Scope authorization

A scope or budget authorization, the next level of economic evaluation, requires a more defined process definition, detailed process flow sheets, and prefinal equipment design (discussed in a later section). The information required is usually obtained fiom pilot plant, marketing, and other studies. The scope authorization estimate could cost upwards of 80,000 for a 5 million facility with a probable error exceeding 20%. 

In addition to their practical importance, colloidal suspensions have received much attention from chemists and physicists alike. This is an interesting research area in its own right, and it is an important aspect of what is referred to as soft condensed matter physics. This contribution is written from such a perspective, and although a balanced account is aimed for, it is inevitably biased by the author s research interests. References to the original literature are included, but within the scope of this contribution only a fraction of the vast amount of literature on colloidal suspensions can be mentioned. 

Another useful approach is to attempt to get a broad review of the specification draft by operations, maintenance, and engineering. The specification must have an author who can write the basic document and who later edits the draft into the scope and language of the final specification. Single authorship, with committee review, is preferred over committee authorship. Only in rare instances is vendor participation in the specification authorship really justified, except in partnership relationships. 

Do the lockout/tagout procedures clearly outline the scope, purpose, authorization, rules, and techniques to be utilized for the control of hazardous energy and the means of enforcing compliance [OSHA Reference. 147(c)(4)(ii)]... 

A person s job can be divided into two components actions and decisions. Responsibilities and authority should therefore be described in terms of the actions assigned to an individual to perform and discretion delegated to an individual that is, the decisions they are permitted to take along with the freedom they are permitted to exercise. Each job should therefore have core responsibilities, which provide a degree of predictability, and innovative responsibilities, which in turn provide the individual with scope for development. 

In 1888, Combes described condensation of 2,4-pentadione (acetylacetone) 5 with aniline 1 to provide enamine 6. Subsequent warming in sulfuric acid provided quinoline 7. An excellent study describing scope and limitations of the Combes reaction was published in 1928 by Roberts and Turner. The authors noted that the ease of... 

The authors of this review hope to have demonstrated the versatile and frequently unexpected nature of acetylene and pyrazole reactions—a scope so broad that it cannot fail to suggest potential uses to the reader in almost any heterocyclic field. 

General. The general rules of this Code shall apply to electric wiring and equipment in occupancies within the scope of Articles 511 through 517, except as such rules are modified in those articles. Where unusual conditions exist in a specific occupancy, the authority having jurisdiction shalljudge with respect to the application of specific rules. 

A short dissertation upon almost any extensive subject such as this subject is usually blessed by the reader s understanding that generalizations are not only justifiable but also mandatory in order to cover the scope of the subject. However, a learned treatise of ponderous bulk can be readily exempted from criticism for tedious passages devoted to details in that the authors are attempting to present a full and uncompromised assay of the subject. Somewhere in between lies this... 

With the publication of Vol. 51 we should also like to refer to editorial policy this series publishes invited, critical review articles of new developments in all areas of Polymer Science in English (authors may naturally also include works of their own). The responsible editor, that means the editor who has invited the article, discusses the scope of the review with the author on the basis of a tentative outline which the author is asked to provide. Author and editor are responsible for the scientific quality of the contribution the editor s name appears at the end of it. Manuscripts must be submitted, in content, language and form satisfactory, to Springer-Verlag. Figures and formulas should be reproducible. To meet readers wishes, the publisher adds to each volume a volume index which approximately characterizes the content. 

Copy of the manufacturing authorization referred to in Art. 13(1) of the Directive stating the scope of fhis authorization... 

Outside of the products that come within the scope of Community Authorisations, all other products can only be licensed via application to the Competent Authorities of individual Member States. However, through the use of either decentralised or mutual recognition procedures it is possible to obtain authorisations on the basis of a dossier assessment conducted by a single Member State. 

Summary and conclusions The Inspector(s) should state whether, within the scope of the inspection, the company operates in accordance with the EU GMP Rules provided, where relevant, that appropriate corrective actions are implemented and mention any other item to alert requesting authority. Reference may be made to conclusions recorded in other documents, such as the close-out letter, depending on national procedures. 

Surveillance requests are usually targeted at particular concerns, vhich the FDA vill specify as part of the scope of the surveillance order. The manufacturer must submit a plan to the FDA outlining ho v the surveillance vill be conducted. Once approved, the surveillance plan must be put into effect, usually for not more than 3 years, and any reports agreed as part of the plan must be submitted to the FDA. Surveillance plans are quite similar in concept to the safety studies that may be agreed vith regulatory authorities for drugs. 

Organic chemistry is blessed with a large number of books devoted to a thorough coverage of a specific area. Many of these are essentially very long review articles, differing from ordinary review articles only in size and scope. Some of the books are by a single author, and others have chapters by different authors but all are carefully planned to cover a specific area. Many of these books have been referred to in... 

In 1982 the present author discovered cyclic orbital interactions in acyclic conjugation, and showed that the orbital phase continuity controls acyclic systems as well as the cyclic systems [23]. The orbital phase theory has thus far expanded and is still expanding the scope of its applications. Among some typical examples are included relative stabilities of cross vs linear polyenes and conjugated diradicals in the singlet and triplet states, spin preference of diradicals, regioselectivities, conformational stabilities, acute coordination angle in metal complexes, and so on. 

Pyridine-based N-containing ligands have been tested in order to extend the scope of the copper-catalyzed cyclopropanation reaction of olefins. Chelucci et al. [33] have carefully examined and reviewed [34] the efficiency of a number of chiral pyridine derivatives as bidentate Hgands (mainly 2,2 -bipyridines, 2,2 6, 2 -terpyridines, phenanthrolines and aminopyridine) in the copper-catalyzed cyclopropanation of styrene by ethyl diazoacetate. The corresponding copper complexes proved to be only moderately active and enantios-elective (ee up to 32% for a C2-symmetric bipyridine). The same authors prepared other chiral ligands with nitrogen donors such as 2,2 -bipyridines 21, 5,6-dihydro-1,10-phenanthrolines 22, and 1,10-phenanthrolines 23 (see Scheme 14) [35]. 

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