Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Redox-dependent receptors

In general, there are two types of limiting voltammetric behavior observed for redox-dependent receptors.12 First, if there is strong binding in both oxidation... [Pg.5]

It is also possible to affect H-bond strength electrochemically without the H-bonding site being an integral part of the redox couple. Good examples of this are found in the many redox-dependent receptors that utilize metallocenes, primarily ferrocene and cobaltocenium, as the redox couple. These are primarily used in ion receptors, but examples of metallocene receptors that show a significant redox dependence with neutral guests are the cobaltocenium and ferrocene diamides,... [Pg.9]

Ge. Y. Smith, D.K. Development of chemical sensors 126. based on redox-dependent receptors. Preparation and characterization of phenanthrenequiiione-modified electrodes. Anal. Chern. 2000. 72. 1860- 1865. [Pg.519]

Ge Y, Lilienthal RR, Smith DK (1996) Electrochemically-controlled hydrogen bonding. Selective recognition of urea and amide derivatives by simple redox-dependent receptors. J Am Chem Soc 118 3976-3977... [Pg.212]

Ge Y, Miller L, Ouimet T, Smith DK (2000) Electrochemically controlled hydrogen bonding. o-Quinones as simple redox-dependent receptors for arylureas. J Org Chem 65 8831-8838... [Pg.212]

Mochizuki, M., Yano, M., Oda, T., Tateishi, H., Kobayashi, S., Yamamoto, T., Ikeda, Y., Ohkusa, T., Ikemoto, N., and Matsuzaki, M. (2007) Scavenging free radicals by low-dose carvedilol prevents redox-Dependent Ca2+ leak via stabilization of Ryanodine receptor in heart failure. J. Am. Coll. Cardiol. 49,1722-1732. [Pg.1095]

Another important consideration for electrochemical studies is the choice of electrolyte, the ionic compound that is added to maintain electroneutrality and provide a means of charge flow through solution. Because at least one of the oxidation states of the host will be charged, it is possible that ion-ion interactions will play a role in the observed electrochemistry. Indeed, this is useful if the objective is to design a redox-dependent ion receptor, but it can be an interference if the guest is neutral. [Pg.14]

In addition to the arylimides, Smith and coworkers also introduced o-quinones, discussed earlier in this chapter, as another example of a redox-dependent H-bonding receptor for neutral guests (Eq. 1.9).19,47,56 This system differs from the flavins and the imides in that a strong interaction is only observed in the reduced state, making these receptors function as on/off switches. The groups of Rotello and Cooke have also published several papers exploring the redox-dependent H-bonding properties of o-quinones.36,57-59... [Pg.24]

Many of the applications that can be envisioned for electrochemically controlled H-bonding and redox-dependent binding in general will require that at least one of the components be attached to an electrode surface. It is therefore important to determine whether behavior observed in solution can still be observed when the host is anchored to a surface. This was first tested for a redox-dependent H-bonding receptor with the... [Pg.24]

Touyz, R.M., Cruzado, M., Tabet, F., Yao, G., Salomon, S., and Schiffrin, E.L. 2003. Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells role of receptor tyrosine kinase transactivation. Can. J. Physiol. Pharmacol. 81 159-167. [Pg.136]

The well-developed and highly adaptable synthetic chemistry of ferrocene, together with its accessible ferrocene/ ferrocenium (Fc/Fc ) redox couple has led to its abundant use in redox-active receptors. The first organometallic cation receptors to be studied were the ferrocene-modified crown ethers of Saji 1 and Beer 2-4. The electron-rich crown ethers provide the cation-binding site—they are potent ionophores for group 1 and 2 metal cations. NMR (in methanol/acetone solution) and solid-state X-ray crystal structure studies demonstrated that 2-4 bind Na, K, and Cs. The binding stoichiometry varies depending on the receptor and cation used. Both Na and form 2 1 cation receptor complexes with 3, as does Na with 2. The ability of ferrocene to swivel around the CpFeCp axis also allows the formation of a 1 1 intramolecular sandwich complex, as seen in 2 Na, 2 K, 2 Cs and 3 K. ... [Pg.466]

Salas VM, Corcoran GB (1997) Calcium-dependent DNA damage and adenosine 3 5 -cyclic monophosphate- independent glycogen phosphorylase activation in an in vitro model of acetaminophen-induced liver injury. Hepatology 25 1432-1438 Salminen WF Jr, Voellmy R, Roberts SM (1998) Effect of N-acetylcysteine on heat shock protein induction by acetaminophen in mouse liver. J Pharmacol Exp Ther 286 519-524 Schiodt FV, Ott P, Christensen E, Bondesen S (2002) The value of plasma acetaminophen half-life in antidote-treated acetaminophen overdosage. Clin Pharmacol Ther 71 221-225 Schnellmann JG, Pumford NR, Kusewitt DF, Bucci TJ, Hinson JA (1999) Deferoxamine delays the development of the hepatotoxicity of acetaminophen in mice. Toxicol Lett 106 79-88 Shen HM, Pervaiz S (2006) TNF receptor superfamily-induced cell death redox-dependent execution. FASEB J 20 1589-1598... [Pg.404]

The electrochemical properties of redox-active substrates are also affected on binding to a receptor molecule. This is the case for the complexation of metal hexacyanides by polyammonium macrocycles where the shift of the redox potential depends on the binding constants and the oxidation or reduction of the substrates leads to pronounced changes in stability (see Chapter 3) [3.21, 3.22]. [Pg.105]


See other pages where Redox-dependent receptors is mentioned: [Pg.17]    [Pg.518]    [Pg.17]    [Pg.518]    [Pg.406]    [Pg.17]    [Pg.4]    [Pg.224]    [Pg.288]    [Pg.779]    [Pg.108]    [Pg.2]    [Pg.4]    [Pg.533]    [Pg.20]    [Pg.36]    [Pg.129]    [Pg.120]    [Pg.39]    [Pg.105]    [Pg.136]    [Pg.2]    [Pg.4]    [Pg.264]    [Pg.105]    [Pg.150]    [Pg.165]    [Pg.128]    [Pg.131]    [Pg.523]    [Pg.20]    [Pg.563]    [Pg.288]    [Pg.144]    [Pg.80]    [Pg.147]    [Pg.41]   
See also in sourсe #XX -- [ Pg.9 , Pg.17 ]




SEARCH



Receptor-dependent

© 2024 chempedia.info