Atherosclerosis prevention

Wedworth, S.M., and Lynch, S., 1995, Dietary flavonoids in atherosclerosis prevention, Pharmacother. 29 627-628. 

Downs JR, Clearfield M, Weis S, Whitney E, Shapiro DR. Primary prevention of acnte coronary events with lo-vastatin in men and women with average cholesterol levels resnlts of AECAPS/TexCAPS. Air Eorce/Texas Coronary Atherosclerosis Prevention Study. JAMA 1998 279 1615-22. 

In the general population for primary prevention of CHD The West of Scotland Coronary Prevention Study (WOSCOPS) (9), Air Force/Texas coronary atherosclerosis Prevention study (AFCAPS/TexCAPS) (10), and the completed but unpublished MEGA study in Japan (A. Nakamura, presented to AHA Scientific Sessions, November 2005). 

Cambridge Heart Antioxidant Study DATATOR Deprenyl and Tocopherol Antioxidative Therapy of Rarkinsonism FMC, Finnish Mobile Clinic Health Examination Survey GISSI, Gruppo Italiano Studio Soprawivenza Infarto HOPE, Heart Outcome Prevention Evaluation HPFS, Health Professional Follow-up Study NHS, Nurses Health Study PPR Primary Prevention Project SPACE, Secondary Prevention with Antioxidants of Cardiovascular disease in End-stage renal disease VEAPS, Vitamin E Atherosclerosis Prevention Study VECAT Vitamin E Cataract Age-related maculopathy Trial. 

Hodis HN, Mack WJ, LaBree L, et al. Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis. The Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation 2002 106 1453-1459. 

Sirtori CR Pharmacology of sulfomucopolysaccharides in atherosclerosis prevention and treatment In Riod G, et al, Eds Selectivity and Ritic-Bm t Assessmesft of Hyperlipidemia Drugs. Raven Press, New Yoik,pp 189-94,1982... 

In 1997, garlic was the most widely used natural supplement in US households. Garlic was shown to be used more than twice as much as any other natural supplement (5). Garlic is promoted to lower cholesterol and blood pressure, delay the progression of atherosclerosis, prevent heart disease, improve circulation, prevent cancer, and is used topically for tinea infections (3,4). 

Gotto AM, Jr., Whitney E, Stein EA, Shapiro DR, Clearfield M, Weis S, et al. Relation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). Circulation 2000 101 ... 

AECAPS/TexCAPS = Air ForceAexas Coronary Atherosclerosis Prevention Study (Downs et ah, 1998) Helsinki = The Helsinki Heart Study (Frick et al., 1 987) LRC-CPPT = The Lipid Research Clinics Coronary Primary Prevention Trial (insull et al., 1984) Oslo = The Oslo Study (Hjermann et ah, 1988) WOSCOPS = The West of Scotland Coronary Prevention Study (Shepherd et al., 1995) ALLHAT = Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial approximately 13-15% of patients had a history of coronary heart disease (CHD) events are CHD events only WHI = Women s Health initiative RRR = relative risk reduction ARR = absolute risk reduction NNT = number needed to treat NA = not available CEE = conjugated equine estrogen MPA = medroxyprogesterone acetate CARDS = Collaborative Atorvastatin Diabetes Study (presented at the 2004 American Diabetes Association meeting). 

Hodis, H.N., Mack, W.J., LaBree, L., Mahrer, ER., Sevanian, A., Liu, C.R., Liu, C.H., Hwang, J., Selzer, R.H., and Azen, S.R, Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis the Vitamin E Atherosclerosis Prevention Study (VEAPS), Circulation 106 (12), 1453-1459, 2002. 

T. H. Rissanen, T. P. Tuomainen et al. Antioxidant Supplementation in Atherosclerosis Prevention. 2003. Six-year effect of combined vitamin C and E supplementation on atherosclerotic progression The Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study. 1 - 947-953. 

MUNTEANU, A. ZINGG, J. M. 2007. Cellular, molecular and clinical aspects of vitamin E on atherosclerosis prevention. Mol Aspects Med, 28, 538-590. 

SALONEN, J. T NYYSSONEN, K SALONEN, R LAKKA, H. M KAIKKONEN, J PORKKALA-SARATAHO, E VOUTILAINEN, S LAKKA, T. A., RISSANEN, T LESKINEN, L TUOMAINEN, T. P., VALKONEN, V. R, RISTONMAA, U. POULSEN, H. E. 2000. Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study A randomized trial of the effect of vitamins E and C on 3-year progression of carotid atherosclerosis. J Intern Med, 248, 377-86. 

Ridker PM, Rifai N, Clearfield M, et al. Air Force/Texas Coronary Atherosclerosis Prevention Study Investigators. Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. N Engl J Med 2001 344 1959-1965. 

Yokote K, Bujo H, Hanaoka H, Shinomiya M, Mikami K, Miyashita Y, Nishikawa T, Kodama T, Tada N, Saito Y. Multicenter collaborative randomized parallel group comparative study of pitava-statin and atorvastatin in Japanese hypercholesterolemic patients collaborative study on hypercholesterolemia drug intervention and their benefits for atherosclerosis prevention (CHIBA study). Atherosclerosis 2008 201(2) 345-52. 

The research areas covered by the Meeting are very wide, having to do with the liver and biliary pathophysiology, nutrition, gallstone disease and atherosclerosis prevention. Scientists from the major clinical and basic disciplines provided an update overview of the complex mechanisms regulating the biosynthesis and catabolism of cholesterol and the formation and metabolism of bile acids. 

Antioxidants of Cardiovascular Disease in Endstage Renal Disease (SPACE) study and the Antioxidant Supplementation in Atherosclerosis Prevention Study (ASAP). 

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