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Sensor synthesis methods

Another example in which literature results were reanalyzed in view of the PSSC concept concerns the development of ligands for the farnesoid X receptor. The farnesoid X receptor is a transcriptional sensor for bile acids, the primary products of cholesterol metabolism, and plays an important role in lipid homeostasis. The farnesoid X receptor was, until recently, an orphan receptor, which means that no specific ligands existed for this receptor. Selective ligands for this receptor have been found in natural product libraries described by Nicolaou et al. The group of Nicolaou developed solid phase synthesis methods to make combinatorial libraries based on a benzopyran core structure. " A 10,000-membered combinatorial library based on the benzopyran core structure was synthesized and screened for activity on the farnesoid X receptor. The first specific ligands for the... [Pg.73]

In this section we examine the factors that influence sensor design and explore some of the sensor fabrication methods that are widely employed in sensor synthesis making a critical comparison between them. [Pg.436]

Major Applications Sensors, detection method for DNA amplification, inhibition of neurode-generative diseases, " RNA hydrolysis," fluorescent probes,primers for nucleic acid sequencing,synthesis of nucleic acids, antimalerial agent"... [Pg.22]

It was also found that the effect of additives on sensor performance is dependent on the synthesis method and postdeposition heat treatments employed during sensor fabrication (Miller et al. 2006). Moreover, it was established that additives do not always enhance sensor performance. For example, Min and Choi (2004) tried to control crystallite growth by introducing Ca as a growth inhibitor into the SnO. The additive decreased the SnO crystallite size as expected but depressed the response of the gas sensor and its long-term stability. This means that, depending on the application, the doping material and its quantity have to be chosen carefully. [Pg.326]

If the mappings T in the sensor equation (6.75) and the actuator equation (6.76) are purely hysteretic they can be modeled by a Prandtl-Ishhnskii operator H, a modified Prandtl-Ishlinskii operator M or a Preisach hysteresis operator R depending on the degree of symmetry of the branching behaviour. The calculation of these hysteresis operators and the corresponding compensators from the measured output-input characteristic requires special computer-aided synthesis procedures which is based on system identification methods. Due to a lack of space, this article cannot further comment on these synthesis methods. However, a detailed description of both the synthesis method and the mathematical basics can be found in the literature [332,341,350-352,356]. [Pg.260]

The formation of open and porous structures with extremely large surface area is of high technological significance, because this structure type is very suitable for electrodes in many electrochemical devices, such as fuel cells, batteries and sensors [1,2], and in catalysis applications [3]. The template-directed synthesis method is most commonly used for the preparation of such electrodes. This method is based on a deposition of desired materials in interstitial spaces of disposable hard template. When interstitial spaces of template are filled by deposited material, the template is removed by combustion or etching, and then the deposited material with the replica structure of the template is obtained [4, 5]. The most often used hard templates are porous polycarbonate membranes [6, 7], anodic alumina membrane [8-10], colloidal crystals [11, 12], echinoid skeletal stractures [13], and polystyrene spheres [14, 15]. [Pg.187]

Through the examples presented above, MIPs appear to be very pronusing novel bioelements. They are more stable and more reproducible than natural antibodies. They can be used in combination with various transducers (electrochemical, optical, itnmunosensors, etc.). The synthesis can be set up so that the MIPs are directly synthesized on the transducer. A large diversity of functional monomers and cross-linking polymers as well as synthesis methods is available. An easy fabrication and characterization of the MIP could give them the potential to be widely used in an industrial fabrication of the sensors. [Pg.532]

Recent developments in polymer chemistry have allowed for the synthesis of a remarkable range of well-defined block copolymers with a high degree of molecular, compositional, and structural homogeneity. These developments are mainly due to the improvement of known polymerization techniques and their combination. Parallel advancements in characterization methods have been critical for the identification of optimum conditions for the synthesis of such materials. The availability of these well-defined block copolymers will facilitate studies in many fields of polymer physics and will provide the opportunity to better explore structure-property relationships which are of fundamental importance for hi-tech applications, such as high temperature separation membranes, drug delivery systems, photonics, multifunctional sensors, nanoreactors, nanopatterning, memory devices etc. [Pg.131]


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See also in sourсe #XX -- [ Pg.12 , Pg.436 ]




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Sensor synthesis methods depositing thin films

Sensor synthesis methods techniques

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