Peritoneal dissemination

Mamede, M., Saga, T., Kobayashi, H., Ishimori, T., Higashi, T., Sato, N., Brechbiel, M.W., and Konishi, J. (2003) Radiolabeling of avidin with very high specific activity for internal radiation therapy of intra-peritoneally disseminated tumors. Clin. Cancer Res. 9, 3756-3762. 

Stewart JH, Shen P, Russell GB, Bradley RF, Hundley JC, Loggie BL, Geisinger KR, Levine EA (2006) Appendiceal neoplasms with peritoneal dissemination outcomes after cytoreductive surgery and intraperitoneal hyperthermic chemotherapy. Annals of Surgical Oncology 13 624-634. 

Kikuchi, A., Aoki, Y., Sugaya, S., et al. (1999). Development of novel cationic liposomes for efficient gene transfer into peritoneal disseminated tumor. Human. Gene Then 10 (6), 947-55. 

Hajri, A., Wack, S., Lehn, P., Vigneron, J.P. and Lehn, J.M. (2000) Efficient transfer of double suicide genes (herpes simplex virus-thymidine kinase and Escherichia coh-CD) into peritoneal disseminated pancreatic tumor cells by the cationic lipid BGTC. Cancer Gene Ther., 7,1393-1393. 

Sadzuka, Y., Hirota, S., and Sonobe,T. (2000), Intraperitoneal administration of doxorubicin encapsulating liposomes against peritoneal dissemination, Toxicol. Lett., 116, 51-... 

After intraperitoneal injection into a murine disseminated peritoneal tumor model, however, folate lipoplex formulations produced an approximately 10-fold increase in tumor-associated gene expression, compared with conventional complex [68]. When gene expression was measured in tumors and various peritoneal organs after intraperitoneal administration, the highest gene expression was observed in tumor cell ascites, followed by solid tumors. Thus, intraperitoneal administration of the folate-PEG-lipid-containing liposome complex may be more suitable for peritoneal dissemination. 

Kobayashi, H. Y. Fukuda R. Yoshida Y. Kanada S. Nishiyama M. Suzuki N. Kanayama T. Terao. Suppressing effects of dietary supplementation of soybean trypsin inhibitor on spontaneous, experimental and peritoneal disseminated metastasis in mouse model. Int. J. Cancer, 2004a, 112, 519-524. 

Minagawa A, Otani Y, Kubota T, Wada N, Furukawa T, Kumai K, Kameyama K, Okada Y, Fuji M, Yano M, Sato T, Ito A, Kitajima M. The citrus flavonoid, nobiletin, inhibits peritoneal dissemination of human gastric carcinoma in SCID mice. Jpn J Cancer Res 2001 92 1322-1328. 

Endodermal sinus tumors are foimd in women at a median age of 18 years, often diffuse peritoneal dissemination is already present at the time of diagnosis... 

Fig. 10.14a,b. Stage IV ovarian cancer. CT in the pelvis (a) and lower thorax (b).At the time of diagnosis, the patient presented with bilateral ovarian tumors encasing the uterus (a). Furthermore, left cardiophrenic lymph node enlargement and a pleural mass (arrow) were found (b). Biopsy of the latter confirmed metastases from ovarian adenocarcinoma. No evidence of ascites or peritoneal dissemination was found at imaging and surgery... 

Yonemura Y, Bandou E, Kinoshita K, Kawamura T, Taka-hashi S, Endou Y, Sasaki T. (2003) Effective therapy for peritoneal dissemination in gastric cancer. Surg Oncol Clin N Am 12 635-648... 

Peritoneal dissemination is associated with he-moperitoneum and/or intraperitoneal masses. 

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