Smoking tobacco cancer caused

A large number of polycyclic aromatic hydrocarbons are known Many have been synthesized m the laboratory and several of the others are products of com bustion Benzo[a]pyrene for example is present m tobacco smoke contaminates food cooked on barbecue grills and collects m the soot of chimneys Benzo[a]pyrene is a carcinogen (a cancer causing substance) It is converted m the liver to an epoxy diol that can induce mutations leading to the uncontrolled growth of certain cells... 

Some fused benzene rings have been implicated as carcinogens (cancer-causing agents). Several of these are found in tobacco smoke. 

A. There are no known health problems from oral Salvia use. However, it is known that smoking tobacco is damaging to your lungs and may cause cancer, emphysema, bronchitis, stroke and cardiovascular disease. These toxic side-effects of tobacco smoking are not due mainly to nicotine but rather to combustion products (tars and carbon monoxide), which are present whenever any type of plant material (e.g. Salvia) is smoked. Common sense will tell you that smoking Salvia, or any material, can be bad for your health. It is not known if Salvia can cause birth defects, but it is prudent to assume that it could. 

TAR/TPM Total particulate matter. An all-purpose term for particle-phase constituents of tobacco smoke, many of which are carcinogenic (cancer-causing) or otherwise toxic. 

The compounds of the particle phase are collectively called tar, or total particulate matter (TPM). Tar is the oily residue left behind when moisture evaporates from burned tobacco. It contains thousands of compounds, including cancer-causing aromatic amines, nitro-samines, and polycyclic aromatic hydrocarbons that are present in both smoking and smokeless tobacco. Other harmful constituents include radioactive lead and polonium as well as arsenic, among others. 

However, researchers on either side of the dose-dependent theory agree that marijuana smoke, like tobacco smoke, does contain cancer-causing substances. These researchers do not believe that one form of smoke is more or less dangerous than the other. They all agree that smokers who use both marijuana... 

The Hiickel rule is strictly applicable only to monocyclic compounds, but the general concept of aromaticity can be extended beyond simple mono-cyclic compounds to include polycyclic aromatic compounds. Naphthalene, with two benzene-like rings fused together, anthracene, 1,2-benzpyrene, and coronene are all well-known compounds. Benzolalpyrene is particularly interesting because it is one of the cancer-causing substances that has been isolated from tobacco smoke,... 

Tobacco-derived nitrosamines are considered to be one of the major cancer-causing agents found in tobacco smoke and tobacco products. This is of importance as up to 90% of human lung cancers can be linked to cigarette smoking. The most potent carcinogen found in tobacco is the nicotine-derived nitrosamine 4-(me-thylnitrosamino)-l-(3-pyridyl)-l-butanone. 

Tobacco and tobacco smoke exposure has been identified with numerous health effects. Each year, almost 450,000 people in the United States and millions worldwide die from tobacco use. Cigarette smoking is associated with cancer of the lung, oral cavity, pharynx, larynx, esophagus, kidney, liver, bladder, stomach, colon, rectum, and some leukemias. Smoking is the cause of at least 30% of all cancers and 87% of lung cancers.I37 38 ... 

There are five to seven kinds of nitrosamines normally present in tobacco smoke condensate. The internal standard is a nitrosamine that does not occur in tobacco or its smoke, but is used to confirm the emergence time and quantify the amounts of the nitrosamines in the samples. The curious effect of the additive is that one of these peaks, corresponding to a particularly toxic cancer-causing nitrosamine called NNK, decreases in size, roughly in proportion to the amount of additive in the cigarette. An increase in the size of a peak corresponding to a less cancerous nitrosamine called NAT is also observed. This is a promising result. Could it be an additive that improves the flavor of the product and makes it less harmful ... 

Hoffmann 1989). The determination of the agent(s) in tobacco smoke responsible for causing cancer has been and continues to be an extremely challenging problem. Most notable for this discussion, however, is that several nicotine-related metabolites are fonned in humans in apparent detoxication processes. Study of these enzymatic processes could reveal why certain people are less susceptible to the harmful effects of nicotine. That is, certain humans may be endowed with the ability to decrease the potential untoward effects of nicotine by an abundance of detoxication processes. Careful study of the enzymes involved in nicotine detoxication could provide valuable clues for designing new catalysts useful in decreasing the... 

Smoking. Lung cancer is the second most common form of cancer and the most common cause of cancer death in the United States (NCI 2008b). Cigarette smoking is associated with an increased risk of various cancers (Table 15.3). Tobacco is estimated to cause one-third of all cancer... 

Cooper et al. published a paper (814) in the 1968 National Cancer Institute monograph Toward a Less Harmful Cigarette (4343) in which they suggested that free radicals in MSS were possible contributors to tobacco smoke carcinogenesis. They summarized research from the previous decade on free radicals in tobacco smoke and discussed the possible role of free radicals as a cause of cancer (814). It should be noted that as early as 1954, Dorn reviewed the published experimental evidence that indicated that the products formed by the combustion of tobacco may cause skin cancer in mice. He stated that compared to other known carcinogens, the combustion products of tobacco smoke are relatively weak. (27A30). 

Other studies conducted by government and other research facilities contend that the only proven long-term effects of marijuana use are all related to risks posed by smoking. Users usually inhale marijuana smoke deeply and hold the smoke in their lungs for at least several seconds. Marijuana smoke contains tar, carbon monoxide, and many complex chemicals, almost all of which are respiratory irritants and potential cancer-causing agents. In fact, according to the lOM report, each inhalation of marijuana smoke contains three to five times more tar and carbon monoxide than an equal amount of tobacco smoke. Therefore, a person who smokes marijuana daily for... 

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