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Successfully Executing Projects

The revamp (or erection of a new unit) requires successful execution of each phase of the project ... [Pg.206]

Combinatorial chemistry and HT E are powerful tools in the hands of a scient ist, as they are a source for meaningful consistent records of data that would be hard to obtain via conventional methods within a decent timeframe. This blessing of fast data acquisition can turn into a curse if the experimentalist does not take precautions to carefully plan the experiments ahead and the means of handling the data and analyzing them afterwards. The two essential elements that ensure a successful execution of ambitious projects on a rational and efficient basis are, therefore, tools that enable the scientist to carefully plan experiments and get the most out of the minimum number of experiments in combination with the possibility of fast and reliable data retrieval from databases. Therefore, experimental planning and data management are complementary skillsets for the pre- and post experimental stages. [Pg.376]

The initial conceptualization of the agelastatin A problem took on the form shown below (Scheme 5).17 The key transform in this sequence features intramolecular addition of an amide-derived anion to a tethered alkynyliodonium salt within 33. The alkylidenecarbene generated from this nucleophilic addition, 32, then has a choice of two diastereotopic C-H bonds (Ha or Hb) for 1,5 insertion. Reaction with Ha would provide an advanced intermediate 31 en route to the target 28. Successful execution of this plan would extend alkynyliodonium salt chemistry in three new directions (1) use of an amine derivative as a nucleophile, (2) intramolecularity in the nucleophile addition step, and (3) diastereoselectivity upon alkylidenecarbene C-H insertion. At the initiation of this project, a lack of precedent on any of these topics suggested that focused scouting experiments to assess feasibility would be prudent before beginning work towards the natural product itself. [Pg.140]

Key elements that must be successfully executed on computer implementation projects... [Pg.8]

Validation guidelines must comply with all formal procedural controls established by the company/organization. They are internal documents providing detailed procedures, activities and sample products necessary to successfully execute a computer systems or related project. [Pg.30]

As the leader of the Owner s project team, the Venture Manager is ultimately responsible for the successful execution of the right project. [Pg.16]

The key elements required to successfully execute computer system validation projects are as follows ... [Pg.707]

The link between quality planning and quality improvement is execution. The continuous improvement cycle (Fig. 5) starts with benchmarking and internal assessment to arrive at a gap analysis. From the gap analysis an action plan with assigned leadership, resources, timelines, and metrics is developed. From this quality plan, the plant s human resources must successfully execute the plan for improvement to occur. It is the leadership s responsibility to assure that the plan is do-able, appropriate and adequate resources are assigned, and that the culture of the plant supports change. This starts with the project leaders who must have not only the technical skills, but also the project... [Pg.3079]

Phase 1. Coordination. CELRE coordination with MPCA, United States Environmental Protection Agency (USEPA) Region V, ERDC the technology vendors (EPI and ecp), the NRRI, Harrison Marine Electronics, and others as appropriate was essential for the successful execution of all aspects of the project, from permitting through sampling and analysis. [Pg.673]

This section presents key elements for execution of a successful revamp project. A typical revamp project has five stages pre-feasibility, conceptual design, FEED, EPC and start-up. A complete revamp project execution sequence is shown in Figure 2.2. Key project resources required, cost estimation methods, their accuracy and deliverables at every project stage... [Pg.35]

Taken as a whole, the proposed synthetic route amounts to a retro-synthetic blueprint of extraordinary symmetry and appeal with two different hetero-Diels—Alder reactions comprising the essence of the strategy. Without question, achieving this total synthesis would be predicated on successful execution of each step in a tandem manner, a matter of some consequence as none of the proposed transformations had ever been demonstrated in non-monomeric contexts. For instance, the numerous intermediates of the assumed mechanism for the Komfeld reductive ring contraction conversion (vide infra) could provide ample opportunity for undesired side reactions in the projected isochrysohermidin synthesis. Thus, con-... [Pg.24]

This is only an apparent paradox. Economic performance is not the full measure of success. These projects are planned and executed for a symbolic value that may well exceed their nominal fiscal value. [Pg.16]

After award of a contract for a reclamation work, the preparation works begin. Preparation is the key to a successful execution of the project and is often... [Pg.116]

In this phase of the toller selection process, we assume the long list became a short list and now one or more candidate tollers from the short list will be given an opportunity to prepare a commercial bid. This by no means indicates the short listed tollers are perfect. There may be deficiencies that need to be corrected in concert with the client. With proper effort, one will be successful and be engaged for the toll. Sometimes it is appropriate to decide on a backup toller, as complications can develop that prevent the primary candidate from executing the project as originally planned, due to an incident in their plant, departure of key personnel, or unexpected production demands on the toller. [Pg.39]

The factors that favour successful industrial innovation have been memorably analysed by a team at the Science Policy Research Unit at Sussex University, in England (Rothwell et al. 1974). In this project (named SAPPHO) 43 pairs of attempted similar innovations one successful in each pair, one a commercial failure - were critically compared, in order to derive valid generalisations. One conclusion was The responsible individuals (i.e., technical innovator, business innovator, chief executive, and - especially - product champion) in the successful attempts are usually more senior and have greater authority than their counterparts who fail . [Pg.381]

Successful installation, or roll-out, of your PSM systems requires sound planning and effective execution. No matter how diligent you have been, or how receptive and well-managed your company may be, no system as complex as PSM can work perfectly the first time. As every project manager knows, it s impossible to anticipate every outcome or contingency—especially when human behavior is involved. Pilot testing a new system provides the opportunity to identify weaknesses under controlled conditions this in turn enables you to fix problems before the system becomes fully operational. Once these problems are corrected, the pilot test produces a template for installation that can be replicated elsewhere. [Pg.147]

A description of how large academic laboratories are administered, illustrating how different management styles can be successful, has appeared in the literature.114 There is great diversity in laboratory operations in large laboratories, but clearly contact between those who plan the projects, those who have high skills in project operations, and those who execute the more... [Pg.42]


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Execution

Project execution

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