Benzo trichloride

The common names of (di chloromethyl)benzene and (trichloromethyl)benzene are benzal chloride and benzo trichloride respectively... 

If toluene is chlorinated to benzo-trichloride, the substitution reaction has oxidized the carbon atom of the methyl group to the acid stage and no further oxidation is necessary. At that point, hydrolysis alone is sufficient ... 

The synthesis of fluotrimazole starts from m-xylene. Peroxide catalyzed perchlorination converts this to m-trichloromethyl-benzo-trichloride. m-Trichloromethyl-benzotrifluoride is then obtained by selective chlorine/fluorine exchange. This key product is also readily accessible on a technical scale by conproportionation of the two corresponding m-trihalomethyl-benzotrihalogenides. Friedel-Crafts reaction with benzene leads to trifluoromethyl-tritylchloride, which reacts smoothly with 1,2,4-triazole in polar solvents to give fluotrimazole. 

Doebner, D. and Stackman, W. 1876. Ueber die einwirkung des benzo-trichlorids auf phenol. Chem. Ber. 9 1918-1920. 

Diphenylacetylenes. In a recent synthesis of diphenylacetylenes, the phos-phorochloridite (1) was allowed to react with a benzyl alcohol in the presence of triethylamine to form a phosphorodiamidite (2). Reaction of (2) with a benzo-trichloride gave (3), which was converted into a diphenylacetylene (4) on dehydrochlorination. Diphenylacetylene itself was obtained in 62% overall yield ... 

The earliest mention of benzoic acid appears in the sixteenth century. The substance received its name from gum bezoin, the plant from whose resin it was first derived. This plant was for a long time the only source for this acid. In the nineteenth century, benzoic acid was synthesized from coal tar. Today it is manufactured by treating molten phthalic anhydride with steam in the presence of a zinc oxide catalyst, by the hydrolysis of benzo-trichloride, or by the oxidation of toluene with nitric acid or sodium dichromate or with air in the presence of a transition metal salt catalyst. The estimated global production capacity for this acid is about 600,000 tonnes per year. 

Preparation by reaction of benzo-trichloride with 3-hydroxy-4 -methyldiphenyl ether in solution of 2.5 N sodium hydroxide in the presence of potassium iodide at 80° [839]. 

Preparation by reaction of benzenyl trichloride (benzo-trichloride) with p-dodecylphenol in carbon disulfide inthe presence of aluminium chloride, first between -20° and -15°, then at 0-5° for 1 h (38%) [889-891]. 

Benzoic acid Hydrolysis of nitrile hydrolysis of benzo-trichloride... 

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