Spontaneous abortion causes

Lead is known to cause reproductive and developmental toxicity. Decreased sperm counts and abnormal sperm development have been reported in male workers heavily exposed to lead. Increased incidences of spontaneous abortion have been reported in female lead workers as well as in the wives of male lead workers (13). Lead crosses the placenta and has been found to cause irreversible neurologic impairment to the fetus at maternal blood levels as... 

This drug may cause spontaneous abortion. Women of childbearing age must use a reliable contraceptive If pregnancy is suspected, discontinue use of tiie drug and notify the primary health care provider. Report severe menstrual pain, bleeding, or spotting. 

When the newborn population Is examined It Is found that between 2 and 4% of Individuals, depending on how the figures are calculated, have some type of birth defect which Is considered to be genetic In origin (8,9) The term "birth defect" Is used In a general sense and encompasses all types of structural, metabolic, and other abnormalities which derive from genetic or other prenatal causes. The birth defects detected postnatally represent only a small fraction of the totality of abnormalities which result from genetic aberrations, but most of the latter result In early spontaneous abortions... 

Brucella abortus is a cause of spontaneous abortion in cattle. In humans it causes undulant fever, i.e. a fever in which temperature undulates with time. Brucella melitensis infects goats it causes an undulant fever called Malta fever, which is common in people living in Mediterranean countries where large flocks of goats are kept. 

Hydrogen sulfide has not been shown to cause cancer in humans, and its possible ability to cause cancer in animals has not been studied thoroughly. Hydrogen sulfide has not been classified for its ability to cause or not cause cancer. There is some evidence that exposure to hydrogen sulfide may lead to an increase in spontaneous abortions in humans. However, the studies where this effect was reported are complicated by exposures to other chemicals and a lack of information on the amount of exposure to hydrogen sulfide. 

Vadillo OF, Avila VMA, Guerrero HC, Arechavaleta VF, Montoya BJ. Apoptosis in trophoblast of patients with recurrent spontaneous abortion of unidentified cause. Ginecol Obstet Mex 2000 68 122-131. 

Reproductive effects from lead exposure have been documented in animals and human beings of both sexes. High occupational exposure levels in pregnant women have been associated with increased incidences of spontaneous abortions, miscarriages, and stillbirths. Some studies also seem to indicate that prenatal exposure to lower levels of lead may increase the risk of preterm delivery and reduced birth weight. Lead penetrates the placental barrier and has caused congenital abnormalities in animals. There is no conclusive evidence, however, that low-level lead exposure leads to an increased incidence of... 

The cause of abortion is generally a defective ovum, which progestational agents could not be expected to influence. In addition, progestational agents have uterine relaxant properties that may cause a delay in spontaneous abortion when given to patients with fertilized defective ova. 

Abel, Ernest L. Fetal Alcohol Abuse Syndrome. New York Plenum Press, 1998. Describes the causes and consequences of fetal alcohol syndrome, including pregnancy-related problems (such as spontaneous abortion), birth defects, and neurological abnormalities. There is also discussion of how to diagnose the condition and how to estimate its prevalence. 

Prolonged contact between toluene and human skin may cause nonallergic contact dermatitis. Human exposure to toluene also causes nervous system symptoms and signs and excessive exposure may cause adverse effects on the kidney and liver. Adverse effects on the nervous system have been observed in experimental animals. In studies of spontaneous abortion, perinatal mortality and congenital malformations in humans, the numbers of cases were small and the mothers had also been exposed to other substances. Embryotoxicity that generally occurs concurrently with maternal toxicity has been seen in some studies in mice and rats but not rabbits (lARC, 1989a). 

Alee Vera (Aloe barbadensis) Uses Topically for bums, skin irritation, sunburn, wounds internally used for constipation, amenorrhea, asthma, colds Actions Multiple chemical components aloinosides inhibit H20 electrolyte reabsorption irritates colon which T peristalsis propulsion wound healing d/t i production of thromboxane A2, inhibiting bradykinin, histamine Available forms Apply gel topically 3-5/d PRN caps 100-200 mg PO hs Contra Do not use if PRG, lactating, or children <12 y Notes/SE Abd cramping, D, edema, hematuria, hypokalemia, muscle weakness, dermatitis Interactions w/ internal use T K+ loss W/ BB, corticosteroids, diuretics, licorice T effects OF antiarrhythmics, corticosteroids, digoxin, diuretics, hyperglycemias, jimsonweed EMS Assess for dehydration, electrolyte imbalance (hypokalemia), abd distress w/ internal use stimulates uterine contractions may cause spontaneous abortion... 

Developmental Effects. Based on the existing information, it is not known whether silver causes developmental toxicity in humans. No studies were found concerning developmental effects in humans after exposure to silver. However, a human study by Robkin et al. (1973) did investigate the possibility of a relationship between the concentration of this heavy metal in the tissue of fetuses and the occurrence of developmental abnormalities. These authors reported that the concentration of silver in the fetal liver of 12 anencephalic human fetuses was higher (0.75 0.15 mg/kg) than the values from 12 fetuses obtained either through therapeutic abortions (0.23 0.05 mg/kg), or in 14 spontaneously aborted fetuses (0.21 0.05 mg/kg). The concentration in 9 premature infants was 0.68 0.22 mg/kg. The authors could not determine if the higher concentrations of silver in anencephalic fetuses were associated with the malformation, or with fetal age. 

The effects of methamphetamine on unborn babies in pregnant women can be significant. Methamphetamine has been known to cause spontaneous abortions or severe birth defects. Babies born to mothers who use methamphetamine often have low birth weights, tremors, excessive crying spells, along with behavioral disorders that can last well into late childhood. 

Nitrous oxide abuse may also lead to spontaneous abortion in pregnant women. It also interferes with DNA synthesis. For these reasons, it is not given to pregnant women, particularly in the first two trimesters. Heavy, ongoing nitrous oxide exposure during pregnancy has caused birth defects in animal studies, as well. 

More than one-third of spontaneous abortions are caused by chromosomal and genomic mutations. Chromosomal mutations produce their effect mainly by predisposing the organism to transmit unbalanced combinations of chromosomes. 

Chromosomal abnormalities also are a common cause of abortion. It is estimated that at least 50% of spontaneous abortions are caused by chromosomal aberrations. Nevertheless, less weight is given to these, because their social impact is much less than that of postnatal death or severe disease. 

Thankfully there was generally a wise-woman in every community who had the skill to perform an abortion, or to provide advice about natural chemicals that were known to cause a spontaneous abortion,... 

In animals, THC can cause spontaneous abortion, low birth weight, and physical deformities (32). However, these were only seen after treatment with extremely high doses of THC (50-150 times higher than human doses), and only in rodents and not in monkeys. 

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