Rainbow trout hepatocytes

Vaillant, C., Monod, G., and Volataire, Y. et al. (1989). Measurement and induction of cytochrome P450 and monooxygenases in a primary culture of rainbow trout hepatocytes. Comptes Redus de L Academic des Sciences 308, 83-88. 

Reader, S., H.B. Steen, and F. Denizeau. 1994. Intracellular calcium and pH alterations induced by tri-n-butyltin chloride in isolated rainbow trout hepatocytes a flow cytometric analysis. Arch. Biochem. Biophys. 312 407-113. 

Gagne, F., S. Trottier, C. Blaise, J. Sproull, and B. Ernst. 1995. Genotoxicity of sediment extracts obtained in the vicinity of a creosote-treated wharf to rainbow trout hepatocytes. Toxicol. Lett. 78 175-182. 

Feng, Q., Boone, A.N. and Vijayan, M.M. (2003) Copper impact on heat shock protein 70 expression and apoptosis in rainbow trout hepatocytes, Comparative Biochemistry and Physiology, Part C 135 (3), 345-355. 

Gagne, F. and Blaise, C. (1998a) Toxicological evaluation of municipal wastewaters to rainbow trout hepatocytes, Toxicology Letters 95 (Supplement 1), 194-194. 

Gagne, F., Blaise, C., van Aggelen, G., Boivin, P., Martel, P., Chong-Kit, R., Jonczyk, E., Marion, M., Kennedy, S.W., Legault, R. and Goudreault, J. (1999a) Intercalibration study in the evaluation of toxicity with rainbow trout hepatocytes, Environmental Toxicology 14 (4), 429-437. 

Gagne, F., Pardos, M., Blaise, C., Turcotte, P., Quemerais, B. and Fouquet, A. (1999b) Toxicity evaluation of organic sediment extracts resolved by size exclusion chromatography using rainbow trout hepatocytes, Chemosphere 39(9), 1545-1570. 

Gagne, F., Ridal, J., Blaise, C. and Brownlee, B. (1999c) Toxicological effects of geosmin and 2-methylisobomeol on rainbow trout hepatocytes, Bulletin of Environmental Contamination and... 

Isomaa, B., Lilius, H., Sandbacka, M. and Holmstrom, T. (1995) The use of freshly isolated rainbow trout hepatocytes and gill epithelial cells in toxicity testing, Toxicology Letters 78 (1), 42-42. 

Rissanen, E., Krumschnabel, G. and Nikinmaa, M. (2003) Dehydroabietic acid, a major component of wood industry effluents, interferes with cellular energetics in rainbow trout hepatocytes, Aquatic... 

Lilius H, Haestbacka T, Isomaa B. A combination of fluorescent probes for evaluation of cytotoxicity and toxic mechanisms in isolated rainbow trout hepatocytes. Toxicol In Vitro 1996 10 341-8. 

Behrens, A., K. Schirmer, N.C. Bols and H. Segner. Polycyclic aromatic hydrocarbons as inducers of cytochrome P4501A enzyme activity in the rainbow trout cell line, RTL-W1, and in primary cultures of rainbow trout hepatocytes. Environ. Toxicol. Chem. 20 632-643, 2001. 

Olsson, P.E., S.J. Hyllner, M. Zafarullah, T. Andersson and L. Gedamu. Differences in metallothionein expression in primary cultures of rainbow trout hepatocytes and the RTH-149 cell line. Biochim. Biophys. Acta 1049 78-82, 1990. 

Hyllner, S.J., T. Andersson, C. Haux and P.-E. Olsson. Cortisol induction of metallothionein in primary cultures of rainbow trout hepatocytes. J. Cell. Physiol. 239 24-28, 1989. 

Risso-de Favemey, C., A. Devaux, M. Lafaurie, J.P. Girard, B. Bailly and R. Rahmani. Cadmium induces apoptosis and genotoxicity in rainbow trout hepatocytes through generation of reactive oxygen species. Aquat. Toxicol. 53 65—76, 2001. 

Boone, A.N. and M.M. Vijayan. Constitutive heat shock protein 70 (HSC70) expression in rainbow trout hepatocytes effect of heat shock and heavy metal exposure. Comp. Biochem. Physiol. 132C 223-233, 2002. 

Devaux, A., M. Pesonen, G. Monod and T. Andersson. Glucocorticoid-mediated potentiation of P450 induction in primary culture of rainbow trout hepatocytes. Biochem. Pharmacol. 43 898-901, 1992. 

Sathiyaa, R. and M.M. Vijayan. Autoregulation of glucocorticoid receptor by cortisol in rainbow trout hepatocytes. Am. J. Physiol. Cell Physiol. 284 C1508-C1515, 2003. 

Maitre, J.L., Y. Valotaire and C. Guguen-Guillouzo. Estradiol-17/3 stimulation of vitellogenin synthesis in primary culture of male rainbow trout hepatocytes. In Vitro Cell. Dev. Biol. 22 337-343, 1986. 

Donohue, M., L.A. Baldwin, D.A. Leonard, P.T. Kostecki and E.J. Calabrese. Effects of hypolipidemic drugs gemfibrozil, ciprofibrate, and clofibric acid on peroxisomal /3-oxidation in primary cultures of rainbow trout hepatocytes. Ecotoxicol. Environ. Saf. 26 127-132, 1993. 

Andersson PE, Blom A, Johannisson A, et al. 1999. Assessment of PCBs and hydroxylated PCBs as potential xenoestrogens In vitro studies based on MCE-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. Arch Environ Contam Toxicol 37 145-150. 

CNCs are becoming an important class of renewable nanomaterials with many applications in different areas, including biomedicine. A number of reviews on the bioapplications of CNCs can be found in the literature. The U.S. Food and Drug Administration (FDA) has listed CNCs as a Generally Regarded As Safe (GRAS) material. The toxicity assessment of CNCs in the microvascular endothelial cells of human brain was conducted and CNCs were found to be non-toxic to cells and therefore could be used as carriers in the targeted delivery of therapeutics. The non-toxicity of CNCs has been confirmed by interactions with rainbow trout hepatocytes and microvascular endothelial cells. The biocompatibility of CNCs has also been verified in a recent study. " ... 

Konemann, H, 1981, Quantitative structure-activity relationship in fish toxicity studies. Toxiocology 19 209-221. Lilius, H., Isomaa, B., Holstrom, T. A comparison of the toxicity of 50 reference chemicals to freshly isolated rainbow trout hepatocytes and Daphnia magna. Aquatic Toxicology 30 47-60. 

JobUng, S.J. and Sumpter, J.P. (1993) Detergent components in sewage effluent are weakly estrogenic to fish an in vitro study using rainbow trout hepatocytes. Aquatic Toxicology 27,361-372. 

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