Phosphonic acid, methyl dimethyl ester

Alternative Names/Abbreviations Phosphonic acid methyl-dimethyl ester, DMMP... 

Phosphonic acid, methyl-, dimethyl ester. See Dimethyl methylphosphonate Phosphonic acid, methyl-, (5-ethyl-2-methyl-2-oxido-1,3,2-dioxaphosphorinan-5-yl) methyl methyl ester, p-oxide. See Methylphosphonic acid, (5-ethyl-2-methyl-2-oxido-1,3,2-dioxaphosphorinan-5-yl) methyl methyl ester Phosphonic acid, methyl (5-methyl-2-methyl-1,3,2-dioxaphosphorinan-5-y) ester,P,P -dioxide. See Methylphosphonic acid, bis [(5-ethyl-2-methyl-2-oxido-1,3,2-dioxaphosphorinan-5-yl) methyl] ester Phosphonic acid, [nitriliotris (methylene)] tris-, sodium salt. See Sodium nitrilotris (methylene phosphate)... 

Bellstein Handbook Reference) AI3-08678 BRN 0878263 CCRIS 876 DImethoxymethyl-phosphIne oxide Dimethyl methanephosphonate Di-methyl methylphosphonate DMMP EINECS 212-062-3 Fyrol DMMP HSDB 2590 Methyl phosphonic acid, dimethyl ester NCI-C54762 NSC 62240 Phosphonic add, methyl-, dimethyl ester Pyrol dmmp. Flame retardant for applications where high phosphorus content, good solvency, and low viscosity are desired lowers viscosity of epoxy resins and unsaturated polyesters filled with hydrated alumina oxide. Liquid bp = 181 , bp20 = 79.6" d ° = 1.4099 Am = 217 nm (e = 13, EtOH) soluble in H2O, Et20, EtOH LDsO (rat orl) > 5000 mg/kg. Akzo Chemie. 

DIETHYLPHOSPHONOMETHYL-2, 2-DIMETHYL-1.3-DI0XEN-4-0NE, 66, 194-196, 202 Diethyl phthalimidomethylphosphonate Phosphonic acid, (phthalimidomethyl)-, diethyl ester Phosphonic acid, [(1,3-dihydro-l, 3-dioxo-2H-isoindol-2-yl)-methyl]-, diethyl ester (33512-26-4), 65, 119 DIHYDR0JASM0NE, 65, 26... 

Reports on arylphosphonates include the synthesis and resolution of new racemic phosphonic acid methyl (213) and dimethyl esters (214) via cinchonium salts (Scheme 56). The absolute configuration of the phosphonic ester products was also established. 

FePC,6H27, Iron, tetracarbonyl(tri-tert-bu-tylphosphine)-, 25 155 04NPCsH,g, Phosphonic acid, [(, N-di-diethylcarbamoyl)methyl]-, dimethyl ester, 24 101... 

C 1H15NO2S 3339-36-4) see. Tiemoniuin iodide (2-oxononyl)phosphonic acid dimethyl ester (C11H23O4P 57497-25-9) see Unoprostone isopropyl (S)-4-[[4-[(2-oxo-4-oxazolidinyl)methyl]phenyl]hydrazo-no]butanenitrile... 

C3H4O3 127-17-3) see Perindopril (2-oxopropyl)phosphonic acid dimethyl ester (C5H),04P 4202-14-6) see Latanoprost 11 -oxo-3-(l-pyrrolidinyl)prcgna-3,5,17(20)-trien-21-oic acid methyl ester... 

Diethylphosphonomethyl-2,2-dimethyl-1,3-dioxen-4-one Phosphonic acid, [(2,2-dimethyl-4-oxo-4H-l, 3-dioxin-5-yl)methyl] -, diethyl ester (11) (81956-28-7)... 

CKH,40 110-93-0) see Hcptaminol lsoinelheplene (3-methyl-2-oxo-5-hcptynyl)phosphonic acid dimethyl ester... 

SYNS BIS(HYDROXYMETHYL)PHOSPHINE OXIDE DIMETHOXYPHOSPHINE OXIDE DIMETHYL ACID PHOSPHITE DIMETHYLESTER KYSEUNY FOSFORITE (CZECH) DIMETHYLFOSFIT DIMETHYLFOSFONAT DLMETHYLHYDRO-GENPHOSPHITE DLMETHYL PHOSPHITE DIMETHYL PHOSPHONATE DIMETHYL PHOSPHOROUS ACID HYDROGEN DIMETHYL PHOSPHITE METHYL PHOSPHONATE NCI-C54773 PHOSPHOROUS ACID DIMETHYL ESTER... 

METHYI- PHOSPHATE see TMD250 METHYL PHOSPHITE see TAIDSOO METHYL PHOSPHONATE see DSG600 METHYLPHOSPHONIC ACID DIMETHYL ESTER see DSR400... 

Griffin, C.E., and Mitchell, T.D., Phosphonic acids and esters. Part 10. Oxygen to carbon methyl migration in the reaction of trimethyl phosphite with dimethyl acetylenedicai boxylate, J. Org. Chem., 30. 2829, 1965. 

Methyl Phosphonic Acid, Dimethyl Ester A223 Precursor 128... 

New developments in the synthesis of a-hydroxy phosphonic acids and their derivatives have concentrated on their asymmetric formation. The chiral phosphonic diamides (629) (in which R = isopropyl, 2,2-dimethylpropyl, or benzyl or a derivative thereof) in either racemic or optically active forms were converted into their anions and allowed to react with aldehydes to give the products (630) the diastereoisomeric composition of the latter could be ascertained by the use of P NMR spectroscopy, and after acidic hydrolysis and subsequent methylation (diazomethane) it was possible to isolate optically active forms of the dimethyl esters of (l-hydroxyalkyl)phos-phonic acids, the (/ ,R)-diamide giving rise to the (5)-acids as their esters. The best results were achieved when R = Bu CFl2, and enantiomeric excesses were generally above 85% . 

Dimethyl phosphorous acid DMHP Hydrogen dimethyl phosphite Methyl phosphonate Phosphonic acid, dimethyl ester Phosphorous acid, dimethyl ester... 

It was found that the transesterification of dimethyl H-phosphonate with 1,2-propane-diol yields 4-methyl-2-hydro-2-oxo-l,3,2-dioxaphospholane [56]. Obviously, the first stage of the reaction furnished methyl-2-hydroxypropyl H-phosphonate. Subsequent intramolecular transesterification of the methyl-2-hydroxypropyl phosphonate yielded 4-methyl-2-hydro-2-oxo-l,3,2-dioxaphospholane. The specific reactivity of these esters of H-phosphonic acid is determined by the presence of a P-hydroxyl gronp. The role of the P-hydroxyl gronp may be regarded as an intramolecular catalysis. The reactivity enhancement of P-hydroxylethyl esters of H-phosphonic acid probably can be explained through hydrogen bonding, which favors the intramolecular transesterification reaction. 

In the presence of AICI3, ring opening (pathway B) occurs, resulting in the formation of a mixture of dimethyl ester of 2-hydroxyl-2-methyl-l-acetopropylphosphonic acid and l-hydroxyl-2-methyl-2-acetoisopropylphosphonic acid. NMR spectra showed signals at 23-26 ppm, which is characteristic for the phosphonate structure. 

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