Assessments Guidance

NICE] National Institute for Clinical Effectiveness (2001). Guidanee on the Use of Donepezil, Rivastigmine and Galantamine far the Treatment of Alzheimer s Disease. Technology Assessment Guidance No. 19. London ... 

EPA (1989) Risk Assessment Guidance for Superfund. Volume I. Human Health Evaluation Manual. EPA/540/1-89/002. 

US EPA, Assigning Values to Non-detected/Non-quantified Pesticide Residues in Human Health Food Exposure Assessments, Guidance Document Office of Pesticide Programs, US Environmental Protection Agency, Washington, DC (March 23,2000). Also available on the World Wide Web http //www.epa.gov/pesticides/trac/science/trac3b012.pdf. 

ATSDR. 1992. Public health assessment guidance manual. US Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry. Atlanta, GA. 

SADA provides a full human health risk assessment module and associated databases. The risk models follow the USEPA s Risk Assessment Guidance for Superfund (RAGS) and can be customized to fit site-specific exposure conditions. It calculates risks based on the following exposure pathways ingestion, inhalation, dermal contact, food consumption, and also a combined exposure. 

United States Environmental Protection Agency (USEPA) (1989) Risk Assessment Guidance for Superfund. Volume 1. EPA/540/1-89/002. Office of Emergency and Remedial Response. U.S. Environmental Protection Agency, Washington, DC... 

US-EPA has formed the Risk Assessment Forum, a standing committee of senior US-EPA scientists, to promote US-EPA consensus on difficult and controversial risk assessment issues and to ensure that this consensus is incorporated into appropriate US-EPA risk assessment guidance. To fulhil this purpose, the Forum assembles US-EPA risk assessment experts in a formal process to study and report on issues from a US-EPA scientific perspective. Major Fomm guidance documents are developed in accordance with the US-EPA s regulatory and policy development process and become US-EPA pohcy upon approval by the Administrator or the Deputy Administrator. The Risk Assessment Forum products include risk assessment guidelines, technical panel reports on special risk assessment issues, and peer consultation and peer review workshops addressing controversial risk assessment topics. 

USEPA] US Environmental Protection Agency. 1999. Risk assessment guidance for superfund volume 3, part A, process for conducting probabilistic risk assessment. Washington (DC) EPA 000-0-99-000. Office of Emergency and Remedial Response. 

U S Environmental Protection Agency. Risk Assessment Guidance for Superfund (RAGS), Vol. I Human Health Evaluation Manual (Part E, Supplemental Guidancefor Dermal Risk Assessment) Interim, 2004 http //www.epa.gov/oswer/ riskassessment/ragse/index.htm (last accessed 12 July 2010). 

USEPA (2001) Risk assessment guidance for Superfund. Vol. Ill, Part A. Process for conducting probabilistic risk assessment (RAGS 3A). Washington, DC, United States Environmental Protection Agency (EPA 540-R-02-002 OSWER 9285.7-45 PB2002 963302 http //www.epa.gov/oswer/riskassessment/rags3adt/index.htm). 

ATSDR (1992) Public Health Assessment Guidance Manual. Chelsea, MI Lewis Publishers. 

No 19 Testing and Assessment Guidance Document on the Recognition, Assessment and Use of Clinical Signs as Humane Endpoints (2000). 

Source Risk Assessment Guidance for Superfund [14]. Note Both exposure and RfD are in units of mg/kg-day. 

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