Receptor-dependent

Carta M, Ariwodola OJ, Weiner J L, et al Alcohol potently inhibits the kainate receptor-dependent excitatory drive of hippocampal interneurons. Proc Natl Acad Sci U SA 100 6813-6818, 2003... 

Sanzgiii RP, Araque A, Haydon PG (1999) Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells. J Neurobiol 41 ... 

There are several major classes of Ca channels (1) receptor-operated Ca channels in plasma membranes (2) ligand-gated Ca " channels in intracellular membranes and (3) voltage-dependent Ca channels that are usually found in plasma membranes or the invaginations of the plasma membrane that are known as transverse tubule membranes. Receptor-dependent or receptor-operated Ca channels (ROCCs) are primarily opened in response to activation of their associated receptors and, by definition, exhibit a certain amount of selectivity for Ca " over other cations. Several potentially different types of ROCCs have been characterized including ATP-sensitive channels in smooth muscle [1], mitogen and IP3-sensitive... 

L-type Ca channels are primarily regulated by voltage and are thus opened and closed in response to changes in membrane potential, but in addition, they are regulated by receptor-dependent processes involving protein phosphorylation and G-proteins (Fig. 2). Many lines of evidence support the hypothesis that Ca channels are regulated by phosphorylation by several protein kinases, in particular by... 

Musser B, Mudumbl RV, Liu J, Olson RD, Vestal RE. Adenosine Ai receptor-dependent and -independent effects of the allosteric enhancer PD 81,723. J Pharmacol Exp Ther 1999 288 446 454. 

When chemicals are released in the environment, their hazard potential to human or ecological receptors depends upon the extent of contact between the receptors and the chemical. This exposure level is not only influenced by where, when and how much of the chemical is released, but also on its movement and changes in air, water, soil or biota relative to the locations of the receptors. Risk is defined as the probability of some adverse consequence in the health context, or as the probability times the extent of the consequence in the technology context. In this paper we shall examine and discuss how mathematical models are used to generate estimates of risk when more than one of the environmental media must be considered in tracing pathways connecting sources with receptors. The principal objective here is to place in perspective the... 

Alanko, L Laitinen, J. T., Stenberg, D. Porkka-Heiskanen, T. (2004). Adenosine Al receptor-dependent G-protein activity in the rat brain during prolonged wakefulness. Neuroreport 15 (13), 2133-7. 

Hitri A., Little K., Ellinwood D. Effect of cocaine on dopamine transporter receptors depends on routes of chronic cocaine administration. Neuropsychopharmacology. 14 205, 1996. 

Norris J, Fan D, Aleman C et al. Identification of a new subclass of Alu DNA repeats which can function as estrogen receptor-dependent transcriptional enhancers. J Biol Chem 1995 270[39] 22777-22782. 

R)- and (3 S)-Cyclocymopol monomethyl ether show agonistic or antagonistic effects on the human progesterone receptor, depending on which enantiomer is used... 

Hamilton, S. E.. Loose, M. D., Qi, M. etal. Disruption of the mj receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proc. Natl Acad. Sci. U.S.A. 94 13311-13316,1997. 

Tsien, I. Z., Huerta, P. T. and Tonegawa, S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87 1327-1338,1996. 

G protein y subunits are modified on their C-terminal cysteine residues by isoprenylation [26,27]. There is now strong evidence that this modification plays a key role in anchoring the ysubunit and its associated P subunit to the plasmalemma. The importance of this anchoring is illustrated in Figure 19-2, which shows that the ability of py subunits to direct GRKs to ligand-bound receptors depends on this membrane localization. 

Takasu, M. A., Dalva, M. B., Zigmond, R. E. etal. Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science 295 491-495, 2002. 

Nicoll, R. A. and Malenka, R. C. Expression mechanisms underlying NMDA receptor-dependent long-term potentiation. Ann. NY Acad. Sci. 868 515-525,1999. 

Figtree G, Webb C, Collins P (1999) Raloxifene acutely relaxes rabbit coronary arteries in vitro by an estrogen receptor-dependent and nitric oxide-dependent mechanism. Circulation 100 1095-1101... 

Figtree G, Webb C, Collins P (2000) Tamoxifen acutely relaxes coronary arteries by an endothelium, nitric oxide and estrogen receptor-dependent mechanism. J Pharmacol Exp Ther 295 519-523... 

Cathapermal S, LavigneMC, Leong-Son M,Alibadi T, Ramwell PW (1998) Stereoisomer-specific inhibition of superoxide anion-induced rat aortic smooth-muscle cell proliferation by 17beta-estradiol is estrogen receptor dependent. J Cardiovasc Pharmacol 31 499-505... 

Yeager, M.P. et al., Effect of morphine and P-endorphin on human Fc receptor-dependent and natural killer cell functions, Clin. Immunol. Immunopathol., 62, 336, 1992. 

Camacho, I., et. al., Treatment of mice with 2,3,7,8-tetrachlorodibenzo-p-dioxin leads to aryl hydrocarbon receptor-dependent nuclear translocation of NF-kappa B and expression of Fas ligand in thymic stromal cells and consequent T cell apoptosis, J. Immunol., 175, 90, 2005. 

---