Phos trichloride

Phosphor-athcr, m. phosphoric ether (ester of phosphoric acid, specif, ethyl phosphate), -basis, phosphorus base, -bestimmung, /. determination of phosphorus, -blei, n. lead phosphide Min.) pyromorphite. -bombe, f. phosphorus bomb. -brandgranate, /. phosphorus incendiary shell, -brei, m. phosphorus paste, -bromid, n. phosphorus bromide, specif, phosphorus pentabromide, phos-phorus(V) bromide, -bromijr, n. phosphorus tribromide, phosphorus(III) bromide, -bronze, /. phosphor bronze, -calcium, n. calcium phosphide, -chlorid, n. phosphorus chloride, specif, phosphorus pcntachloride, phosphorus(V) chloride, -chloriir, n. phosphorous chloride (phosphorus trichloride, phosphorus(III) chloride), -dampf, tn. phosphorus vapor or fume, -eisen, n. ferrophos-phorus iron phosphide, -eisensinter, m. diadochite. 

Interaction of the fluorides to produce chlorotetrafluorophosphorane [1] is uncontrollably violent even at — 196°C [2], An improved method of making the phos-phorane from phosphorus pentafluoride and boron trichloride is detailed [2],... 

MRH Phosphorus trichloride 3.10/67, phosphorus pentachloride 4.89/65, phos-phoryl chloride 4.27/69, sulfinyl chloride 5.27/67... 

As previously stated (p. 53) di-(2-chloroethyl) phosphoro-fluoridate can be prepared by the action of phosphorus oxydi-chlorofluoride on ethylene chlorohydrin. The compound can also be prepared by the fluorination of di (2-chloroethyl) phos-phorochloridate, prepared from di-(2-chloroethyl) hydrogen phosphite (XVIII), obtained by the action of phosphorus trichloride on ethylene chlorohydrin. This partial fluorination was effected by means of sodium fluoride, although the yield was not high. The chlorine atoms of the 2-chloroethyl groups were not affected by this procedure, a fact which falls into line with the observations of Saunders and Stacey (p. 12) that ethylene chlorohydrin is not readily fluorinated by sodium fluoride, but only by potassium fluoride under pressure in a rotating autoclave.1... 

The volatility of phosphorus trichloride, ethylphosphonous dichloride and sulphuryl chloride, permit of their quantitative transfer in a high-vacuum system. The conversion of the phos-phonous into the phosphonic dichloride can also be carried out in an enclosed system.5... 

Phosphorus trichloride reacts with chlorine in excess to give phos phorus pentachloride, an equilibrium being set up ... 

Dimethylamine, reaction with phos-I)horus trichloride 46, 42 /i-Dimethylaminobenzaldehyde, conversion to 8,8-dichloro-/i-dimethyl-aminoslyrcne, 46, 34... 

Weeks MH, Musselman NP, Yevich PP, et al Acute vapor toxicity of phosphorus oxychloride, phosphorus trichloride and methyl phos-phonic dichloride. Am Ind Hyg Assoc J 25 470-475, 1964... 

To recrystallize, the crude product is heated with 150 ml. of anhydrous methanol on a water bath. The solution is filtered hot, and after cooling, the precipitated phos-phoryl triamide is sucked off. The mother liquid is discarded as it always contains some chloride. The remaining, undissolved crude material is next treated in the same manner with another 200 ml. of anhydrous methanol. The mother liquid of this run is retained to recrystallize the rest of the crude product. The collected precipitates are dried under vacuum. Paper chromatography shows the product to be pure. The yield is 26 g. 70% calculated for phos-phoryl trichloride. 

Zyk et al. <2000RJ0794> reported the synthesis of fused-ring thietanes by the reaction of the bis-morpholine sulfide-phosphoryl trihalide complex 85 with norbornadiene. The formation of 4-thiatricyclo[3.2.1.03,6]octane 86 was demonstrated and yields varied slightly depending on the phosphoryl trihalide used. When phosphoryl trichloride was used, the yield was 69% in the case of phosphoryl tribromide, it was 72%. The complex 84 was obtained by the reaction of the bis-morpholine sulfide with phosphoryl trihalide in dichloromethane at —40°C (Scheme 15). The same authors <1996RCB2393> performed a similar reaction of norbornadiene with bis-morpholine disulfide-phos-phoryl tribromide complex 87, which led to the formation of the same thietane 86 in 63% yield (Scheme 15). These reactions have also been described by Robin and Rousseau in a review <2002EJ03099>. 

Durch Umsetzung mit Guanidm-Hydrochlorid in Chloroform bei 20—40° kann das Phos-phorsaure-(amino-imino-methylimid)-trichlorid-Hydrochlorid in hoher Ausbeute erhal-ten werden110 ... 

Open the three-way stopcock to the blubber and add dropwise the phos-phorus(lll) trichloride solution to the Grignard reagent at 0°C. 

Pre >awtions have also been achieved by reing the eorre S]>onding arsinie acids, either by pho.sphorus trichloride, r by sulphur dioxide in the presence of H)tas.sium ihydrochloric acid solution,... 

Agrofoglio has reported the syntheses of carbocyclic analogues of phos-phononucleosides (28a-e). Compound (28a) was synthesised by introducing the heterocycle under Mitsunobu conditions, while compounds (28b-e) were obtained by building up the base around a cyclopentylamine moiety0-Alkyl-ff-phosphonates of AZT (29a-e) and D4T (30a-e) have been prepared via a simple one-pot route under mild conditions and in reasonable isolated yields using phosphorus trichloride, followed by alcoholysis and dealkylation by triethylamine. ... 

Monodentate phosphites are another type of prominent monodentate phosphorus ligands applied in asymmetric hydrogenation of enamides for the synthesis of chiral amines. Chiral monodentate phosphites can be easily prepared from a chiral diol and an alcohol. Generally, the chiral diol was first reacted with a phosphorus trichloride to form a phosphorochloridite, followed by the reaction with an appropriate alcohol to yield a chiral monodentate phosphite [35[. The reaction of an alcohol with phos phorus trichoride to yield a phosphorodichloridite, which was then treated with a chiral diol, is also a good procedure for the synthesis of chiral monodentate phosphites [36]. 

Tetrakis(dimethylamino)titaiiium, Ti[N(CH3)2]4 [1, 1142, before Tetrakis-phos-phorus trichloride-nickel(O)]. Mol. wt. 225.20, orange liquid, b.p. 5070.05 mm. Prepared in 85% yield by reaction of titanium tetrachloride with lithium dimethyl-amine.1... 

Phosphorus trichloride is the starting material used most frequently for the preparation of the esters, amides and anhydrides of phosphoric and phos-phorothioic acids. It can be oxidised to phosphoryl chloride (4) and, heated with sulfur in the presence of a catalyst, to thiophosphoryl chloride (5) (Perot, 1962). 

General procedure for the preparation of diarylphosphine oxides from mesitylene, durene and pentamethylbenzene 154 The hydrocarbon (0.3 mole) is treated with phosphorus trichloride and aluminum chloride as in the preceding prescription. After addition of the phos-... 

Diphenylacetylenes. In a recent synthesis of diphenylacetylenes, the phos-phorochloridite (1) was allowed to react with a benzyl alcohol in the presence of triethylamine to form a phosphorodiamidite (2). Reaction of (2) with a benzo-trichloride gave (3), which was converted into a diphenylacetylene (4) on dehydrochlorination. Diphenylacetylene itself was obtained in 62% overall yield ... 

P-O-P-P-acid is also formed by the reaction of P-P-acid with phos-phoryl trichloride,... 

A simple but novel transformation is that of a phosphinic acid into the analogous phos-phinothioic chloride in one practical step by the action of thiophosphoryl trichloride. ... 

We prepared diethyl phosphorochloridite, PCl(OEt)2, (a) by the action of phosphorus trichloride on triethyl phosphite, 2P(OEt)2-l-PCl3 ---> 3PCl(OEt)2, or (b) by the action of phos-... 

The C3 tertiary phosphine (170) was obtained in moderate yield following a one-pot procedure involving successive quenching of lithium 2-bromophenolate with phosphorus trichloride and phos-... 

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