Research data, availability

Table I provides general information on the identified allelopathic weeds and the crops they affect. More detailed information on two of these weeds, johnsongrass and purple nutsedge, will be presented to show the tenuous nature of the evidence for allelopathy. These two species are undoubtedly allelopathic, at least under certain conditions. Rigorous proof that allelopathy is the agent responsible for even a specific portion of the interference exerted by them is not easily attained, however, even though these are the weeds with the best research data available of those weeds that occur in the Mid-South.

The limited research data available also suggests a role for antidepressants in the treatment of patients with STPD. We recommend using a SSRl/SNRl antidepressant that conld theoretically address both depressive symptoms and those of the personality disorder. In our experience, schizotypal patients can nsnally tolerate a more conventional dose increase schedule than can patients with PPD. 

In the following section, I have attempted to formulate a recommendation for an extended test scheme based on the existing standards and on the rare research data available. 

The applicability of mesoscale techniques to systems difficult to describe in any other manner makes it likely that these simulations will continue to be used. At the present time, there is very little performance data available for these simulations. Researchers are advised to carefully consider the fundamental assumptions of these techniques and validate the results as much as possible. 

The interpretation of the experimental data obtained by researchers in the field is much to be desired. There is great tendency to invoke the great escape-route termed steric hindrance whenever results are acquired that do not quite fit any theory, and there is a great reluctance to admit that there are many data that do not fit the present theories. Furthermore, the shortage of accurate and appropriate data for most sensory work must cast doubt on some of the conclusions reached. There are very few quantitative data available from which to refine the arguments and hypotheses. 

The ECO method was developed to aid environmental impact and cost optimisation of chemical synthesis pathways or processes suitable for the research and development (R D) stage. In order to represent terms of ecological as well as economic sustainability, three objective functions which incorporate (i) energy demand (EF), (ii) risks concerning human health and the environment (EHF) and (iii) costs (CE), were defined. Their calculation follows the life cycle approach and is based on the data available already in R D. Because the application of a comprehensive LCA is both, too complex and based on data which are partially not available at the R D stage, the determination of the three objective functions is based on the SLCA approach extended by economic issues. The key objectives are introduced below. 

This work was partially supported by an International Research Scholarship from the Howard Hughes Medical Institute (to G.B.) and by a collaborative research grant from Pfizer Central Research (to G.B.). Digital Equipment Corporation generously loaned the Alpha workstations used for the calculations. Riccardo Destro kindly made the l-alanine diffraction data available to us. Thanks are also due to Mark Spackman, Carlo Gatti and Eric de La Fortelle for useful discussions. 

Eastern Research Group, Final Analysis of Data Available for Development of COD Limitations, prepared for U.S. EPA, August 25, 1997. 

Make the raw data available, so that independent researchers and agencies can do their own analyses of them. 

Fighetti, C. F., and D. G. Reddy, 1982, Parametric Study of CHF Data, Vol. 1 Compilation of Rod Bundle CHF Data Available at the Columbia University Heat Transfer Research Facility and 1983, Parametric Study of CHF Data, Vol 3 CHF Data (1983), EPRI Rep. NP-2609, EPRI, Palo Alto, CA. (5)... 

Certain subgroups of the population may be more susceptible to the toxic effects of lead exposure. These include crawling and house-bound children (<6 years old), pregnant women (and the fetus), the elderly, smokers, alcoholics, and people with genetic diseases affecting heme synthesis, nutritional deficiencies, and neurological or kidney dysfunction. This is not an exhaustive list and reflects only current data available, further research may identify additional susceptible subgroups. 

For protection of domestic cattle, feeds should contain <0.05 mg diflubenzuron/kg FW. Cottonseed may be added to cattle diets provided that diflubenzuron concentrations in the seed do not exceed 0.2 mg/kg FW and that cottonseed composes <17% of the total diet bulk (Gartrell 1981). Diflubenzuron causes biochemical upset, as judged by lowered testosterone levels in chickens and rats (USEPA 1979), altered glutathione 5-transferase activity in mouse liver (which adversely affects the ability to detoxify foreign substances by way of conjugation Young et al. 1986), and disrupted hydroxylamine activity in human infants (USEPA 1979). Additional research seems needed on biochemical alterations induced by diflubenzuron. No diflubenzuron criteria are currently recommended for protection of avian and mammalian wildlife. All data available suggest that wildlife species are about as tolerant to diflubenzuron as are domestic poultry and livestock however, the wildlife database seems inadequate for practicable criteria formulation. 

Wulfenite and minetizit are mainly associated with oxide lead silver ores. Very little to no research data are available on these two minerals. Most recently, research work was carried out on these minerals using natural ore. It has been demonstrated that wulfenite and minetizit can be recovered using sulphidization and modified xanthate. 

The phosphonic acid flotation of cassiterite is similar in many ways to that of arsonic acid. Optimum plant flotation for both collectors is generally considered to be in the pH region 4.5-5.5. The phosphonic acid, like arsonic acid, also has the inability to effectively recover cassiterite coarser than 20 pm. The reason for this is not known, because no research data is available on the flotation properties of plus 20 micron cassiterite particles. 

Due to this faet, data analysis was confronted with the problem that only research material documented in English and German could be double-checked by the authors of this report. The reviews of material written in other languages represent the individual focus of the contracted expert. Data quality delivered is correlated with both data availability and expert knowledge. A comprehensive literature review in international scientific databases was part of each expert survey. 

Data available on CO2 primarily deals with gross emission calculations on commodities and on a per hectare scale, whereas no research results can be presented on CO2 net balances in agriculture. 

In summary, there are five types of analysis that can be used to assess the incremental cost-effectiveness of a drug or service. The type performed is generally predicated by the therapeutic area being evaluated, the research question being addressed and the clinical data available. For example, whereas a CBA (which converts clinical effect into monetary terms) may not be considered (for ethical reasons) to be the best choice for oncology or HIV-related evaluations, a CUA (which takes into account both quality of life and survival duration) may be considered appropriate. 

---