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Testicular germ cell cancer

Hoei-Hansen CE, Holm M, Rajpert-De Meyts E, Skakkebaek NE (2003) Histological evidence of testicular dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer. J Pathol, 200 370-374. [Pg.268]

The second most common tumor in LE is testicular germ cell cancer [43], and these patients usually harbor antibodies to the Ma2 protein. Antibodies to Ma2 antigen alone are usually associated with testicular cancer. Similar to many other onconeural antibodies, Ma2 is associated with clinical multi-focality. Many patients have symptoms of brain stem and hypothalamic dysfunction, and only one-fourth of Ma2 positive patients exhibit classical LE [45]. Patients with antibodies to the major antigen Ma2 and antibodies to Mai or Ma3 have different tumors [43, 46], and are more likely to have additional neurological signs [45],... [Pg.150]

Pont J, Albrecht W. Fertility after chemotherapy for testicular germ cell cancer. Fertil Steril 1997 68(l) l-5. [Pg.2872]

Hansen PV, Glavind K, Panduro J, Pedersen M. Paternity in patients with testicular germ cell cancer pretreatment and post-treatment findings. Eur J Cancer 1991 27(ll) 1385-9. [Pg.2872]

Christensen JF, Bandak M, Campbell A, Jones LW, Hpjman P (2015) Treatment-related cardiovascular late effects and exercise training countermeasures in testicular germ cell cancer survivorship. Acta Oncol 54 592-599... [Pg.217]

Adult Hodgkin s disease Non-Hodgkin s disease Trophoblastic choriocarcinoma Testicular and ovarian germ cell cancers... [Pg.631]

Etoposide is most useful against testicular and ovarian germ cell cancers, lymphomas, small cell lung cancers, and acute myelogenous and lymphoblastic leukemia. Toxicities include mild nausea, alopecia, allergic reaction, phlebitis at the injection site, and bone marrow toxicity. [Pg.648]

Cisplatin, combined with bleomycin and vinblastine or etoposide, produces cures in most patients with metastatic testicular cancer or germ cell cancer of the ovary. Cisplatin also shows some activity against carcinomas of the head and neck, bladder, cervix, prostate, and lung. [Pg.652]

Wilms tumor, Ewing s sarcoma, rhabdomyosarcoma, gestational choriocarcinoma, testicular tumors, lymphomas, melanomas Breast, ovarian, endometrial, bladder, thyroid cancers oat cell cancer of the lung Testicular, ovarian germ cell cancers, small-cell lung cancer, acute myelogenous and lymphoblastic leukemia... [Pg.654]

Fung MK, Cheung HW, Ling MT et al. Role of MEK/ERK pathway in the MAD2-mediated cisplatin sensitivity in testicular germ cell tumour cells. Br J Cancer 2006 95 475 84. [Pg.247]

Vinblastine is used in combination with other cytotoxic agents for the treatment of disseminated Hodgkin s disease stages III and IV, non-Hodgkin s lymphoma, histiocytic lymphoma, and advanced carcinoma of the testis. It has also been used for the treatment of bladder cancer, melanoma, and renal cell cancer. The usual adult dosage is 3-6 mg/m intravenously for the treatment of testicular germ cell tumors and Hodgkin s disease (1,2). [Pg.3632]

Marks A, Sutherland DR, Bailey D, et al. Gharacterization and distribution of an oncofetal antigen (M2A antigen) expressed on testicular germ cell tumors. Br J Cancer. 1999 80 569-578. [Pg.128]

Suijkerbuijk RE, Sinke RJ, Melon AM, et al. Overrepresentation of chromosome 12p sequences and karyotypic evolution in i(12p)-negative testicular germ-cell tumors revealed by fluorescence in situ hybridization. Cancer Genet Cytogenet. 1993 70 85. [Pg.661]

Pais V, Leav 1, Lau KM, et al. Estrogen receptor-beta expression in human testicular germ cell tumors. Clin Cancer Res. 2003 9 4475-4482. [Pg.818]

McGlynn KA, Devesa SS, Sigurdson AJ, et al. Trends in the incidence of testicular germ cell tumors in the United States. Cancer 2003 97 63-70. [Pg.2059]

Abnormal Germ Cell Development and Testicular Cancer... [Pg.91]

Unlabeled Uses Adrenocortical, bladder, cervical, endometrial, prostatic, testicular carcinomas Ewing s sarcoma multiple sclerosis non-small cell, small cell lung cancer organ transplant rejection osteosarcoma ovarian germ cell, primary brain, trophoblastic tumors rheumatoid arthritis soft tissue sarcomas systemic dermato-myositis systemic lupus erythematosus Wilms tumor... [Pg.314]

The elevations of the germ cell tumour markers P-human chorionic gonadotrophin (P-HCG), a-fetoprotein (AFP) and lactate dehydrogenase (LDH) further support the working diagnosis of testicular cancer. The levels of P-HCG and AFP in particular are negligible in males in normal circumstances, but they are raised in patients with testicular cancers as the tumours secrete these substances in large quantities. [Pg.204]

Cytotoxic chemotherapy is the cornerstone of therapy for metastatic testicular cancer. This type of cancer (known as a type of germ cell tumour as it is thought to be derived from cells in the germ cell lineage that are blocked in maturation) has been found to be extremely responsive to chemotherapeutic agents, in particular cisplatin and etoposide. There is no role for radiotherapy at this stage due to the advanced nature of the disease. [Pg.206]

ALPPL2 NM 031313 GCAP Germ cell alkaline phosphatase, GCALP Testis, malignant trophoblasts, testicular cancer Unknown... [Pg.29]

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See also in sourсe #XX -- [ Pg.707 ]

See also in sourсe #XX -- [ Pg.150 ]



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