Synergies synergy potentials

With the growth and synergy potential offered by major M As now largely exhausted, the industry once again needs to look for new ways to generate profitable growth. 

Determining the Synergy Potentials that are Directly Business-related... 

As a rule, the business-related synergy potential can be identified using a simplified business system focusing on four areas. 

Top management should also attempt to quantify this additional potential in the top-down and bottom-up process, even though it is usually much less obvious than the short-term synergy potential. Cross-functional teams, external benchmarking comparisons, and the systematic revisiting of the strategic plans of both companies are typical tools for this task. 

Potentiation is similar to synergy in that the combination of two chemicals has much greater toxicity than expected. However in this case only one of the chemicals is toxic the non-toxic chemical simply increases the effects of the other. This means that although exposure to an individual chemical is at a safe level, exposure to several chemicals, each at a safe level, may, because of synergy or potentiation, become a risk This has certainly been suggested for chemicals known as endocrine disrupters (see pp. 131-6). 

While it is difficult for the outsider to estimate the full extent of these synergies, potential partners should at least be able to assess their likely order of magnitude. If more than half of the capacity of the partners is located in the same country, they can probably achieve substantial operating synergies. If more than half of it is located in adjacent countries, potential synergies are likely to be smal-... 

Synergy or Potentiation is where the combination of two drugs has an effect that is greater than simply additive. The contours of the isobologram are concave toward the origin of the plot (Figure 20.3). In most cases, an effect with this... 

Sometimes the additive effects are solely toxic (e.g. additive ototoxicity, nephrotoxicity, bone marrow depression, QT interval prolongation). Examples of these reactions are listed in Table 1.7 , (see below). It is common to use the terms additive , summation , synergy or potentiation to describe what happens if two or more drugs behave like this. These words have precise pharmacological definitions but they are often used rather loosely as synonyms because in practice it is often very difficult to know the extent of the increased activity, that is to say whether the effects are greater or smaller than the sum of the individual effects. 

Distributed and decentrarized manufacturing involves the problem of locally optimized and isolated applications as well as incompatibilities of process and system. To ensure synergy potentials and stabilize the productivity of the distributed assembly plants, an intensive communication and data... 

The 6-methoxymethylene penicillanic acid [93040-42-7] (31, R = CH OCH (2)-isomer, R" = R " = 3) designed to mimic the amino acrylate species found usiag clavulanic acid and sulbactam. Upon the reaction of this compound with the enzyme, the potential exists for further Michael addition to inactivate the enzyme. The compound is indeed a -lactamase inhibitor but no synergy data have been reported. The related imine stmcture... 

Once you have identified all the PSM and ESH programs and elements within your organization, you can develop a chart that shows the potential synergies with your Quality Management program. One axis of this table will be the programs and elements you identified and listed in Exhibit 2-7. The other axis will be the requirements of your Quality Management system. 

Thus, in order to fully realize the potential of catalytic technologies not only will this require technical innovation in multi-disciplinary teams but also the appropriate organizational structures which maximize the synergies between academic and industrial research. The countries which recognize this potential and provide the... 

Subsequent to awarding the contract for the two chlor-alkali plants to Kvaerner Chemetics, Orica contracted with Kvaerner Process Australia to provide services for the chlor-paraffin plant and Outside Battery Limits activities associated with the new Melbourne site, as this would bring synergies to the total project as well as potential cost savings. 

Contact potential difference measurements, os-cillatoiy reactions, 39 85 Contact synergy model, 40 183 Contaminant distribution... 

In particular, the discovery of a fourth HR (H4) and its expression on numerous immune and inflammatory cells has prompted a re-evalu-ation of the actions of histamine, suggesting a new potential for H4-receptor antagonists and a possible synergy between Hj- and H4-receptor antagonists in targeting various inflammatory conditions [98]. 

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