Macular degeneration, antioxidants

Snodderly, D.M., Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am. J. Clin. Nutr, 62, 1448S, 1995. [Pg.143]

In the Unites States, the daily intake of 3-carotene is around 2 mg/day Several epidemiological studies have reported that consumption of carotenoid-rich foods is associated with reduced risks of certain chronic diseases such as cancers, cardiovascular disease, and age-related macular degeneration. These preventive effects of carotenoids may be related to their major function as vitamin A precursors and/or their actions as antioxidants, modulators of the immune response, and inducers of gap-junction communications. Not all carotenoids exert similar protective effects against specific diseases. By reason of the potential use of carotenoids as natural food colorants and/or for their health-promoting effects, research has focused on better understanding how they are absorbed by and metabolized in the human body. [Pg.161]

Astaxanthin is a powerful bioactive antioxidant and has demonstrated efficacy in animal and human models of macular degeneration, a cause of blindness in a large population. It is also helpful in treating Alzheimer s and Parkinson s diseases and is known to offer protection against cancer. [Pg.407]

Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, Tsipursky M, and Nyland J (2004), Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration The Veterans LAST study (lutein antioxidant supplementation trial), Optometry 75 216-30. [Pg.109]

EDCC Study Group (1993). Antioxidant status and neovascular age-related macular degeneration. Arch. Ophthalmol. Ill 104—109. [Pg.277]

Snellen, E. L., A. L. Verbeek et al. (2002). Neovascular age-related macular degeneration and its relationship to antioxidant intake. Acta Ophthalmol. Scand. 80(4) 368-371. [Pg.281]

Mares-Perlman, J.A., Bracy, W.E., Klein, R. et al. 1995. Serum antioxidants and age-related macular degeneration in a population based control study. Arch. Opthalmol. 113 1518-1523. [Pg.306]

Chong, EW, Wong, TY, Kreis, AJ, Simpson, JA, and Guymer, RH, 2007. Dietary antioxidants and primary prevention of age related macular degeneration Systematic review and meta-analysis. BMJ 335, 755. [Pg.341]

Evans, JR, 2006. Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration. Cochrane Database Syst Rev 19(2) CD000254. [Pg.343]

Tan, JS, Wang, JJ, Flood, V, Rochtchina, E, Smith, W, and Mitchell, P, 2008. Dietary antioxidants and the long-term incidence of age-related macular degeneration The Blue Mountains Eye Study. Ophthalmology 115, 334-341. [Pg.352]

Several studies have linked lutein to a lower risk for eye, skin and other health disorders, probably through its antioxidant activity. Lutein is apparently metabolized to zeaxanthin, an isomer, and several other compounds which protect the macula from ultraviolet radiation. The suggestion is that lutein may play a positive role in reducing macular degeneration. Other reports have linked lutein to a reduction of risk of cancer.13 Regardless, lutein is currently being promoted as an important dietary supplement. [Pg.182]

Clinical trials have also been conducted to study the effect of the antioxidants on the progression of age-related macular degeneration (AMD) and vision loss. The Age-Related Eye Disease Study Research Group recommends supplements of zinc and antioxidants for adults at risk for developing AMD. However, the group... [Pg.781]

Bilberry (Vbccinium myrtillus) Uses Prevent/treat visual problems such as cataract, retinopathy, myopia, glaucoma, macular degeneration treat vascular problems such as hemorrhoids, varicose veins Actions Contains anthocyanidin that 1 vascular permeability, inhibit pit aggregation thrombus formation, T antioxidant effects on LDLs liver, T regeneration of rhodopsin... [Pg.324]

It is also well documented that an antioxidant-rich diet protects against age-related macular degeneration (AMD), the leading cause of vision loss among the elderly. Development of AMD in the retinal pigment epithelium (RPE) is associated with oxidative stress. King and co-workers [2005] reported that resveratrol treatment (100 pmol/L) inhibited basal and H202-induced... [Pg.318]

Bell pepper is rich in antioxidant vitamin C. It helps to fight off colds, asthma, bronchitis, respiratory infections, cataracts, macular degeneration, angina, atherosclerosis, and cancer. [Pg.211]

Hogg, R. and Chakravarthy U., Age related macular degeneration and micronutrient antioxidants, Curr. Eye... [Pg.664]

Moriarty-Craige, S. Adkison, J. Lyim, M. Gensler, G. Bressler, S. Jones, D. Stemberger, P. 2005. Antioxidant supplements prevent oxidation of cysteine/ cystine redox inpatients with age-related macular degeneration. Am. J. Ophthalmol. 140 1020-1026. [Pg.383]

Jampol LM. Antioxidants, zinc, and age-related macular degeneration results and recommendations [comment]. Arch Ophthalmol 2001 119 1533. [Pg.641]

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