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Sodium thiosalicylate

Oral 325, 650 mg enteric-coated tablets Sodium thiosalicylate (generic, Rexolate)... [Pg.819]

Sodium Thiosalicylate. Sodium thiosalicylate (Rexo-late) is the sulfur or thio analogue of sodium salicylate. It is more soluble and better absorbed, thus allowing lower dosages. It is recommended for gtxit. rheumatic fever, and muscular pains in doses of 100 to ISO mg every 3 to 6 hours for 2 days, and then 100 mg once or twice daily. It is available only for injection. [Pg.755]

Synonyms Aspirin Acetylsalicylic acid Ace-taminosalol Aluminum aspirin Bismuth subsalicylate Choline salicylate Magnesium salicylate Methyl salicylate Phenyl salicylate Potassium salicylate Salsate Salicylsalicylic acid Sodium salicylate Sodium thiosalicylate Triethanolamine salicylate Willow extract... [Pg.2345]

SODIUM THIOSALICYLATE (Arthrolate, Asproject, Rexolate, Thiocyl,... [Pg.649]

Sodium thiosalicylate, a nonnarcotic analgesic, antipyretic, and antiinflammatory agent, is indicated for mild pain, in the treatment of rheumatic fever, or acute gouty arthritis (see also Table 3). [Pg.649]

Other salicylates available for systemic use include salsalate (salicylsalicylic acid disalcid, others), which is hydrolyzed to salicylic acid during and after absorption, sodium thiosalicylate (injection REXOLATe), choline salicylate (oral liquid arthropan), and magnesium salicylate (tablets magan, momemtum, others). A combination of choline and magnesium salicylates (choline magnesium, trisahcylate, triusate, others) also is available. [Pg.443]

Sodium thiosalicylate (Solate) is administered intramuscularly (IM) for the treatment of rheumatic fever, muscular pain, and acute gout. [Pg.1454]

Reactions. Thiosalicylic acids reacts with ethylmercuric chloride in alcohol and in the presence of sodium hydroxide to yield sodium ethyhnercurithiosalicylate [54-64-8] (thimerosal Merthiolate, EH Lilly and Company) (63) (eq. 12). [Pg.293]

The moist cake is mixed with 27 g. of zinc dust and 300 cc. of glacial acetic acid in a x-1. round-bottom flask, and the mixture is refluxed vigorously for about four hours (Note 4). When the reduction is complete, the mixture is cooled and filtered with suction. The filter cake is washed once with water and then transferred to a i-l. beaker. The cake is suspended in 200 cc. of water and the suspension is heated to boiling. The hot solution is made strongly alkaline by the addition of about 40 cc. of 33 per cent aqueous sodium hydroxide solution. The alkaline solution is boiled for about twenty minutes to insure complete extraction of the product from the filter cake, filtered from the insoluble material (Note 5) and the thiosalicylic acid is then precipitated by the addition of sufficient concentrated hydrochloric acid to make the solution acid to Congo red paper. The product is filtered with suction, washed once with water and dried in an oven at 100-110°. The yield of a product which melts at 162-163° is 110-130 g. (71-85 per cent of the theoretical amount based on the anthranilic add). [Pg.77]

Of the several methods described for the production of thiosalicylic acid, only the following are of preparative interest heating of o-halogenated benzoic acids with an alkaline hydrosulfide at i50-200° in the presence of copper or copper salts,1 5 or by substitution of sodium sulfide at 200° 2 by reduction of dithiosalicylic add with glucose,3 or metals 4,5 in alkaline solution. The dithiosalicylic add is prepared by treating diazo-tized anthranilic acid with sodium disulfide in alkaline solution.4... [Pg.79]

Methyl mercuric chloride Sodium hydroxide Thiosalicylic acid... [Pg.3205]

To a solution or suspension in alcohol of 0.1 mole of methyl mercuric chloride is added 0.1 mole of sodium hydroxide in water and 0.1 mole of thiosalicylic acid in ethanol. The product is poured into water, whereupon the methyl mercurithiosalicylic acid is precipitated, since it is insoluble in water. This precipitate can be collected on a filter, and washed well with water to remove all the alcohol, salts, and free inorganic acids. The washed precipitate may then be dissolved in a water solution of sodium hydroxide, or, better, in a water solution of sodium bicarbonate. This produces the water-soluble salt of the methyl mercurithiosalicylic acid. [Pg.3205]

Thimerosal is prepared by the interaction of ethylmercuric chloride, or hydroxide, with thiosalicylic acid and sodium hydroxide, in ethanol (95%). [Pg.778]

Synonyms Sodium ethylmercury thiosalicylate Merthiolate Thimerosal Chemical Formula CgHgHgNaOaS Chemical Structure ... [Pg.2565]


See other pages where Sodium thiosalicylate is mentioned: [Pg.909]    [Pg.912]    [Pg.414]    [Pg.123]    [Pg.1454]    [Pg.909]    [Pg.912]    [Pg.414]    [Pg.123]    [Pg.1454]    [Pg.395]    [Pg.104]    [Pg.23]    [Pg.227]    [Pg.9]    [Pg.21]    [Pg.22]    [Pg.104]    [Pg.892]    [Pg.104]    [Pg.892]    [Pg.421]    [Pg.433]    [Pg.881]    [Pg.1882]    [Pg.161]    [Pg.22]    [Pg.2565]   
See also in sourсe #XX -- [ Pg.649 ]

See also in sourсe #XX -- [ Pg.443 ]




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