New Ligand Specificities

The application of a rhodium(I) catalyst bearing tunable bidentate phosphine ligands, such as 10, opened the possibility for the development of a new catalytic enantioselective reaction [13c]. In a control experiment, it was noted that the reaction with a catalyst containing a bidentate phosphine ligand, specifically RhCl(CO)(dppe), was significantly decelerated as compared to the reaction with [RhCl(CO)2]2 (Scheme 11.12). 

Radiolabelled cis-flupenthixol can be used as a ligand specific for the dopamine receptor linked to adenylyl cyclase in the rat striatum (64). Its affinity for the dopamine receptor in the anterior pituitary has not been measured. (Previously (65) the two categories of dopamine receptors were designated as a-dopaminergic" and P-dopaminergic. This has led to confusion with the a and p adrenoreceptors. The new designations should prevent further confusion.)... 

Kramer, R. H., Enenstein, J., and Waleh, N. S., Integrin structure and ligand specificity in cell-matrix interactions, in Molecular and Cellular Aspects of Basement Membranes (D. H. Rohrbach and R. Timpl, Eds.), pp. 239-258. Academic Press, New York, 1993. 

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