Pemphigoid

D Ambra-Cabry K, Deng DH, Flynn KL, et al. Antigen retrieval in immunofluo-rescent testing of bullous pemphigoid. Am. J. Dermatopathol. 1995 17 560-563. 

SH3 domain Kakapo, plectin, and Bullous pemphigoid antigen 1 Drosophila Kakapo (917-971) PSI-BLAST (3) 7 X 10 Human ITK Tyrosine kinase SH3... 

Pemphigoid-type Pemphigoid-type reactions characterized by bullous lesions have required discontinuation of penicillamine and treatment with corticosteroids. 

Pemphigoid rash Pemphigoid rash, the most serious dermatologic reaction occurs most often after 6 to 9 months of penicillamine. 

Possibly effective Possibly effective in the following conditions Bullous pemphigoid. 

Topical corticosteroids are most useful in inflammatory dermatoses, such as eczematous dermatitis and psoriasis they may also be helpful in other skin diseases that have a prominent inflammatory component, such as autoimmune blistering diseases (e.g., bullous pemphigoid and pemphigus vulgaris) and lupus erythematosus. 

Unlabeled Uses Treatment of biliary cirrhosis, chronic acfive hepatitis, glomerulonephritis, inflammatory bowel disease, inflammatory myopathy, multiple sclerosis, myasthenia gravis, nephrotic syndrome, pemphigoid, pemphigus, polymyositis, systemic lupus erythematosus... 

Alopecia, tinnitus, pemphigoid rash (water blisters)... 

Antimetabolites Psoriasis, pemphigus, pemphigoid See also Chapter 54. 

Corticosteroids Pemphigus, pemphigoid, lupus erythematosus, allergic contact dermatoses, and certain other dermatoses See also Chapter 39. 

Dapsone Dermatitis herpetiformis, erythema elevatum diutinum, pemphigus, pemphigoid, bullous lupus erythematosus See also Chapter 47. 

Shore, J.W., Foster, C.S., WestfaU, C.T., Rubin, P.A. Results of buccal mucosal grafting for patients with medically controlled ocular cicatricial pemphigoid. Ophthalmology 99, 383-395 (1992)... 

Stoebner P. Lichen plan pemphigoide induit par la simvastatine. Ann Dermatol Venereol 2003 130 187-90. 

Brown, A., Bernier, G., Mathieu, M., Rossant, J., and Kothary, R. (1995). The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1. Nature Genet. 10, 301-306. 

Green, K. J., Virata, M. L. A., Elgart, G. W., Stanley, J. R., and Parry, D. A. D. (1992b). Comparative structural analysis of desmoplakin, bullous pemphigoid antigen and plectin Members of a new gene family involved in organization of intermediate filaments. Int. J. Biol. Macromol. 14, 145—153. 

Okumura, M., Yamakawa, H., Ohara, O., and Owaribe, K. (2002). Novel alternative splicings of BPAG1 (bullous pemphigoid antigen 1) including the domain structure closely related to MAGF (microtubule actin cross-linking factor). J. Biol. Chem. 277, 6682-6687. 

Sawamura, D., Li, K., Chu, M.-L., and Uitto, J. (1991). Human bullous pemphigoid antigen (BPAG1). Amino acid sequences deduced from cloned cDNAs predict biologically important peptide segments and protein domains. J. Biol. Chem. 266, 17784-17790. 

Stanley, J. R., Hawley-Nelson, P., Yuspa, S. H., Shevach, E. M., and Katz, S. I. (1981). Characterization of bullous pemphigoid antigen A unique basement membrane protein of stratified squamous epithelia. Cell 24, 897-903. 

Westgate, G. E., Weaver, A. C., and Couchman, J. R. (1985). Bullous pemphigoid antigen localization suggests an intracellular association with hemidesmosomes. J. Invest. Dermatol. 84, 218-224. 

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