Callyspongia aerizusa

Bioactivity-guided fractionation of organic extracts of Cladosporium herbarum, isolated from the marine sponge Callyspongia aerizusa, yielded two new macrolide metabolites, pandangolide 3 172 and 4 173, and a anti-microbial active (against Bacillus subtilis and Staphylococcus aureus) new fliran carboxylic acids, acetyl Sumiki s acid 174/ ... 

Pandagolides 1 and 2 are produced by fungi associated with an unidentified sponge harvested in Indonesia (Smith et al, 2000) (see above). Very similar molecules, pandagolides 3 and 4, were isolated from cultures of the fungus Cladosporium herbarum associated with the sponge Callyspongia aerizusa (Jadulco et al, 2001). 

Ibrahim, S.R.M., Edrada-Ebel, R.U., Mohamed, G.A., Youssef, D.T.A., Wray, V., and Proksch, P. (2008b) Callyaerin G, a new cytotoxic cyclic peptide from the marine sponge Callyspongia aerizusa. ARKIVOC, 164-171. 

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