Methods of testing

UNIFAC was developed for situations where experimental data are scarce, and its appHcation should generally be that of last resort (3,7,162,178). That is, UNIFAC is not a method for comparative testing of methods based on experimental data even though the method is sometimes Hsted in commercial computer simulator menus without indication of its limitations. 

System suitability. During the robustness testing of method validation, critical method parameters such as mobile phase composition and column temperature are varied to mimic the day-to-day variability. Therefore, the system suitability results from these robustness experiments should reflect the expected range for the system suitability results. As a result, system suitability results in these method validation experiments are very useful in determining the system suitability... 

I would like to thank Dr. Ed Canning and Mrs. Marian McNeil (Scottish Agricultural Science Agency) for the development and testing of methods presented in this work. 

III. Further Development and Testing of Methods, Ministry for Foreign Affairs of Finland, Helsinki, 1987. 

M. Rautio (Ed.), Air Monitoring as a Means for the Verification of Chemical Disarmament, C.4. Further Development and Testing of Methods, Part III, The Ministry for Foreign Affairs of Finland, Helsinki, 1987, 95-96. 

USEPA (1997a). Round-Robin Testing of Methods for Collecting Dislodgeable Residues from Carpets, Report No. 600/R-97/119, National Exposure Research Laboratory, Research Triangle Park, NC, USA. 

Once the method is vahdated, any modification requires revalidation to demonstrate that it still works as defined. If the new parameter is within the tolerance range of the method as specified during the ruggedness test of method validation, the method does not need to be revalidated. In other cases, it should go through revalidation. With the system suitability software frequently offered by analytical equipment vendors, methods can be automatically revalidated with little operator interaction. The validation can be performed overnight. 

Computational results a test of methods and a source of suggestion about their use. 

It can be easily seen from this incomplete listing of rules and principles that are of importance in one or the other situation, that there are certain similarities between different quality systems, but that grave differences do also exist. There are still other differences which have to be considered when trying to determine the connections and similarities or dissimilarities between various quality systems. Where the emphasis lies on precision and reproducibility, with consideration of reproducibility not only within one laboratory but between several laboratories, then the testing of methods in ring tests, with regard to their repeatability and robustness, will gain in importance. This is certainly possible for tests where the environmental conditions can be accurately controlled, like in an analysis by any current method. The fate of a pesticide in the environment will depend, however, on a... 

Figure 4.29 Test of method of accounting for the overlapping of iridium Lm EXAFS in the analysis of platinum Zm EXAFS data on a physical mixture of platinum and iridium and on a platinum-iridium bulk alloy (48). (Reprinted with permission from the American Institute of Physics.)...

Descy, J.P. and Coste, M. (1991) A test of methods for assessing water quality based on diatoms, Verhandlungen der Internationale VereinigungfiirTheoretische and Angewandte Limnologie. 24, pp. 2112-2116. 

Conduct pilot tests of methods of decontaminating metal parts and dunnage. 

The MTR-Phoenix Fuel Experiment is the first burnup experiment for a reactor core fueled entirely with plutonium. Thus, its reactivity time behavior with irradiation and its isotopic distributions Will provide yet a more stringent test of methods used to predict plutonium reactors. The complete set of expeitoental results including especially Uie depletion portion should be extremely important to Uiose concerned with calculating effects of even partial plutonium cores. 

The AOAC is a voluntary organization of chemists that sponsors the development and testing of methods for analyzing nutrients, foods, food and color additives, animal feeds, liquors, beverages, drugs, cosmetics, pesticides, and many other commodities. Periodically, they publish methods which are acceptable for these analyses. 

The independence of the choice of molecules is evident in that IX (the molecule intended as a test of methods of developing model intermolecu-lar potentials) included iodine, an atom whose size currently precludes the ab initio-based methods of parameterising intermolecular potentials. Coin-... 

The chemical constitution of the fly ash C2 when aluminum hydroxide and a high reactivity calcium hydroxide mixture are blown to the flue of the incinerator is shown in Table 1 together. The dissolution test of Method No. 13 was done with the substance from this fly ash C2 too. 

Lange, H., Comparative Test of Methods to Determine Particle Size and Particle Size Distribution in the Submicron Range, Part. Part. Syst. Charact., 1995, 12, 148-157. Alderliesten, M., Mean Particle Diameter, Part II Standardization ofNomenclature, Part. 

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