Tanaka, Koichi

Tanaka, Koichi. (1959-).BominJapan,Tanaka won the Nobel Prize for chemistry in 2002 for his pioneering work concerning the development of methods for identification and structure analyses of biological macromolecules. Tanaka received a degree in Electrical Engineering from Tohoku University and undertakes his research at the Shimadzu Corporation. 

Tajima, Kenichi, Uchimura, Hideki, Tanaka, Koichi, Kohsaka, Shoji, Maruyama, Hiroshi. Dielectric Material Having a Low Dielectric Loss Factor for High-frequency Use. U. S. Patent, 5885916,... 

The author is grateful to his coworkers whose names appear in the references, especially Dr. Koichi Tanaka, for their many contributions. The author would like to thank Professors Menahem Kaftory of Technion Israel Institute of Technology, Takaji Fujiwara of Shimane University, and Yuji Oohashi of Ochanomizu Womens University for their valuable X-ray analyses of many host-guest inclusion complexes. 

Matrix Assisted Laser Desorption Ionization. During the development of MS, a lot of studies have been devoted to the use of laser light as an energy source for ionizing molecules. As a result, in the mid 1980s MALDI[5] was introduced and soon applied to the study of large molecules.[18] Koichi Tanaka was jointly awarded the Nobel Prize for Chemistry in 2002 for the study of large biomolecules by MALDI. 

Koichi Tanaka, Fliroko Takenaka and Mino R. Caira, Tetrahedron Asymmetry 2006, 17, 2216. 

Mass spectrometry requires that the material being studied be converted into a vapor. Great strides have been taken in recent years to address this problem, especially in enticing large, thermally fragile (bio)molecules into the vapor state. Matrix assisted laser ionization-desorption (MALDI) and electrospray ionization (ESI) are two current forefront methods that accomplish this task. Even components of bacteria and intact viruses are being examined with these approaches. John B. Fenn and Koichi Tanaka shared in the award of a Nobel Prize in 2002 for their respective contributions to development of electrospray ionization and soft laser desorption. 

The year 2002 was an extraordinary year for liquid chromatography-mass spectrometry (LC/MS) practitioners. On October 9, 2002, the Royal Swedish Academy of Sciences annonnced their decision to award the Nobel Prize in Chemistry to John B. Fenn, Koichi Tanaka, and Kurt Wiithrich for their development of analytical methods for the identification and structnral analysis of biological macromolecnles. Fenn and Tanaka shared the prize for developing electrospray and soft-laser desorption, respectively. These soft-ionization techniqnes allow macromolecules to be ionized withont fragmentation. 

Prof. Dr. Koichi Tanaka Department of Applied Chemistry Faculty of Engineering Ehime University Matsuyama, Ehime, 790-8577 Japan... 

Waste prevention and environmental protection are major requirements in an overcrowded world of increasing demands. Synthetic chemistry continues to develop various techniques for obtaining better products with less environmental impact. One of the more promising approaches is solvent-free organic synthesis this book of Koichi Tanaka collects recent examples in this field in a concise way so that their performance and merits can be easily judged. This endeavor is very welcome, as most recent syntheses and educational textbooks largely neglect solvent-free techniques. 

Koichi Tanaka 2002, Chemistry Development of matrix-assisted laser desorption ionization (MALDI)... 

Fumio Toda, Koichi Tanaka, and Hisakazu Miyamoto... 

The Laser Desorption Ionization (LDI) was investigated by Franz Hillenkamp and Michael Karas [2, 3], LDI involved sample bombardment with short and intense pulses from a laser light to effect both desorption and ionization of the analyte molecules. It has become a soft desorption ionization method for mass spectrometric analyses of biological macromolecules and small molecular compounds. The MALDI technique was improved by Koichi Tanaka. 

So, when Miiller and Bednorz s report came out in Zeitschrift fur Physik, Japanese physicists not only saw the obscure German journal, but read it very carefully. At first, there was a touch of skepticism, but just a touch. One specialist in superconductors, Koichi Kitazawa, a member of Shoji Tanaka s team at Tokyo University, was not immediately impressed he tossed it off to a graduate student in physics who had asked for permission to repeat the IBM scientists experiment, as one account of the incident had it, and make a joke of it. By November 1986, the Japanese weren t laughing they had done the Meissner test, and the ceramic responded magnetically, confirmation that the Miiller-Bednorz discovery was no fluke. 

John B. Fenn, Koichi Tanaka For their development of soft desorption ionization methods for mass spec-trometric analyses of biological macromolecules. ... 

All MS techniques require an ionization step in which an ion is produced from a neutral atom or molecule. In fact development of versatile ionization techniques has led to MS being the excellent analytical tool it is today. In 2002 the Nobel prize was shared by John Fenn and Koichi Tanaka for their development of electrospray and laser desorp-tion ionization, respectively. 

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