Genes and cancer

Kato K, Long NK, Makita H, Toida M, Yamashita T, Hatakeyama D, Hara A, Mori H, Shibata T (2008) Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells. Br J Cancer 99 647-654... 

Boldogkoi, Z. and Nogradi, A., Gene and cancer therapy — pseudorabies virus a novel research and therapeutic tool Curr. Gene Ther., 3,155, 2003. 

Additional genes and protein receptors are believed to be important in colorectal tumorigenesis. Cyclooxygenase 2 (COX-2), which is induced in colorectal cancer cells, influences apoptosis and other cellular functions in colon cells, and overexpression of the epidermal growth factor receptor (EGFR), a transmembrane glycoprotein involved... 

Woodson, K, J Gillespie, J Hanson, M Emmert-Buck, JM Phillips et al. 2004. Heterogeneous gene methyla-tion patterns among pre-invasive and cancerous lesions of the prostate a histopathologic study of whole mount prostate specimens. Prostate 60(1) 25-31. 

Spitz, M.R., Shi, H., Yang, F. et al. Case-control study of the D2 dopamine receptor gene and smoking status in lung cancer patients [see comment], J. Natl. Cancer Inst. 90 358, 1998. 

UDP-glucuronosyltransferase gene and irinotecan toxicity a pharmaco-genetic analysis, Cancer Res. 2000, 60, 6921-6926. 

Rohlfs EM, Puget N, Graham ML et al. An Alu-mediated 7.1 kb deletion of BRCA1 exons 8 and 9 in breast and ovarian cancer families that results in alternative splicing of exon 10. Genes Chromosomes Cancer 2000 28[3] 300—307. 

Kool M, van der LM, de Haas M, Baas F, Borst P. Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells. Cancer Res 1999 59(1) 175 182. 

Johnston PG, Lenz HJ, Leichman CG et al. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995 55 1407-1412. 

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