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Transforming growth factors and

Date M et al. Differential expression of transforming growth factor-/ and its receptors in hepatocytes and nonparenchy-mal cells of rat liver after CC14 administration. J Hepatol 1998 28 572-581. Frueh FW et al. Extent and character of Phenobarbital-mediated changes in gene expression in the liver. Mol Pharmacol 1997 51 363-369. [Pg.117]

You S, Thieblemont N, Alayankian MA, Bach J, Chatenoud L. 2006. Transforming growth factor-) and T-cell-mediated immunoregulation in the control of autoimmune diabetes. Immunol Rev. 212 185-202. [Pg.226]

Khalil, N., Bereznay, O.H., Spom, M. and Greenberg, A.H. (1989). Macrophage production of transforming growth factor and fibroblast collagen synthesis in chronic pulmonary inflammation. J. Exp. Med. 170, 727-737. [Pg.222]

Okuda S, Languino LR, Ruoslahti E, Border WA. 1990. Elevated expression of transforming growth factor-/ and proteoglycan production in experimental glomerulonephritis possible role in expansion ofthe mesangial extracellular matrix. J. Clin. Invest. 86 453-62... [Pg.90]

Lyons RM, Moses HL. 1990. Transforming growth factors and the regulation of cell proliferation. Eur. J. Biochem. 187 467-73... [Pg.90]

The plasma concentration of calcium is kept remarkably constant throughout life at about 8.8-10.3 mg/dL (2.20-2.58 mmol/L). The normal serum calcium concentration is maintained by the integrated actions of parathyroid hormone (PTH) vitamin D metabolites, calcitonin, and cytokines such as transforming growth factor and interleukin-6. The principal target sites for these hormones... [Pg.873]

Several growth factors have been isolated from kidney tissue. They include, among others, epidermal growth factor, insulin-tike growth factors, transforming growth factors, and platelet-derived growth factor. [Pg.640]

S. Increased synthesis of transforming growth factor-beta , which blocks cell division and promote.s apoptosis by interacting with its own membrane recepror,... [Pg.285]

Bottner M, Krieglstein K, Unsicker K (2000) The transforming growth factor-(3s structure, signaling, and roles in nervous system development and functions. J Neurochem 75 2227-2240... [Pg.845]

In the interstitium, angiotensin II induces proliferation of mesangial cells and fibroblasts and the synthesis of collagen and other matrix molecules by these cells via the ATI receptor. Moreover, by the concomitant stimulation of chemoattractant cytokines, inflammation is induced. These processes are mediated by endothelin, transforming growth factor(3, and reactive oxygen species, and finally lead to interstitial fibrosis and glomerulosclerosis observed in hypertension and diabetes. [Pg.1067]

Hyperphosphorylation of ERAK-1 by itself and ERAK-4 causes ERAK-1 to dissociate from the membrane-bound complex. Tumour necrosis factor (TNF) receptor-associated factor-6 ( TRAF-6), a cytoplasmic protein, is activated by ERAK-1 and with TAB-2, another cytoplasmic protein, activates transforming growth factor-P (TFG-P)-activating kinase (TAK-1). During this process both TRAF-6 and TAK-1 become ubiquitinated. TAK-1 then promotes activation of the IkB kinases, or the IKK family, EKKa and EKK 3 (found in a complex with NFicB-essential modulator [NEMO]), which phosphorylate the IkB family, notably IkB-u. IkB-u is an inhibitor of NFkB as it sequesters NFkB in an... [Pg.1208]

Transforming growth factor-beta (TGF- 3) proteins are multifunctional morphogens that control cell proliferation, differentiation and apoptosis, as well as cell migration and immune surveillance. TGF-(3 acts as a tumor suppressor, but can also act as a tumor promoter in... [Pg.1229]

Danielpour D (2005) Functions and regulation of transforming growth factor-beta (TGF-beta) in the prostate. Eur J Cancer 41 846-857... [Pg.1233]

Mishra L, Derynck R, Mishra B (2005) Transforming growth factor-beta signaling in stem cells and cancer. Science 310 68-71... [Pg.1233]

Faler BJ, Macsata RA, Plummer D et al (2006) Transforming growth factor-beta and wound healing. Perspect Vase Surg Endovasc Ther 18(1) 55—62... [Pg.1233]

Flanders, K.C., Winokur, T.S., Holder, M.G., Spom, M.B. (1993). Hyperthermia induces expression of transforming growth factor beta in rat cardiac cells in vitro and in vivo. J. Clin. Invest. 92, 404-410. [Pg.453]

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See also in sourсe #XX -- [ Pg.236 , Pg.237 ]



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Transformation growth factors

Transforming growth factors

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