Vancomycin chromatography

Ghassempour, A., Darbandi, M.K., and Asghari, F.S., Comparison of pyrolysis-mass spectrometry with high performance liquid chromatography for the analysis of vancomycin in serum, Talanta, 55, 573, 2001. 

Backes, D.W., Aboleneen, H.I., and Simpson, J.I., Quantitation of vancomycin and its crystalline degradation product (CDP-1) in human serum by high performance liquid chromatography, 7. Pharm. Biomed. Anal., 16, 1281, 1998. 

Ghassempour, A. et al., Crystalline degradation products of vancomycin as a new chiral stationary phase for liquid chromatography, Chromatographia, 61, 151, 2005. 

Donnecke, J. et ah. Evaluation of a vancomycin chiral stationary phase in packed capillary supercritical fluid chromatography, J. Microcol. Sep., 11, 521, 1999. 

Svensson, L.A. et ah. Vancomycin-based chiral stationary phases for micro-column liquid chromatography. Chirality, 11, 121, 1999. 

Kang, W. et ah. Analysis of benidipine enantiomers in human plasma by liquid chromatography—mass spectrometry using a macrocyclic antibiotic (vancomycin) chiral stationary phase column, J. Chromatogr. B, 814, 75, 2005. 

Pihlainen, K. and Kostiainen, R., Effect of the eluent on enantiomer separation of controlled drugs by liquid chromatography-ultraviolet absorbance detection-electrospray ionisation tandem mass spectrometry using vancomycin and native fi-cyclodextrin chiral stationary phases, J. Chromatogr. A, 1033, 91, 2004. 

Bosakova, Z., Cufinovd, E., and Tes ovd, E., Comparison of vancomycin-based stationary phases with different chiral selector coverage for enantioselective separation of selected drugs in high-performance liquid chromatography, J. Chromatogr. A, 1088, 94, 2005. 

Bosikova, Z., Klouhkova, 1., and Tesafova, E., Study of the stability of promethazine enantiomers by liquid chromatography using a vancomycin-bonded chiral stationary phase, J. Chromatogr. B, 770, 63, 2002. 

Kang, J. W., Van Schepdael, A., Roets, E., and Hoogmartens, J. (2001). Analysis of vancomycin and related impurities by micellar electrokinetic capillary chromatography. Method development and validation. Electrophoresis 22, 2588—2592. 

Bhushan and Parsad [65] resolved dansyl amino acids on erythromycin impregnated thin-layer chromatographic (TLC) silica plates. The mobile phase used was different ratios of 0.5 M aqueous NaCl-acetonitrile-methanol. Further, Bhushan and Thiong o [66] achieved the chiral resolution of dansyl amino acids on silica TLC plates impregnated with vancomycin chiral selector. The mobile phase used for this study was acetonitrile-0.5 M aqueous NaCl (10 4 and 14 3, v/v). The chiral recognition mechanisms of antibiotic CSPs in sub-SFC, SFC, CEC, and TLC modes of chromatography were found to be similar to HPLC. 

Although the macrocyclic glycopeptide antibiotic CSPs are very effective for the chiral resolution of many racemic compounds, their use as chiral mobile phase additives is very limited. Only a few reports are available on this mode of chiral resolution. It is interesting to note that these antibiotics absorb UV radiation therefore, the use of these antibiotics as the CMPAs is restricted. However, Armstrong et al. used vancomycin as the CMPA for the chiral resolution of amino acids by thin-layer chromatography, which will be discussed in Section 10.7. 

EDTA in vancomycin by liquid chromatography with absorbance ratioing for peak identification, J. Pharm. Biomed. Anal., 5 513 (1990). 

M. Mathew and V. DasGupta, Stability of vancomycin hydrochloride solutions at various pH values as determined by high-performance liquid chromatography, Drug Dev. Ind. Pharm., 27 100 (1994). 

With CsF in DMSO at room temperature, the ring closure to the (/f)-configured M(2-4) atropisomer 14a was achieved in a yield of 95 % with a diastereoselectivity of 5 1. Detailed examinations of Evans et al. reveal that the diastereoselectivity of this M(2-4) cyclization is controlled by the natural conformation of the M(5-7) macrocycle [3]. The final functionalization to the chlorine-containing, protected vancomycin aglycon includes a chromatographic separation of the mixture of atropisomers by column chromatography. 

For the separation of anionic analytes, the positively charged macrocyclic antibiotic vancomycin is one of the most commonly used chiral selectors. It was introduced by Armstrong and coworkers as a new class of chiral selector in CE, HPLC and thin-layer chromatography for the separation of a wide range of enantiomers [29, 47-52]. It contains multiple stereogenic centers and a variety of functional groups. 

Khalfi, F., Dine, T., Gressier, B., Luyckx, M., Brunet, C., Ballester, L., Goudaliez, F., Cazin, M., and Cazin, J.C. (1996) Comparability and stability of vancomycin hydrochloride with PVC infusion material in various conditions using stability-indicating high-performance liquid chromatography assay, Int. J. Pharm., 139, 243-247. 

Paap, C.M. Nahata, M.C. A novel micromethod for the simultaneous analysis of cefotaxime and desa-cetylcefotaxime from plasma using ion pair high performance liquid chromatography. J.Liq.Chromatogr., 1989, 12, 2385-2395 [plasma cefoxitin (IS) also acetaminophen, caffeine, cefazolin, methicillin, theophylline, vancomycin non-interfering ampicillin, gentamicin, ibuprofen, phenobarbital]... 

Li, L. Miles, M.V. Hall, W. Carson, S.W. An improved micromethod for vancomycin determination by high-performance liquid chromatography. Ther.Drug Monit., 1995, 17, 366-370... 

Najjar, T.A. Al-Dhuwailie,.A. Tekle, A. Comparison of high-performance liquid chromatography with fluorescence polarization immunoassay for the analysis of vancomycin in patients with chronic renal failure. J.Chromatogr.B, 1995, 672, 295-299... 

Jehl, F, Gallion, C. Thierry, R.C. Monteil, H. Determination of vancomycin in human serum by high-pressure liquid chromatography. Antimicrob.Agents Chemother., 1985, 27, 503-507... 

McClain, J.B. Bongiovanni, R. Brown, S. Vancomycin quantitation by high-performance liquid chromatography in human serum. J.Chromatogr., 1982, 231, 463—466... 

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