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Clofibric acid

Lipid regulators gemfibrozil and bezafibrate frequently detected in wastewaters are reported to be eliminated in WWTPs with 46-69% [51] and 36-54% [13]. On the other side, clofibric acid was reported to be refractory pollutant for municipal WWTPs [22]. [Pg.207]

Flaherty B, Paxeus N, Lo Giudice R, Pollio A, Garric J (2003) Ecotoxicological impact of pharmaceuticals found in treated wastewaters study of carbamazepine, clofibric acid, and diclofenac. Ecotoxicol Environ Saf 55 359-370... [Pg.225]

Lake, B.G., Kozlen, S.L., Evans, J.G., Gray, T.J.B., Young, P.J. and Gangolli, S.D. (1987). Effect of prolonged administration of clofibric acid and di-(2-ethylhexyl)phthalate on hepatic enzyme activities and lipid peroxidation in the rat. Toxicology 44, 213-228. [Pg.244]

Continuous bioreactor treatment was developed for the removal of clofibric acid by T. versicolor (data not yet published). That bioreactor was operated in... [Pg.176]

Lipid regulator Clofibric acid I. lacteus Cultures were incubated in 10 mg L-1 Low degradation [3]... [Pg.199]

Clofibric acid LAC from T. versicolor/ MnP from Bjerkandera sp. Flask scale... [Pg.206]

Santos TCR, Rocha JC, Barcelo D (2000) Determination of rice herbicides, their transformation products and clofibric acid using on-line solid-phase extraction followed by liquid chromatography with diode array and atmospheric pressure chemical ionization mass spec-trometric detection. J Chromatogr A 879 3-12... [Pg.273]

Buser, H.-R., Muller, M. D. and Theobald, N. (1998). Occurrence of the pharmaceutical drug clofibric acid and the herbicide mecoprop in various Swiss lakes and in the North Sea, Environ. Sci. Technol., 32, 188-192. [Pg.256]

Y. Kurono, N. Ohta, T. Yotsuyanagj, K. Ikeda, Effects of Drug Binding on the Esterase-Like Activity of Human Serum Albumin. III. Evaluation of the Two Active Sites by Using Clofibric Acid as an Inhibitor , Chem. Pharm. Bull. 1981, 29, 2345 - 2350. [Pg.97]

Another therapeutic class to be briefly discussed is that of the lipid-lowering agents known as fibrates, e.g., clofibrate and fenofibrate (8.5). Here also, the acidic metabolite is the active form clofibrate (an ethyl ester) is rapidly hydrolyzed to clofibric acid by liver carboxylesterases and blood esterases [11], Human metabolic studies of fenofibrate (8.5), the isopropyl ester of fenofibric acid, showed incomplete absorption after oral administration, while hydrolysis of the absorbed fraction was quantitative [12], This was followed by other reactions of biotransformation, mainly glucuronidation of the carboxylic acid group. [Pg.441]

He told us yes, the antilipidemic drug Clofibrate that had clofibric acid (CFA) as the active component. It was given to humans in 2-gram-per-day quantities. [Pg.465]

Andreozzi R, Caprio V, Marotta R, Radovnikovic A (2003) Ozonation and H2O2AJV treatment of clofibric acid in water a kinetic investigation. J Hazard Mater 103 233-246... [Pg.68]

Stan HJ, Heberer T, Linkerhagner M (1994) Occurrence of clofibric acid in the aquatic system - is the use in human medical care the source of the contamination of surface ground and drinking water Vom Wasser 83 57-68... [Pg.69]

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