TO-PRO

CA Index Name Quinolinium, 4-[3-(3-methyl-2(37/)-benzothiazolylidene)-1 -propen-1 -yl] -1 -[3-(trimethylammonio)propyl]-, iodide (1 2) 

Imaging/Labeling Applications Nucleic acids cells nuclei bacteria - leukocytes liposomes microorganisms reticulocytes - sperms 

Industrial Applications Not reported Safety/Toxicity No data available 

Sabnis, R. W. Handbook of Biological Dyes and Stains-, John Wiley Sons Inc. Hoboken, 2010 pp 477 78. 

Johnson, I. D. Huang, Z. Haugland, R. P. Unsymmetrical cyanine dyes with a cationic side chain. U.S. Patent 5321130,1994. 

Staining Applications Nucleic acids cells antihodies bacteria leukocytes nuclei megakaryocyte microorganisms peptides pro-teins reticulocytes sperms  

Burton, D. R. Chamberlain, C. Labeled peptides, proteins and antibodies and processes and intermediates useful for their 

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This will work just as well in converting benzaldehyde to pro-penylbenzene as it will in converting piperonal. This is like the millionth method Strike has pulled from the reference 19. This was the most street-applicable article Strike has ever come across, but the greatest thing about this article s recipes is that THEY WORK Strike means to say they work big time A lot of this has to do, no doubt, with the fact that the most accomplished amphetamine chemists co-authored the work Drs. Shulgin and Nichols. 

According to the Arrhenius definitions an acid ionizes m water to pro duce protons (H" ) and a base produces hydroxide ions (HO ) The strength of an acid is given by its equilibrium constant for ionization m aqueous solution... 

Organolithium reagents (Section 14 3) Lithi um metal reacts with organic halides to pro duce organolithium compounds The organic halide may be alkyl alkenyl or aryl Iodides react most and fluorides least readily bro mides are used most often Suitable solvents include hexane diethyl ether and tetrahy drofuran... 

Pig. 3. Representation of promoter sites on the pro-enkephalin gene. The numbers represent the distance in nucleotides from the pro-enkephalin initiation codon the arrow indicates the direction of transcription. The TATA promoter box occurs immediately before the pro-enkephalin initiation site the AP-2 site, which binds immediate-early gene products, is 70 nucleotides upstream, and the CRE site, which binds a regulatory protein involved in cAMP induction of mRNA synthesis, is 107 nucleotides upstream from the initiation codon. The expanded section shows that the CRE site actually consists of two elements, ENKCRE-1 and ENKCRE-2, which separately confer cAMP sensitivity to pro-enkephalin mRNA synthesis. 

For positive displacement pumps, a bypass-type control valve should be furnished to set the primary lube system pressure. The valve should be able to maintain system pressure during pump startup and pump transfers, which includes relieving the capacity of one pump, while both are running. The valve should provide stable, constant pressure during these transients. Flow turndown of 8 to 1 is not unusual. Multiple valves in parallel should be used if a single valve is not suitable. The valve should be sized to operate between 10 and 90% of the flow coefficient (Cv). Additional pressure control valves should be furnished as required to pro ide any of the intermediate pressure levels. 

Select the optimal ventilation method to reduce emissions and/or to pro tect workers. (For details, see the subtree Fig.. 3.10.)... 

Cilia Hair-like motile extensions of a cell wall. Airway cells use cilia to pro-... 

Transformation products of stabilizers formed during melt processing may exert either or both anti- and/ or pro-oxidant effects. For example, in the case of BHT, peroxydienones, PxD (reactions 9b, b") lead to pro-oxidant effects, due to the presence of the labile peroxide bonds, whereas quinonoid oxidation products, BQ, SQ, and G- (reaction 9 b, c, d) are antioxidants and are more effective than BHT as melt stabilizers for PP [29], The quinones are effective CB—A antioxidants and those which are stable in their oxidized and reduced forms (e.g., galvinoxyl, G-, and its reduced form, hydrogalvi-noxyl, HG) may deactivate both alkyl (CB—A mecha-... 

Many review have documented the utilization of ylides in synthetic organic chemistry [10]. This chapter focuses on recent developments and special topics of ylide polymer science. The major purpose of this review is to pro-... 

Rupture disks are often placed below a safety valve to prevent corrosive, tarring or other material from entering the valve nozzle. Only disks which do not disintegrate when they burst (Figures 7-10, 7-11, 7-12, 7-18) can be used below a safety valve, as foreign pieces which enter the valve might render it useless. This is acceptable to certain code applications [1]. These disks are also used to pro dde secondary relief when in parallel tvith safety valves set at lower pressures. They can also be installed on the discharge of a safety valve to prevent loss of hazardous vapors, but caution should be used in anv serious situation. 

To pro dde some external protection against the damage that an external lire can do to a pressure relief valve or rupture disk, this author recommends that these devices be insulated after installation in such a manner as not to restrict their action but to provide some measure of reliable performance, even if the vessel is not insulated. 

Flares are an attempt to deliberately burn the flammable safety relief and/or process vents from a plant. The height of the stack is important to the safety of the surroundings and personnel, and the diameter is important to provide sufficient flow velocity to allow the vapors/ gases to leave the top of the stack at sufficient velocities to pro ide good mixing and dilution after ignition at the flare tip by pilot flames. 

E Transcription is the process by which RNA is produced to carry genetic information from the nucleus to the ribosomes. A short segment of the DNA double helix unwinds, and complementary ribonucleotides line up to pro-... 

With regard to pro pints, brisance, power and detonation velocity are not tested. It is, however, necessary to determine the burning rate, press developed on burning, vol of gas evolved, calorific value, thermal stability, etc. If one is... 

Gem-dihydroperoxide (2), > /O-OH C no-oh W sol and decomp slowly with evoln of 02 and formation of expl polymeric peroxides can be reduced and hydrolyzed thermal decompn leads to pro- orpccivp Vinn/1 plptivacrp nf —0—0—, C—0— and then C—C bonds Polymeric peroxides formed as a decompn product are extremely expl... 

The application of 3-aminopropyl phosphine (3) [41,46] as a building block for incorporation into -COOH functionalized frameworks provides an excellent example of the utility of preformed primary phosphine frameworks (Scheme 8) [46]. The reactions involved Michael addition of ferf-butyl acrylate to malonic acid dimethyl ester to produce the intermediate adduct, 2-methoxycarbonyl-pentanedioc acid 5-ferf-butyl ester 1-methyl ester, which upon treatment with trifluro-acetic acid (TFA) produced the corresponding diester acid,2-methoxy-carbonyl-pentanedioic acid 1-methyl ester, in near quantitative yield. It is remarkable to note that the reaction of NH2(CH2)3PH2 (3) with the diester acid is highly selective as the -COOH group remained unattacked whereas the reaction occurred smoothly and selectively at the -COOMe groups to pro-... 

Small regions of the protein make direct contact with DNA the rest of the protein, in addition to pro-... 

Figure 4 Sequential assignment of the backbone atoms for the segment Pro-109 to Val-113 of inhibited sfSTR by 4-D HCANNH and 4-D HCA(CO)NNH. Four planes are shown from each spectrum. The assigned backbone atoms are indicated in (A). In (B) the upper four planes in solid lines are from the 4-D HCANNH and the lower four planes in dashed lines are from the 4-D HCA(CO)NNH. The chemical shifts for the four correlated nuclei in each case are shown. The correlations continue for the segment Pro-109 to Pro-129. As Pro lacks a protonated N, this residue serves as a "stop" signal. The correlation of 19 residues with Pro at the N- and C-terminal ends is unique for this segment in the sequence of sfSTR, therefore these backbone atoms are specifically assigned without having to further assign side chain atoms. (From Ref. 5.)...

The fund managing institute, in consultation would approve the disbursement of funds to PROs based on the feasibility of proposals received by the state agencies from prospective organizations. 

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