Phosphonous tris methyl

Plugging solution contains Portland cement, sodium sulphate, potassium ferricyanide and nitrile-tri-methyl-phosphonic acid. Patent SU 1700204-A, 1991. 

P. F. Tsytsymushkin, S. R. Khajmllin, A. P. Tamavskij, Z. N. Kudryashova, and B. V. Mikhajlov. Plugging solution contains Portland cement, sodium sulphate, potassium ferricyanide and nitrile-tri-methyl-phosphonic acid. Patent SU 1700204-A, 1991. 

Some other interesting copolymers having properties of PVC thermal stabUizers, like poly[Af-(a-benzothiazolonylmethyl)methacrylate-co-methyl methacrylate] [45], of flame retardants like a terpolymer of styrene, acrylonitrile and a polymerizable perbrominated phenol [76] or poly[4-methacryloyloxy-2,3,5,6-tetrabromobenzyldi-phenyl phosphonate-co-methyl methacrylate] [104] (93), bioddes, mostly copolymers of monomers containing tris(n-butyl tin) or triphenyl tin moieties and alkyl acrylates, methacrylates, vinyl acetate, acrylonitrile, styrene or A-vinylpyrrolidone [105], e.g. a terpolymer of styrene, MMA and tri(n-butyl tin) itaconate [106] (94),... 

Unsaturated Compounds. — Tri-O-acetyl-D-glucal and the 2-acetoxy-deriva-tive, tri-<9-benzyl-D-glucal, ethyl 4,6-di-0-acetyl-2,3-dideoxy-a-D-ery//zro-hex-2-enopyranoside, 4,6-di-0-acetyI-2,3-dideoxy-a-D-eryf ro-hex-2-eno-pyranosyl dimethyl phosphonate, and methyl 3,4-dideoxy-o -DL-f/2Z eo-hex-3-enopyranoside. ... 

Phosphonic acid, methyl-, dimethyl ester. See Dimethyl methylphosphonate Phosphonic acid, methyl-, (5-ethyl-2-methyl-2-oxido-1,3,2-dioxaphosphorinan-5-yl) methyl methyl ester, p-oxide. See Methylphosphonic acid, (5-ethyl-2-methyl-2-oxido-1,3,2-dioxaphosphorinan-5-yl) methyl methyl ester Phosphonic acid, methyl (5-methyl-2-methyl-1,3,2-dioxaphosphorinan-5-y) ester,P,P -dioxide. See Methylphosphonic acid, bis [(5-ethyl-2-methyl-2-oxido-1,3,2-dioxaphosphorinan-5-yl) methyl] ester Phosphonic acid, [nitriliotris (methylene)] tris-, sodium salt. See Sodium nitrilotris (methylene phosphate)... 

The reaction of 2-deoxy-3,4,6-tri-0-methyl-2-methylamino-D-glucopyranose 149 with methyl(phenyl)phosphonic dichlorides (106a-b) or methylthiophosphonic dichloride in benzene in the presence of triethylamine afforded mixtures of four isomers of the corresponding 1,3,2 oxazaphospholidine-2-ones 150, 151 and... 

Reactions of the same carbonyl ylide intermediate with aldehydes are even more fruitful. The Rh2(OAc)2 catalyzed reaction proceeds at room temperature in the presence of 2 mol% of the catalyst, but the diastereoselectivity is disappointingly low (endo/exo = 49 51, Scheme 11.56). However, when 10 mol% of the cocatalyst Yb(OTf)3 is added, the reaction becomes highly exo-selective (endo/ exo = 3 97) (198). Suga has extended this Lewis acid catalyzed carbonyl ylide cycloaddition reaction to catalyzed asymmetric versions. The chiral cocatalyst employed is ytterbium(III) tris(5)-1,1 -binaphthyl-2,2 -diyl phosphonate, Yb[(S) BNP]3 (10 mol%). In the reaction of methyl o-(diazoacetyl)benzoate with benzyloxyacetaldehyde in the presence of Rh2(OAc)2 (2 mol%) at room temperature with the chiral Yb catalyst, the diastereoselectivity is low (endo/exo = 57 43) and the enantiopurity of the endo-cycloadduct is 52% ee. 

Reaction of 4-aryl-7-iodoperhydropyrido]2,l-c][l,4]oxazin-6-ones (07USA2007/0117839, 08WOP2008/013213) and 7-iodo-6-oxo-4-(3,4,5-tri-fluorophenyl)perhydropyrido[2,l-a]pyrazine-2-carboxylate (07USA2007/ 0117839) with P(OEt)3 at 120 °C for 2 h afforded 7-phosphonic acid diethyl esters. 3-Hydroxy-6-arylperhydropyrido[2,l-c][l,4]oxazin-4-ones first were reacted with triphenylphosphonium bromide in refluxing MeCN, then with 3-methoxy-4-(4-methyl-lH-imidazol-l-yl)benzaldehyde at ambient temperature in the presence of NEt3 to provide (Z)-3- l-[3-methoxy-4-(4-methyl-lH-imidazol-l-yl)phenyl]methylidene] derivatives (07USA2007/ 0117798, 08USA2008 /0207900). 

One embodiment of this general reaction led to a product which was commercially produced for several years by Stauffer as Fyrol 76 (9), a copolycondensation product of dimethyl methyl-phosphonate with bis(2-chloroethyl) vinylphosphonate. The features of Fyrol 76 were high phosphorus content (20%), water solubility, and ability to be polymerized by means of a radical initiator to a crosslinked polymer. A related polycondensation product was developed from tris(2-chloroethyl) phosphate and dimethyl methylphosphonate. By control of the reagents and procedure used for neutralization, these oligomeric products were produced with primary alcohol functional groups (7). 

FePC,6H27, Iron, tetracarbonyl(tri-tert-bu-tylphosphine)-, 25 155 04NPCsH,g, Phosphonic acid, [(, N-di-diethylcarbamoyl)methyl]-, dimethyl ester, 24 101... 

ANTI)]-, ammonium, 26 24 C H2,Cl2PSis, Phosphonous dichloride, tris(trimcthylsilyl)methyl]-, 27 239 C, iH2iiSi), Methane, tris(trimethylsilyl)-, 27 238... 

PCIRuC.wH24. Ruthenium(II), chloro(T -hexamethylbenzene)hydrido(tri-phenylphosphine)-, 26 181 PCIiCiiHn, Phosphonous dichloride, (2,4,6-tri-tm-butylphenyl)-, 27 236 PCIjSiiCioHjT, Phosphonous dichloride, (tris(trimethylsilyl)methyl]-, 27 239 PCoC Hjo, Cobalt, (-ri -cyclopentadienyl)-(n -1, l -( 1,2-ethynediyl)bisbenzene]-(triphenylphosphine)-, 26 192 PCoCjiHm, Cobalt, (ii -cyclopentadienyl)-(2,3-dimethyl-1,4-diphenyl-l, 3-butadiene- 1,4-diy l)(tripheny Iphosphine)-, 26 195... 

Out own research indicates, however, that the reaction product from CH2 0 and P4 consists actually of equal amounts ( 30% each) of hydroxyme-thyl-phosphonic acid (75), bis (hydroxymethyl)phosphinic acid (74), and me-thyl-hydroxymethyl-phosphinic acid (75). Small amounts of methyl-phosphonic acid and tris (hydroxymethyl)phosphine oxide were also detected... 

Nucleoside Polyphosphates. - The preparation of the phosphonate analogues of IpJ and IpsI (130) and (131) has been described. Various methods for the efficient synthesis of these compounds have been examined. The most convenient method employed tris(imidazolido)phosphate and inosine 5 -methyl-enediphosphonate, which had been prepared from 2, 3 -isopropyledeneinosine and methylenebisphosphonic dichloride. ... 

Reducing agents Aluminum hydride. Bis-3-methyl-2-butylborane. n-Butyllithium-Pyridine. Calcium borohydride. Chloroiridic acid. Chromous acetate. Chromous chloride. Chromous sulfate. Copper chromite. Diborane. Diborane-Boron trifluoride. Diborane-Sodium borohydride. Diethyl phosphonate. Diimide. Diisobutylaluminum hydride. Dimethyl sulfide. Hexamethylphosphorous triamide. Iridium tetrachloride. Lead. Lithium alkyla-mines. Lithium aluminum hydride. Lithium aluminum hydride-Aluminum chloride. Lithium-Ammonia. Lithium diisobutylmethylaluminum hydride. Lithium-Diphenyl. Lithium ethylenediamine. Lithium-Hexamethylphosphoric triamide. Lithium hydride. Lithium triethoxyaluminum hydride. Lithium tri-/-butoxyaluminum hydride. Nickel-aluminum alloy. Pyridine-n-Butyllithium. Sodium amalgam. Sodium-Ammonia. Sodium borohydride. Sodium borohydride-BFs, see DDQ. Sodium dihydrobis-(2-methoxyethoxy) aluminate. Sodium hydrosulflte. Sodium telluride. Stannous chloride. Tin-HBr. Tri-n-butyltin hydride. Trimethyl phosphite, see Dinitrogen tetroxide. 

Dioctadecyl 3,5-di-tert-butyl-4-(hydroxybenzyl)phosphonate, 2 == 2,6-Bis(2-octadecyl)-4-methylphenol, 3 = 2,6-Di-tert-butylphenol, 4 = Pentaerythritol tetra-kis[3-[3,5-di-tert-butyl-4-(hydroxyphenyl)Jpropoinate], 5 = 2-tert-Butyl-4,6-dimeth-ylphenol, 6 = 2-tert-Butylphenol, 7 = 2,6-Diisopropylphenol, 8 = 1,3,5-Tris[3,5-di-tert-butyl-4-(hydroxybenzyl)]-2,4,6-trihydroxytriazine, 9 = l,3,5-Trimethyl-2,4,6-tris[3,5-di-tert-butyl-4-(hydroxybenzyl)]benzene, 10 == Methyl 3-[3,5-di-tert-hutyl-4-(hydroxyphenyl)jpropionate, 11 = Monoethyl 3,5-di-tert-butyl-4-(hydroxybenzyl)-vhosphonate, nickel salt, 12 = 2-tert-Butyl-5-methylphenol, 13 = 4,4 -Methylene-bis(2,6-di-tert-butylphenol), 14 = 2-tert-Butyl-6-methylphenol, 15 = Alkylated 2-tert-butyl-5-methylphenol, 16 = 2-tert-Butyl-4-ethylphenol, 17 = Methyl 3-[3-tert-butyl-4-(hydroxyphenyl)]propionate, 18 = 2,4-Di-tert-butylphenol. 

One might expect that a phosphorus reagent having for R an aryl group activated for bimolecular nucleophilic substitution (68) by electron- withdrawing substituents might participate in a Michaelis-Arbuzov reaction. Kamai and Koshkina (159), who prepared a number of chloro-and nitro-substituted derivatives of triphenyl phosphite, found this to be the case for both ortho and para isomers of tris(monochlorophenyl) phosphite, which reacted with alkyl halides to furnish phosphonates. On the other hand, tris(2,4,6-trichlorophenyl) phosphite and tris(2,4-dichlorophenyl) phosphite (155) gave only complexes with methyl iodide however, lower reaction temperatures were employed. 

Phosphonic mono- and di-amides have been widely examined as substrates in the WEH reaction with the considerable success in the use of their carbanions in the non-stereose-lective synthesis of (j5-hydroxyalkyl)phosphonic diamides the result of decreased elec-trophilicity of the phosphorus atom. The fission of such diamides occurs when they are heated in a high-boiling solvent the separated threo and erythro stereoisomers from, for example, benzylic phosphonic diamides undergo decomposition into ( )- and (Z)-alkenes, respectively, although the exact mechanism is unclear The successful release of alkene from the thiophosphinic amide 175 is possible after methylation to 176 the yields of unsymmetrical disubstituted alkenes are 50 99%, and even for tri- and tetra-substituted alkenes yields of 53-93% are achievable . 

Cl2PSi3C,gH27, Phosphonous dichloride, [tris(trimethylsilyl)methyl]-, 27 239 Cl2P2PtC2gH24, Platinum, dichloro[l,2-ethanediylbis(diphenylphosphine)]-, 26 370... 

DCA sensitisation of tri-1-naphthyl phosphate or di-l-naphthyl methyl-phosphonate results in formation of l,r-binaphthyl. The reaction occurs only in compounds with at least two naphthyl substituents linked by an 0-P(0)-0 chain. Reaction involves intramolecular face-to-face dimerisation of the two naphthyl units within the radical cation (445), followed by elimination of the 1,1 -binaphthyl radical cation, which is subsequently reduced by the DCA radical anion. In a related reaction DCA-sensitisation of bis(3,4-methylenedioxy-phenyl) methylphosphonate in acetonitrile gives 2-(3,4-methylenedioxyphenyl)-4,5-methylenedioxyphenyl methylphosphonate whereas direct irradiation in methanol gives bis(3,4-methylenedioxy)biphenyl as an additional product. " ... 

To a stirred solution of 105 g (0.396 mole) of [phenyl(tri-methylsilyl)methyl]phosphonous dichloride in 2-2.5 L of diethyl ether in a 4-L flask, 178 g (1.584 moles) of l,4-diazabicyclo[2.2.2]octane (DBO) is added. The mixture is stirred overnight at ambient temperature and then filtered. The solid is washed three times with 100-mL portions of pentane. The collected filtrates are concentrated to 1.5 L at ambient temperature under reduced pressure, and the base and its hydrochloride are separated by filtration. The solid is washed three times with 50-mL portions of pentane. This procedure (concentration and... 

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