L, Folsom AR, Zheng ZJ, Pankow JS, Eckfeldt JH. Plasma fatty acid composition and incidence of diabetes in middle-aged adults the Atherosclerosis Risk in Communities (ARIC) study. Am J Clin Nutr. 2003, 78 91-98. 

Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC (2007) CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk the Atherosclerosis Risk in Communities (ARIC) study. Pharmacogenet Genomies 17 349—358... 

Folsom, A., Nieto, F., McGovern, P., Tsai, M., Malinow, M., Eckfeldt, J., Hess, D., and Davis, C., 1998. Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins the Atherosclerosis Risk in Communities (ARIC) study. Circulation. 98 204-210. 

However, in a prospective study, atherosclerosis risk in communities (ARIC), there was doubt about a relation between CHD and Hey and no association between CHD and C677T mutation of methylenetetrahydro-folate reductase gene or three mutations of cystathionine P-synthase gene. However, it was possible that vitamin Bg offered an independent protection (143), and recently a review concluded that there is insufficient evidence to regard Hey levels as a causative factor in atherosclerosis (144). 

Golden SH, Maguire A, Ding J, et al. Endogenous postmencqiausal hormcmes and carotid atherosclerosis a case-control study of the atherosclerosis risk in communities cohort. Am J Epidemiol 2002 155 437-445. 

In a community-based study in Taiwan, hypertension was found to strongly influence carotid atherosclerosis (10). In addition, the fasting insulin and insulin/glucose ratio are independent risk factors for the accelerated development of CAD (11,12). However, it should be noted that the administration of exogenous insulin or the sulphonylureas, which are insulin secretagogues, did not increase cardiovascular disease (C VD) especially exogenous insulin. Thus, insulin may not be the primary culprit implicated in the increased mortality from CHD (13). 

Feigin VL, Wiebers DO, Nikitin YP et al. (1998). Risk factors for ischemic stroke in a Russian community a population-based case-control study. Stroke 29 34-39 Fine-Edelstein JS, Wolf PA, O Leary et al. (1994). Precursors of extracranial carotid atherosclerosis in the Framingham Study. Neurology 44 1046-1050 Gabriel SR, Carmona L, Roque M et al. (2005). Hormone replacement therapy for preventing cardiovascular disease in post-menopausal women. Cochrane Database Systems Review 2 CD002229... 

Frontini, MG, Srinivasan, SR, Elkasabany, A and Berenson, GS (2001) Distribution and cardiovascular risk correlates of serum triglycerides in young adults from a biracial community the Boga lusa Heart Study. Atherosclerosis, 155, 201-209. 

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