4-aminophenyl

A series of water-soluble fiber-reactive xanthene dyes has been prepared from the reaction of ben2oxanthenedicatboxylic acid anhydride disulfonic acid with, for example, 3-aminophenyl-P-hydtoxyethyl sulfone to yield dyes, with high brilliance and good fastness properties for dyeing of or printing on leather, wool, sHk, or ceUulosic fibers (53). 

A solution of 5.0 g of a-ethyl-(3-(aminophenyl)propionic acid in 100 ml of water containing 5 ml of concentrated hydrochloric acid was added over a period of h hour to a stirred solution of 3.2 ml of Iodine monochioride in 25 ml of water and 25 ml of concentrated hydrochloric acid heated to 60°C. After addition was complete, the heating was continued for h hour longer at 60° to 70°C. A black oil separated which gradually solidified. The mixture was then cooled and sodium bisulfite was added to decolorize. Recrystallization of the product from methanol gave about 8 g of a-ethyl-(3-(2,4,6-triiodo-3-aminophenyl-pro-pionic acid, MP 147° to 150°C. The product could be further purified by precipitation of its morpholine salt from ether solution and regeneration of the free amino acid by treatment of a methanol solution of the morpholine salt with sulfur dioxide. The pure amino acid had the MP 155° to 156.5°C (corr). 

Diethylboryl)pyridines and (3-Aminophenyl)boronic Acid Derivatives... 

A structurally related tetrameric macroheterocycle is compound 13 that is prepared in a one-pot synthesis (yield 64%) from salicylaldehyde and (3-aminophenyl)boronic acid in methanol (Fig. 4). Due to its insolubility it has been characterized only by mass spectrometry. If a substitutent is introduced at the imine function (R = Me, Ph), trimeric structures (14 and 15) are... 

Fig. 4. Tetrameric 13 and trimeric 14, 15 macrocyclic structures obtained from (3-aminophenyl)boronic acid derivatives...

Huot et al. [38] used affinity chromatography to identify and partially purify an amiloride-binding protein with characteristics of the renal brush border Na /H exchanger. The high-affinity amiloride analog A35 (5-A-(3-aminophenyl)amiloride) was coupled to Sepharose CL-4B through a triglycine spacer. Rabbit renal brush border membranes were solubilized with 0.6% Triton X-100, incubated with the... 

The irradiation of 3-( -aminophenyl)-l,2,4-oxadiazoles 65 allowed the process to be extended to the formation of an internal N-N bond (Scheme 4), leading either to the indazoles 68 directly from photolytic species 66, or to the formation of benzimidazoles 69, which were formed from the carbodiimide 67, the rearrangement product of photolytic species 66 <1996JOC8397>. 

Aminophenyl)aminomethylenemalonates (165) and 1,3-bis(amino-methylenemalonates (166) were prepared when m-phenylenediamines... 

The thermal ring closure of diethyl /V-(3-aminophenyl)aminomethylene-malonate (757 R = NH2, R1 = H) and its 4-fluoro derivative (757, R = NH2, R1 = F) in boiling diphenyl ether in the presence of acetic anhydride gave the corresponding ethyl 7-acetamido-4-hydroxyquinoline-... 

Diethyl )V-(3-aminophenyl)aminomethylenemalonate (165, R = H) was diazotized, and the diazonium salt (1582) was then reacted with 2-amino-naphthalene (1583) at 0-10°C (80MI2). 

N-(4-Fluoro-3-aminophenyl)aminomethylenemalonate (1586) was reacted with dimethoxytetrahydrofuran in boiling glacial acetic acid for 3-4 min to give /V-[4-fluoro-3-(l-pyrrolyl)phenyl]aminomethylenema-lonate (1587) in 87% yield (86FRP2574404). 

Alpha ethyl- 8-(2,4,6-triiodo-3-aminophenyl)-propionic acid I-l GB836884 Leo 13... 

Stability for use in optical interconnects. In the near future, optoelectronic integrated circuits and optoelectronic multichip modules will be produced. Materials with high thermal stability will thus become very important in providing compatibility with conventional 1C fabrication processes and in ensuring device reliability. Polyimides have excellent thermal stability so they are often used as electronic materials. Furuya et al. introduced polyimide as an optical interconnect material for the first time. Reuter et al. have applied polyimides to optical interconnects and have evaluated the fluorinated polyimides prepared from 6FDA and three diamines, ODA (3), 2,2-bis(3-aminophenyl) hexafluoropropane (3,3 -6F) (4), and 4,4 -6F (2), as optical waveguide materials. 

Kraus et al.75 78) in Israel fabricated new aromatic phosphoric amide-carboxamide copolymers, which gave membranes high thermal stability, flame resistance, and salt rejection. Thus a copolymer was prepared from N,N -bis(3-aminophenyl)-N"-phenylphosphoric triamide 25, m-phenylenediamine and isophthaloyl chloride in... 

Buffer catalysis of the hydrolysis of phenyl (311 R = Ph) and methyl (311 R = Me) benzenesulfinates to give the sulfinic acid (312) and alcohol ROH is strongly accelerated by both carboxylate and amine components of the buffer which give Bronsted /i values of approximately unity on separate lines. The carboxylates are about 44 tunes more effective than amines of similar basicity. A concerted. S n2 mechanism with a hypervalent intermediate (313) is proposed for the nucleophilic reaction of these esters.286 The reaction of the thiosulfinate esters (314) with sulfenyl chlorides RSCI and sulfenate esters (315) to give sulfinyl chlorides and disulfides and sulfinate esters and disulfides, respectively, has been studied.287 Hydrolysis of 2-(3-aminophenyl)sulfonyl-ethanol hydrogensulfate gives under different conditions various products such as the ether (316) and the sulfone (317).288... 

The hydrolysis of phosphates is discussed in reviews of nucleophile10 and secondary6 isotope effects. The kinetics and mechanism of the acid hydrolysis of 3-aminophenyl phosphate were studied in 0.1-0.6 m HC1 at 90 °C.55... 

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