Anti-microbial activity

SHIMAMURA T (1991) The anti-microbial activity of tea , in Proc of Intern Symp on Tea Sci, 26-29 August, 1991, Shizuoka, Japan, 27-31. 

Epidemiological studies and intervention trials with food and beverages rich in flavonoids are not conclusive although flavonoids were recognized to display numerous antioxidant, anti-inflammatory, anti-tumoral, and anti-microbial activities. The antioxidant capacity of flavonoids has been largely reported in numerous in vitro and ex vivo systems. Numerous reviews "" have been published on the antioxidant properties of flavonoids. Degenerative diseases are largely associated with oxidative mechanisms that may be counteracted by flavonoids. 

Hibbs, J.B. (1991). Synthesis of nitric oxide from L-atginine a recently discovered pathway induced by cytokines with antitumour and anti-microbial activity. Res. Immunol. 142, 565-569. 

Lymphocyte proliferation Anti-microbial activity Cytokine production... 

Serum Ig levels Cellular immunity Anti-microbial activity Humoral immunity Apoptosis Cell signaling... 

The interaction between melittin (a 26 a.a. peptide that exhibits potent anti-microbial activity)90 92 and lipopolysaccharides (the major constituent of the outer membrane of the Gram-negative bacteria) has been studied by NMR. It was demonstrated that the C-terminus of melittin adopts a helical structure in the complex with LPS, while the Y-terminus appears in an extended conformation. STD experiments permitted to identify those residues of melittin in close proximity with LPS, which appeared to be located at the C-terminus and thus, engaged in the formation of helical structure. 

The structures and sources of many allelochemicals with anti-microbial activity have been documented (Dixon, 2001 Grayer and Harbome, 1994 Harbome, 1999). In this chapter, evidence for anti-microbial functions of allelochemicals from weed Ageratum conyzoides L. and food crop Oryza sativa L. has been reviewed. Effects of these allelochemicals on related pathogen management in the A. conyzoides intercropped citrus orchard and the paddy ecosystem were discussed. 

Bacteriocins are compounds with potential anti-microbial activity synthesized by many bacterial species, including lactic acid bacteria (Cotter et al., 2005 Gotteland et al., 2006). As the ability of bacteriocins to... 

Nadaraj V, Selvi ST, Mohan S (2009) Microwave-induced synthesis and anti-microbial activities of 7, 10, 11, 12-tetrahydrobenzo[c]acridin-8(9H)-one derivatives. Eur J Med Chem 44 976-980... 

BL-P1654. A penicillin with broad spectrum anti-microbial activity [86] (See Table 7.1), it is more active than carbenicillin against strains of Ps. aeruginosa, the majority of strains being inhibited by 8 /rg/ml [75]. The sulphoamino penicillins. A number of these compounds have been investigated for their anti-pseudomonas activity and for their j3 -lactamase resistance [87]. BL-P1462 (Table 7.1) [88] is one such compound. 

Pemak J, Goc I, Mirska I. Anti-microbial activities of protic ionic liquids with lactate anion. Green Chem. 2004. 7, 323-329. 

Cieniecka-Roslonkiewicz Anna, Pemak Juhusz, Kubis-Feder Joanna, et al. Synthesis, anti-microbial activities and anti-electrostatic properties of phosphonium-based ionic hquids. Green Chem. 2005. 7, 855-862. 

From a marine-derived strain of the fungus Emericella variecolor, varitriol 26, varioxirane 27, dihydroterrein 28, and varixanthone 29 were found. In the NCI s 60-cell panel, 26 displayed potency toward selected renal, CNS, and breast cancer cell lines. 29 showed anti-microbial activity. Studies toward the total synthesis and absolute configurational determination of (+)-26 were achieved. ... 

Bioactivity-guided fractionation of organic extracts of Cladosporium herbarum, isolated from the marine sponge Callyspongia aerizusa, yielded two new macrolide metabolites, pandangolide 3 172 and 4 173, and a anti-microbial active (against Bacillus subtilis and Staphylococcus aureus) new fliran carboxylic acids, acetyl Sumiki s acid 174/ ... 

Two new indole nucleosides kahakamides A 256 and B 257 were isolated from the actinomycete Nocardiopsis dassonvillei which is obtained from a shallow water sediment sample collected from the island of Kauai, Hawaii. Compound 256 exhibited anti-microbial activity toward the Gram positive bacterium Bacillus subtilis. 

Three novel antibiotics, chandrananimycin A 260, B 261, and C 262, were isolated from the culture broth of a marine Actinomadura sp. isolate M048. Their anti-microbial activities ranged from moderate to strong, and they were also active against some human tumor cell lines. 

A new dibenzodiazepine alkaloid, diazepinomicin 265, was isolated from the culture of a marine actinomycete of the genus Micromonospora Compound 265 showed modest anti-microbial activity against selected Gram-positive bacteria with MICs of about 32 pg mL". The method of expression the biosynthetic pathway genes in transformed host cells, and the novel polynucleotide sequences and their encoded proteins involved in the biosynthesis of 265 were discussed. Derivatives of 268 were prepared. ... 

Locher CP, Burch MT, Mower HF, et al. Anti-microbial activity and anti-complement activity of extracts obtained from selected Hawaiian medicinal plants. J Ethnopharmacol 1995 49 23-32. 

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