Vitamin Bi Hydrochloride

Aneurine Hydrochloride Thiamine Chloride Vitamin Vitamin Bi Hydrochloride... 

Thiamine hydrochloride (vitamin Bi hydrochloride, HC12-H17ON4SCI2) is a weak acid with = 3.4 X 10. Suppose 3.0 X 10 g of thiamine hydrochloride is dissolved in 1.00 L of water. Calculate the pH of the resulting solution. [Hint This is a sufficiently dilute solution that the autoionization of water cannot be neglected.)... 

Synonyms Aneurine hydrochloride Thiamin chloride Thiamine chloride hydrochloride Thiamine dichloride Thiamine hydrochloride Thiamin hydrochloride Thiaminium chloride hydrochloride Vitamin Bi hydrochloride Definition Chloride-hydrochloride salt of thiamine Empiricai C12H18CI2N4OS Formuia C12H17CIN4OS HCI Properties Small wh. cryst. orcryst. powd., nut-like odor sol. in water, glycerol si. sol. in alcohol insol. in ether, benzene m.w. 337.30 m.p. 248 C (dec.)... 

Vitamin Bi hydrochloride. See Thiamine HCI Vitamin Be hydrochloride. See Pyridoxine HCI Vitamin E linoleate. See Tocopheryl linoleate Vitamin Bi mononitrate. See Thiamine nitrate Vitamin E nicotinate. See Tocopheryl nicotinate d-a-Tocopheryl nicotinate Vitamin Bi nitrate. See Thiamine nitrate Vitamin P. See Hesperidin Rutin Vitamin B2 phosphate. See Riboflavin 5 -phosphate. 

Description of Method. The water-soluble vitamins Bi (thiamine hydrochloride), B2 (riboflavin), B3 (niacinamide), and Be (pyridoxine hydrochloride) may be determined by CZE using a pH 9 sodium tetraborate/sodlum dIhydrogen phosphate buffer or by MEKC using the same buffer with the addition of sodium dodecyl-sulfate. Detection Is by UV absorption at 200 nm. An Internal standard of o-ethoxybenzamide Is used to standardize the method. 

See also Vitamin Bi Thiamine deficiency, 26 291 Thiamine hydrochloride, 25 795 Thiamine hydrochloride... 

The interaction of metal ions with vitamin Bi (thiamine hydrochloride, 135) continues to be of interest, and a combination of IR, XH and 13C NMR techniques have been applied to the... 

Thiamine hydrochloride (C12H18ON4SCI2) is a water-soluble form of thiamine (vitamin Bi K. = 3.37X10 ). How many grams of the hydrochloride must be dissolved in 10.00 mL of water to give a pH of 3.50 ... 

Wl. Wachstein, M., and Gudaitis, A., Disturbance of vitamin Bi metabolism in pregnancy. II. The influence of various amounts of pyridoxine hydrochloride upon die abnormal tryptophan load test in pregnant women. J. Lab. CUn. Med. 42, 98-107 (1953). 

The dehydration of a thiamine hydrochloride (vitamin Bi) hydrate, commonly referred to as the monohydrate, was investigated by solid state NMR and X-ray diffraction. The hydrate was classified as a nonstoichiometric solvate since the water content depends on the water vapor pressure of the surrounding atmos-... 

Supplement vitamin Bi deficiency states, impaired absorption or increased requirements (pregnancy, lactation, alcoholism) Therapy beriberi, Wernicke s encephalopathy, neuritis, polyneuritis (alcoholic and toxic), neuralgia, myalgia, myocardia, disorders of the intermediate metabolism Thiamine chloride and hydrochloride, thiamine mononitrate, cocarboxylase, thiamine pyrophosphate Tablets, sugar-coated pills, dragees, ampules 50-300 mg 0.3-1.2 mg 1.0-1.4 mg... 

CAS 58-56-0 EINECS/ELINCS 200-386-2 Synonyms Adermine hydrochloride 3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine HCI 3-Hydroxy-4,5-dimethylol-a-picoline hydrochloride 5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride 2-Methyl-3-hydroxy-4,5-bis (hydroxymethyl) pyridine hydrochloride Pyridoxine hydrochloride Pyridoxinium chloride Pyridoxinum hydrochloride Pyridoxol hydrochloride Vitamin Be hydrochloride Classification Substituted aromatic compd. Empirical CsHnNOs CIH Properties Colorless to wh. platelets or cryst. powd., odorless sol. in water, alcohol, acetone, propylene glycol si. sol. in other org. soivs. insol. in ether, chloroform m.w. 205.66 m.p. 204-206 C (dec.) pH 2.0-3.5 (5% aq.)... 

The quantitative analysis of thiamine hydrochloride (vitamin Bi), using HPTLC on sUica gel plates with two different mobile phases, was elaborated. After TLC separation, vitamin Bi was derivatized by the use of tert-butyl hypochlorite or potassium hexacyanoferrate (ni)-sodium hydroxide as reagents. The tert-butyl hypochlorite reagent formed yeUow-fluorescing derivatives... 

Funk, W. Derr, P. Characterization and quantitative HPTLC determination of vitamin Bi (thiamine hydrochloride) in a pharmaceutical product. J. Planar Chromatogr. 1990, 3, 149-152. 

Vitamin Bi [1] exists in nature both in free (thiamin) and esterified form (thiamin monophosphate, diphosphate, and triphosphate), while thiamin hydrochloride is used as a supplement [4]. To evaluate the total content of vitamin Bi in a food, extraction usually consists of an acid hydrolysis (0.1 M HCl in a water bath at 100°C or in an autoclave at 121°C) followed by an enzymatic digestion (diastases possessing a phosphatase activity) [1,2,5,6]. The acid treatment frees protein-boimd forms and converts starch into soluble sugars. The enzymatic treatment may require several hours (on average 3 hr) of incubation for complete dephosphorylation of the thiamin esters. 

Cysteine hydrochloride, nicotinic acid, pantothenic acid plus glycine, pteroylglutamic acid plus p-aminobenzoic acid, and methionine were added in final concentrations of 50, 5, 0.5, and 0.06 iig, per milliliter with and without vitamin Bu, 5 Hfig. per milliliter. Nicotinic acid, 50 Mg. per milliliter, was completely inhibitory, while 6 Mg. per milliliter was not. Pteroylglutamic acid, p-aminobenzoic acid, pyridoxine hydrochloride, glycine, pantothenic acid, and uracil in concentrations of 0.5 Mg. per milliliter without vitamin Bis, and 50, 5, 0.5, and 0.05 Mg. per milliliter with vitamin Bis, 6 nng. per milliliter, were also tested. Ethyl alcohol (12.5%, 2.5%, 0.25%, 0.026%, and 0.0025%) and ammonium hydroxide (5%, 0.5%, 0.05%, and 0.005%) with and without vitamin Bis, 5 MMg- per milliliter, were tested because of their use in dissolving some of the substances listed above. Ethyl alcohol, 12.5% but not 2.6%, and 5% ammonium hydroxide, but not 0.5%, were inhibitory. Leuconostoc citrovorum factor (folinic acid), 75 Mg. per milliliter, did not replace vitamin Bis. 

Synonyms Adermine hydrochloride 3-Hydroxy4,5-dihydroxymelhyl-2-methylpyri-dine HCI 3-Hydroxy4,5-dimelhylol-a-picoline hydrochloride 5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride 5-Hydroxy-6-melhyl-3,4-pyridinedimelhanol hydrochloride 2-Methyl-3-hydroxy4,5-bis (hydroxymethyl) pyridine hydrochloride Pyridoxine hydrochloride Pyridoxinium chloride Pyridoxi-num hydrochloride Pyridoxol hydrochloride Vitamin Bg hydrochloride Classification Substituted aromatic compd. 

Hydroxy-2-methyl-4,5-bis-[hydroxymethyl -pyridin-Hydrochlorid (Vitamin B6)8... 

Pyridoxine (peer-ih-DOCK-seen) is also known as 3-Hydroxy-4,5-bis(hydroxymethyl)- -methyl pyridine 3-hydroxy-4,5-dime-thylol-2-methylpyridine and vitamin B6. It is a white, odorless, crystalline compound with a slightly bitter taste. The term pyridoxine is also used as a generic term for three compounds with biological activity classified under the term Vitamin Bfc. The three compounds are pyridoxine, pyridoxal, and pyridoxamine. Pyridoxine is usually produced commercially as the hydrochloride, CH3CSHN(0H)(CH20H)2-HC1, which has somewhat different physical characteristics from pyridoxine itself. 

Vitamin hydrochloride (adermine, pyridoxine HCl, 3-hydroxy, 5-bis[hydroxymethyl]-2-... 

Figure 14.1 presents chromatograms of vitamins analysed in fruit drinks. The detection limit for thiamine hydrochloride deteetion was 9.2 ng/ml, whereas the limits for pyridoxine and cyanoeobalamin were 2.7 and 0.08 ng/ml, respectively. The proposed separation and detection procedure was applied sueeess-fully for quantitative evaluation of the studied B vitamins in pharmaeeutieal preparations and dietary supplements, and for routine control of multivitamin enriched foods. Based on those sueeessful results, we have developed also a method for analysis of vitamins Bg, B12 and Bi in seafood produets (Lebiedzinska et al. 2007). 

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