Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Alcohol reaction

Chloroacetate esters are usually made by removing water from a mixture of chloroacetic acid and the corresponding alcohol. Reaction of alcohol with chloroacetyl chloride is an anhydrous process which Hberates HCl. Chloroacetic acid will react with olefins in the presence of a catalyst to yield chloroacetate esters. Dichloroacetic and trichloroacetic acid esters are also known. These esters are usehil in synthesis. They are more reactive than the parent acids. Ethyl chloroacetate can be converted to sodium fluoroacetate by reaction with potassium fluoride (see Fluorine compounds, organic). Both methyl and ethyl chloroacetate are used as agricultural and pharmaceutical intermediates, specialty solvents, flavors, and fragrances. Methyl chloroacetate and P ionone undergo a Dar2ens reaction to form an intermediate in the synthesis of Vitamin A. Reaction of methyl chloroacetate with ammonia produces chloroacetamide [79-07-2] C2H ClNO (53). [Pg.90]

Many of these reactions are reversible, and for the stronger nucleophiles they usually proceed the fastest. Typical examples are the addition of ammonia, amines, phosphines, and bisulfite. Alkaline conditions permit the addition of mercaptans, sulfides, ketones, nitroalkanes, and alcohols to acrylamide. Good examples of alcohol reactions are those involving polymeric alcohols such as poly(vinyl alcohol), cellulose, and starch. The alkaline conditions employed with these reactions result in partial hydrolysis of the amide, yielding mixed carbamojdethyl and carboxyethyl products. [Pg.133]

The primary and secondary alcohol functionahties have different reactivities, as exemplified by the slower reaction rate for secondary hydroxyls in the formation of esters from acids and alcohols (8). 1,2-Propylene glycol undergoes most of the typical alcohol reactions, such as reaction with a free acid, acyl hahde, or acid anhydride to form an ester reaction with alkaU metal hydroxide to form metal salts and reaction with aldehydes or ketones to form acetals and ketals (9,10). The most important commercial appHcation of propylene glycol is in the manufacture of polyesters by reaction with a dibasic or polybasic acid. [Pg.366]

Commercial alkylphenol ethoxylates are almost always produced by base-cataly2ed ethoxylation of alkylphenols. Because phenols are more strongly acidic than alcohols, reaction with ethylene oxide to form the monoadduct is faster. The product, therefore, does not contain unreacted phenol. Thus, the distribution of individual ethoxylates in the commercial mixture is narrower, and alkylphenol ethoxylates are more soluble in water. [Pg.248]

Reactions with OC-Amino Acids. On heating two moles of an a-amino acid, such as alanine, in the presence of a tetraalkyl titanate and an alcohol, reaction that gives a 2,5-pipetazineclione and an oxytitanate occurs (36). [Pg.142]

Amino Alcohols. Reaction of chloroformate is much more rapid at the amino group than at the hydroxyl group (4—8). Thus the hydroxy carbamates, which can be cyclized with base to yield 2-oxazoHdones, can be selectively prepared (29). Nonionic detergents may be prepared from poly[(ethylene glycol) bis(chloroformates)] and long-chain tertiary amino alcohols (30). [Pg.39]

However, this method is appHed only when esterification cannot be effected by the usual acid—alcohol reaction because of the higher cost of the anhydrides. The production of cellulose acetate (see Fibers, cellulose esters), phenyl acetate (used in acetaminophen production), and aspirin (acetylsahcyhc acid) (see Salicylic acid) are examples of the large-scale use of acetic anhydride. The speed of acylation is greatiy increased by the use of catalysts (68) such as sulfuric acid, perchloric acid, trifluoroacetic acid, phosphoms pentoxide, 2inc chloride, ferric chloride, sodium acetate, and tertiary amines, eg, 4-dimethylaminopyridine. [Pg.380]

In actual practice, catalysts are usually employed to catalyze the isocyanate/ alcohol reaction at room temperature. Typical catalysts for this reaction are the tin(IV) salts, e.g., dibutytin dilaurate, or tertiary amines, such as triethylene diamine [2]. [Pg.762]

Chemical Reactivity - Reactivity with Water Slow reaction to form formic acid and methyl alcohol reaction is not hazardous Reactivity with Common Materials No reaction Stability During Transport Stable Neutralizing Agents for Acids and Caustics Not pertinent Polymerization Not pertinent Inhibitor of Polymerization Not pertinent. [Pg.261]

TABLE 1-4 Effect of Iron on the Rate of Alkali Metal-Alcohol Reactions in Liquid Ammonia"- ... [Pg.20]

A remarkable feature of the Birch reduction of estradiol 3-methyl ether derivatives, as well as of other metal-ammonia reductions, is the extreme rapidity of reaction. Sodium and -butyl alcohol, a metal-alcohol combination having a comparatively slow rate of reduction, effects the reduction of estradiol 3-methyl ether to the extent of 96% in 5 minutes at —33° lithium also effects complete reduction under the same conditions as is to be expected. Shorter reaction times were not studied. At —70°, reduction with sodium occurs to the extent of 56 % in 5 minutes, although reduction with lithium is virtually complete (96%) in the same time. (The slow rates of reduction of compounds of the 5-methoxytetralin type is exemplified by 5-methoxy-tetralin itself with sodium and f-butyl alcohol reduction occurs to the extent of only 50% in 6 hours vs. 99+% with lithium.) The iron catalyzed reaction of sodium with alcohols must be very fast since it competes so well with the rapid Birch reduction. One cannot compensate for the presence of iron in a Birch reduction mixture containing sodium by adding additional metal to extend the reaction time. The iron catalyzed sodium-alcohol reaction is sufficiently rapid that the aromatic steroid still remains largely unreduced. [Pg.22]

Toluene from Toluidine.—It is often desirable to obtain tbe hydiocarbon from the base. The process of diazotisntion offers the only convenient method. The diazonium salt may be reduced by alcohol (Reaction 1, p. 162) or, as in the piesent instance, by sodium stannite. Less direct methods are the con-veision of the diazonium compound into (i) the hydrazine (see p. 174), (2) the acid and distillation with lime (p. 200), (3) the halogen derivative and reduction with sodium amalgam, 01, finally (4) the phenol and distillation with zinc dust. [Pg.284]

Dependence of apparent constants on concentration. We continue the consideration of Scheme XXIII by making chemically reasonable tentative selections of the forms of A a and k[. First, consider the acetyl chloride-alcohol reaction. Because the spectral observations show that intermediate formation is essentially complete, this system belongs to the case in which kdk i may be treated as infinite (Scheme XXIV). The observed reaction is then... [Pg.121]

The use of sodium tribromoacetate as the dibromocarbene precursor has been investigated and found to provide the Ciamician-Dennstedt product in higher yield than the traditional alkoxide/alcohol reaction conditions. Deprotonation of bromoform with sodium ethoxide in ethanol and reaction of the resultant carbene with 6 provides quinoline 9 in 9% yield thermolysis of sodium tribromoacetate in the presence of 6 furnishes 9 in 20% yield (Scheme 8.3.3). [Pg.351]

N-Benzylacetamide, 43,18 n-Benzylacrylauide, 42,16 Benzyl alcohol, reaction with acrylonitrile, 42, 16... [Pg.107]

Acid anhydride-diol reaction, 65 Acid anhydride-epoxy reaction, 85 Acid binders, 155, 157 Acid catalysis, of PET, 548-549 Acid-catalyzed hydrolysis of nylon-6, 567-568 of nylon-6,6, 568 Acid chloride, poly(p-benzamide) synthesis from, 188-189 Acid chloride-alcohol reaction, 75-77 Acid chloride-alkali metal diphenol salt interfacial reactions, 77 Acid chloride polymerization, of polyamides, 155-157 Acid chloride-terminated polyesters, reaction with hydroxy-terminated polyethers, 89 Acid-etch tests, 245 Acid number, 94 Acidolysis, 74 of nylon-6,6, 568... [Pg.575]

Alcohols, reaction of isocyanates with, 224-225 Alcoholysis, 69 Alicyclic dianhydrides, 297 Alignment coating, for liquid crystal devices, 269-270 Aliphatic AA-BB-type polyamides, synthesis of, 164-173 Aliphatic AB-type polyamides, 173-180 Aliphatic acids, 60... [Pg.576]

There are also useful procedures for preparation of azides directly from alcohols. Reaction of alcohols with 2-fluoro-l-methylpyridinium iodide followed by reaction with lithium azide gives good yields of alkyl azides.75... [Pg.232]

Disulfiram works by irreversibly blocking the enzyme aldehyde dehydrogenase, a step in the metabolism of alcohol, resulting in increased blood levels of the toxic metabolite acetaldehyde. As levels of acetaldehyde increase, the patient experiences decreased blood pressure, increased heart rate, chest pain, palpitations, dizziness, flushing, sweating, weakness, nausea and vomiting, headache, shortness of breath, blurred vision, and syncope. These effects are commonly referred to as the disulfiram-ethanol reaction. Their severity increases with the amount of alcohol that is consumed, and they may warrant emergency treatment. Disulfiram is contraindicated in patients who have cardiovascular or cerebrovascular disease, because the hypotensive effects of the disulfiram-alcohol reaction could be fatal in such patients or in combination with antihypertensive medications. Disulfiram is relatively contraindicated in patients with diabetes, hypothyroidism, epilepsy, liver disease, and kidney disease as well as impulsively suicidal patients. [Pg.543]


See other pages where Alcohol reaction is mentioned: [Pg.79]    [Pg.179]    [Pg.90]    [Pg.86]    [Pg.21]    [Pg.352]    [Pg.161]    [Pg.799]    [Pg.43]    [Pg.84]    [Pg.61]    [Pg.75]    [Pg.61]    [Pg.291]    [Pg.159]    [Pg.173]    [Pg.156]    [Pg.164]    [Pg.217]    [Pg.207]    [Pg.89]   
See also in sourсe #XX -- [ Pg.323 , Pg.331 ]

See also in sourсe #XX -- [ Pg.36 , Pg.37 , Pg.38 , Pg.39 , Pg.40 , Pg.41 , Pg.42 , Pg.43 , Pg.44 , Pg.45 , Pg.46 , Pg.47 , Pg.48 ]

See also in sourсe #XX -- [ Pg.83 ]

See also in sourсe #XX -- [ Pg.83 , Pg.93 ]

See also in sourсe #XX -- [ Pg.341 , Pg.342 , Pg.343 , Pg.344 , Pg.345 ]

See also in sourсe #XX -- [ Pg.518 , Pg.519 , Pg.520 , Pg.521 , Pg.522 , Pg.523 , Pg.524 , Pg.525 , Pg.526 , Pg.527 , Pg.528 , Pg.529 , Pg.530 , Pg.531 , Pg.532 , Pg.533 , Pg.534 ]

See also in sourсe #XX -- [ Pg.518 , Pg.519 , Pg.520 , Pg.521 , Pg.522 , Pg.523 , Pg.524 , Pg.525 , Pg.526 , Pg.527 , Pg.528 , Pg.529 , Pg.530 , Pg.531 , Pg.532 , Pg.533 , Pg.534 ]

See also in sourсe #XX -- [ Pg.253 , Pg.254 , Pg.255 , Pg.264 , Pg.278 , Pg.279 ]

See also in sourсe #XX -- [ Pg.57 ]

See also in sourсe #XX -- [ Pg.476 , Pg.478 ]

See also in sourсe #XX -- [ Pg.640 ]

See also in sourсe #XX -- [ Pg.512 , Pg.513 ]

See also in sourсe #XX -- [ Pg.1294 , Pg.1295 , Pg.1295 , Pg.1296 , Pg.1297 , Pg.1298 ]




SEARCH



© 2024 chempedia.info